Overexpression of monocyte chemoattractant protein 1 in systemic sclerosis: Role of platelet-derived growth factor and effects on monocyte chemotaxis and collagen synthesis

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

1980 • 4,703 citations

Scleroderma (systemic sclerosis): classification, subsets and pathogenesis

2001 • 3,883 citations

Chemokines — Chemotactic Cytokines That Mediate Inflammation

1998 • 3,660 citations

The Functional Role of the ELR Motif in CXC Chemokine-mediated Angiogenesis

1995 • 1,222 citations

Abnormalities in Monocyte Recruitment and Cytokine Expression in Monocyte Chemoattractant Protein 1–deficient Mice

1998 • 1,022 citations

PLATELET-DERIVED GROWTH FACTOR

1989 • 967 citations

Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8

1991 • 813 citations

Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis.

1992 • 667 citations

Leukocyte polarization in cell migration and immune interactions

1999 • 622 citations

Fibroblasts as sentinel cells. Synthesis of chemokines and regulation of inflammation.

1997 • 499 citations

RANTES and Monocyte Chemoattractant Protein–1 (MCP-1) Play an Important Role in the Inflammatory Phase of Crescentic Nephritis, but Only MCP-1 Is Involved in Crescent Formation and Interstitial Fibrosis

1997 • 498 citations

Costimulation of Fibroblast Collagen and Transforming Growth Factor β1 Gene Expression by Monocyte Chemoattractant Protein-1 via Specific Receptors

1996 • 427 citations

Differential CC chemokine-induced enhancement of T helper cell cytokine production.

1997 • 417 citations

Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes

1991 • 369 citations

Lymphocytes in the skin of patients with progressive systemic sclerosis

1984 • 369 citations

Cytokine induction of monocyte chemoattractant protein‐1 gene expression in human endothelial cells depends on the cooperative action of NF‐χB and AP‐1

1997 • 318 citations

Stimulation of Collagen and Glycosaminoglycan Production in Cultured Human Adult Dermal Fibroblasts by Recombinant Human Interleukin 6

1991 • 315 citations

MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphoctye differentiation

1997 • 312 citations

Type 2 helper T-cell predominance and high CD30 expression in systemic sclerosis.

1997 • 210 citations

Increased expression of the monocyte chemoattractant protein-1 in bronchial tissue from asthmatic subjects.

1994 • 201 citations

Platelet‐derived Growth Factor

1995 • 200 citations

Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1α (MIP-1α) and MIP-1β) in patients with systemic sclerosis: MCP-1 and MIP-1α may be involved in the development of pulmonary fibrosis

1999 • 197 citations

Activation of nuclear factor-κB correlates with MCP-1 expression by human mesangial cells

1995 • 185 citations

Selective upregulation of platelet-derived growth factor alpha receptors by transforming growth factor beta in scleroderma fibroblasts.

1992 • 181 citations

PATHOGENESIS OF SCLERODERMA

1996 • 178 citations

Endogenous IL-1α from systemic sclerosis fibroblasts induces IL-6 and PDGF-A

1999 • 178 citations

Identification of Fibroblasts Responsible for Increased Collagen Production in Localized Scleroderma by In Situ Hybridization

1988 • 176 citations

Immunohistologic Demonstration of Platelet-derived Growth Factor (PDGF) and sis-Oncogene Expression in Scleroderma

1989 • 173 citations

Lung monocyte chemoattractant protein-1 gene expression in bleomycin-induced pulmonary fibrosis.

1994 • 164 citations

Elevated levels of platelet derived growth factor and transforming growth factor-beta 1 in bronchoalveolar lavage fluid from patients with scleroderma.

1995 • 153 citations

IMMUNOPATHOGENESIS OF SYSTEMIC SCLEROSIS

1996 • 150 citations

Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE.

1990 • 145 citations

Novel roles for chemokines and fibroblasts in interstitial fibrosis

1998 • 130 citations

Normal Human Primary Fibroblasts Undergo Apoptosis in Three-Dimensional Contractile Collagen Gels

1998 • 130 citations

Modulation of JE/MCP-1 expression in dermal wound repair.

1995 • 130 citations

Endothelial and fibroblastic activation in scleroderma: The myth of the “uninvolved skin”

1991 • 123 citations

Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen‐producing cells in systemic sclerosis fibroblasts

1996 • 116 citations

Induction of monocyte chemotactic proteins MCP-1 and MCP-2 in human fibroblasts and leukocytes by cytokines and cytokine inducers. Chemical synthesis of MCP-2 and development of a specific RIA.

1994 • 114 citations

Novel CXCR2‐dependent liver regenerative qualities of ELR‐containing CXC chemokines

1999 • 107 citations

Association of microsatellite markers near the fibrillin 1 gene on human chromosome 15q with scleroderma in a Native American population

1998 • 103 citations

Growth Regulation in Scleroderma Fibroblasts: Increased Response to Transforming Growth Factor-β1

1995 • 99 citations

Platelet-derived Growth Factor Induction of the Immediate-early gene Is Mediated by NF-κB and a 90-kDa Phosphoprotein Coactivator

1996 • 88 citations

Through the looking glass: the diverse in vivo activities of chemokines

1999 • 87 citations

Expression of vascular cell adhesion molecule-1 mRNA and protein in rheumatoid synovium demonstrated by in situ hybridization and immunohistochemistry.

1995 • 85 citations

Studies of the microvascular endothelium in uninvolved skin of patients with systemic sclerosis: direct evidence for a generalized microangiopathy

2008 • 83 citations

Fibroblasts, Mononuclear Phagocytes, and Endothelial Cells Express Monocyte Chemoattractant Protein‐1 (MCP‐1) in Inflamed Human Gingiva

1995 • 81 citations

Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: Different sensitivity to inhibition between systemic sclerosis and control fibroblasts

1998 • 68 citations

Scleroderma fibroblasts promote migration of mononuclear leucocytes across endothelial cell monolayers

1998 • 63 citations

Biology of the scleroderma fibroblast

1998 • 58 citations

Identification of elements in the promoter region of the ?1(I) procollagen gene involved in its up-regulated expression in systemic sclerosis

1998 • 58 citations

Expression and regulation of human pulmonary fibroblast-derived monocyte chemotactic peptide-1

1992 • 57 citations

Transcriptional activation of the α1(1) procollagen gene in systemic sclerosis dermal fibroblasts. Role of intronic sequences

1996 • 54 citations

Independent effects of platelet-derived growth factor isoforms on mitogen-activated protein kinase activation and mitogenesis in human dermal fibroblasts

1994 • 48 citations

Expression of monocyte chemoattractant protein-1 in delayed type hypersensitivity reactions in the skin.

1994 • 48 citations

Expression of RANTES in biopsies of skin and upper gastrointestinal tract from patients with systemic sclerosis

1999 • 41 citations

Enhanced interleukin 6 production by cultured fibroblasts from patients with systemic sclerosis in response to platelet derived growth factor.

1998 • 38 citations

Scleroderma Fibroblasts Show Increased Responsiveness to Endothelial Cell–Derived IL-1 and bFGF

1997 • 35 citations

Human lung fibroblasts release chemokinetic activity for monocytes constitutively

1998 • 32 citations

Structure of the Mutant Fibrillin-1 Gene in the Tight Skin (TSK) Mouse

1997 • 25 citations

Immunologic aspects of scleroderma

1995 • 20 citations

Immunologic aspects of scleroderma

1994 • 20 citations

Deleted Work

1955 • 0 citations