Heterogeneity of collagen synthesis in normal and systemic sclerosis skin fibroblasts. Increased proportion of high collagen‐producing cells in systemic sclerosis fibroblasts

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Preliminary criteria for the classification of systemic sclerosis (scleroderma)

1980 • 4,703 citations

Increased Collagen Synthesis by Scleroderma Skin Fibroblasts In Vitro A POSSIBLE DEFECT IN THE REGULATION OR ACTIVATION OF THE SCLERODERMA FIBROBLAST

1974 • 545 citations

Cloning and characterization of five overlapping cDNAs specific for the human proα 1(I) collagen chain

1982 • 496 citations

Cellular infiltrates in scleroderma skin

1977 • 356 citations

Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia.

1974 • 304 citations

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.

1980 • 282 citations

Co-localization of transforming growth factor beta 2 with alpha 1(I) procollagen mRNA in tissue sections of patients with systemic sclerosis.

1990 • 219 citations

Localization of collagen mRNA in normal and scleroderma skin by in‐situ hybridization

1988 • 207 citations

Variability in Collagen and Fibronectin Synthesis by Scleroderma Fibroblasts in Primary Culture

1981 • 201 citations

Identification of Fibroblasts Responsible for Increased Collagen Production in Localized Scleroderma by In Situ Hybridization

1988 • 176 citations

Co-ordinate increase in the expression of type I and type III collagen genes in progressive systemic sclerosis fibroblasts

1986 • 173 citations

Fibroblast selection in scleroderma

1982 • 168 citations

Evaluation of Transforming Growth Factor β and Type I Procollagen Gene Expression in Fibrotic Skin Disease by In Situ Hybridization

1990 • 155 citations

Increased collagen accumulation in dermal fibroblast cultures from patients with progressive systemic sclerosis (scleroderma).

1978 • 154 citations

[24] Detection of messenger RNA by in Situ hybridization

1993 • 135 citations

Endothelial and fibroblastic activation in scleroderma: The myth of the “uninvolved skin”

1991 • 123 citations

Fibroblast prostaglandin E2 synthesis. Persistence of an abnormal phenotype after short-term exposure to mononuclear cell products.

1983 • 106 citations

Ultrastructure of Cutaneous Cellular Infiltrates in Scleroderma

1977 • 93 citations

Clonal heterogeneity in the fibroblast response to mononuclear cell derived mediators

1984 • 76 citations

Connective tissue synthesis by cultured scleroderma fibroblasts. I. In vitro collagen synthesis by normal and scleroderma dermal fibroblasts

1976 • 75 citations

Heterogeneity in hormone responses and patterns of collagen synthesis in cloned dermal fibroblasts.

1990 • 73 citations

Pulmonary Fibroblast Heterogeneity

1992 • 51 citations

Increased Procollagen mRNA Levels in Scleroderma Skin Fibroblasts

1983 • 49 citations

Steady-State mRNA Levels of Collagens I, III, Fibronectin, and Collagenase in Skin Biopsies of Systemic Sclerosis Patients

1991 • 40 citations

Scleroderma fibroblasts: Some aspects of in vitro assessment of collagen synthesis

1981 • 35 citations

Synthesis of PGE2, Collagenase and Tissue Factor by Fibroblast Substrains: Substrains are Differentially Activated for Different Metabolic Products

1985 • 34 citations

Heterogeneous synthetic phenotype of cloned scleroderma fibroblasts may be due to aberrant regulation in the synthesis of connective tissues

1988 • 33 citations

Increased collagen synthesis in skin fibroblasts from patients with primary hypertrophic osteoarthropathy. evidence for trans–activational regulation of collagen transcription

1994 • 21 citations