Recombinant human MCP-1/JE induces chemotaxis, calcium flux, and the respiratory burst in human monocytes

Neutrophil-activating peptide-1/interleukin 8, a novel cytokine that activates neutrophils.

1989 • 1,993 citations

Molecular cloning of gene sequences regulated by platelet-derived growth factor

1983 • 989 citations

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

1987 • 983 citations

A 48-well micro chemotaxis assembly for rapid and accurate measurement of leukocyte migration

1980 • 915 citations

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line.

1989 • 753 citations

Human monocyte chemoattractant protein-1 (MCP-1)

1990 • 666 citations

A novel neutrophil-activating factor produced by human mononuclear phagocytes.

1988 • 655 citations

Human monocyte chemoattractant protein‐1 (MCP‐1) Full‐length cDNA cloning, expression in mitogen‐stimulated blood mononuclear leukocytes, and sequence similarity to mouse competence gene JE

1989 • 593 citations

Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

1987 • 542 citations

Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE.

1990 • 500 citations

Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants.

1989 • 497 citations

Ion channels in human neutrophils activated by a rise in free cytosolic calcium concentration

1986 • 489 citations

Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.

1988 • 444 citations

Macrophage inflammatory proteins 1 and 2: members of a novel superfamily of cytokines

1989 • 435 citations

Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin.

1988 • 357 citations

Monocyte chemotactic and activating factor gene expression induced in endothelial cells by IL-1 and tumor necrosis factor.

1990 • 348 citations

Neutrophil-activating properties of the melanoma growth-stimulatory activity.

1990 • 277 citations

Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF)

1989 • 266 citations

Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture

1988 • 263 citations

The Platelet-derived Growth Factor-inducible KC Gene Encodes a Secretory Protein Related to Platelet α-Granule Proteins

1989 • 257 citations

Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line.

1990 • 241 citations

Suppression of tumor formation in vivo by expression of the JE gene in malignant cells.

1991 • 225 citations

Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophils.

1989 • 224 citations

Identification of Monocyte Chemotactic Activity Produced by Malignant Cells

1989 • 213 citations

Chemiluminescence detection of H2O2 produced by human neutrophils during the respiratory burst

1987 • 148 citations

Two inflammatory mediator cytokine genes are closely linked and variably amplified on chromosome 17q

1990 • 119 citations

The onset of the respiratory burst in human neutrophils. Real-time studies of H2O2 formation reveal a rapid agonist-induced transduction process.

1987 • 117 citations

Post-translational modification of a monocyte-specific chemoattractant synthesized by glioma, osteosarcoma, and vascular smooth muscle cells.

1990 • 93 citations

Platelet-derived Growth Factor-inducible Gene JE Is a Member of a Family of Small Inducible Genes Related to Platelet Factor 4

1989 • 90 citations

Clustering of cytokine genes on mouse chromosome 11.

1990 • 66 citations

Assignment of the human small inducible cytokine A2 gene, SCYA2 (encoding JE or MCP-1), to 17q11.2–12: Evolutionary relatedness of cytokines clustered at the same locus

1991 • 35 citations

Activation of monocytes by interferon-gamma has no effect on the level or affinity of the nicotinamide adenine dinucleotide-phosphate oxidase and on agonist-dependent superoxide formation.

1988 • 20 citations