Collapse and Restoration of MHC Class-I-Dependent Immune Privilege

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Controls of Hair Follicle Cycling

2001 • 1,429 citations

The Biology of Hair Follicles

1999 • 1,312 citations

Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis

2000 • 1,063 citations

MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING

1998 • 1,017 citations

Mechanisms of TGF-β signaling in regulation of cell growth and differentiation

2002 • 521 citations

Human hair growth in vitro

1990 • 385 citations

Mechanisms of interleukin‐10‐mediated immune suppression

2001 • 368 citations

Analysis of apoptosis during hair follicle regression (catagen)

1997 • 353 citations

Anti-inflammatory actions of the neuroimmunomodulator α-MSH

1997 • 352 citations

The human hair follicle immune system: cellular composition and immune privilege

2000 • 341 citations

Control of murine hair follicle regression (catagen) by TGF‐β1in vivo

2000 • 334 citations

Effect of Alpha- and Beta-Melanocyte Stimulating Hormones on the Skin Colour of Man

1961 • 328 citations

HLA-G expression in early embryos is a fundamental prerequisite for the obtainment of pregnancy

2002 • 300 citations

Immunology at the Maternal-Fetal Interface: Lessons for T Cell Tolerance and Suppression

2000 • 291 citations

Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNA degradation.

1994 • 288 citations

Effects of Insulin and Insulin-Like Growth Factors on Cultured Human Hair Follicles: IGF-I at Physiologic Concentrations Is an Important Regulator of Hair Follicle Growth In Vitro

1994 • 287 citations

Interferon-κ, a Novel Type I Interferon Expressed in Human Keratinocytes

2001 • 268 citations

The Hair Follicle and Immune Privilege

2003 • 244 citations

Interleukin-10 is a growth factor for human melanoma cells and down-regulates HLA class-I, HLA class-II and ICAM-1 molecules

1997 • 239 citations

Hair follicle predetermination

2001 • 226 citations

How the immune system protects the host from infection

2001 • 225 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

The Immunology of Pregnancy

1999 • 210 citations

Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?

1993 • 197 citations

The Transporter Associated With Antigen Processing: Function and Implications in Human Diseases

2002 • 196 citations

The Role of IGF-I in Human Skin and its Appendages: Morphogen as Well as Mitogen?

1997 • 181 citations

Expression of class I and class II major histocompatibility complex antigens on human hepatocytes

1988 • 180 citations

Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506)

2001 • 144 citations

Generation and Cyclic Remodeling of the Hair Follicle Immune System in Mice

1998 • 141 citations

Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic mice

1994 • 138 citations

On the potential role of proopiomelanocortin in skin physiology and pathology

1993 • 135 citations

Class I and class II major histocompatibility complex antigen expression on hepatocytes: A study in children with liver disease

1990 • 132 citations

Immune Privilege in Hair Growth

1991 • 131 citations

The Insulin-like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia

1996 • 129 citations

Human hair growth in vitro: a model for the study of hair follicle biology

1994 • 128 citations

In situexpression of corticotropin‐releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skin

2001 • 114 citations

Immunology of the Hair Follicle: A Short Journey into terra incognita

1999 • 113 citations

Tapasin—the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum

2002 • 113 citations

Cutaneous Immunomodulation and Coordination of Skin Stress Responses by α‐Melanocyte‐Stimulating Hormone^a

1998 • 110 citations

Immunology and immunopathology of the male genital tract: Control and impairment of immune privilege in the testis and in semen

2001 • 106 citations

Mediation of Alopecia Areata by Cooperation Between CD4+ and CD8+ T Lymphocytes

2002 • 105 citations

Aqueous humor induces transforming growth factor-ß (TGF-ß)-producing regulatory T-cells

1997 • 102 citations

Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus

2002 • 98 citations

Distribution and changing density of gamma-delta T cells in murine skin during the induced hair cycle

1994 • 90 citations

Accessory proteins and the assembly of human class I MHC molecules: a molecular and structural perspective

2003 • 89 citations

Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor

1999 • 86 citations

Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata

1996 • 85 citations

Expression of classical and non-classical MHC class I antigens in murine hair follicles

2006 • 84 citations

The Transporter Associated With Antigen Processing (TAP): Structural Integrity, Expression, Function, and Its Clinical Relevance

2001 • 82 citations

Why isn't the fetus rejected?

2001 • 81 citations

Immunologically Privileged Sites in Transplantation Immunology and Oncology

1985 • 80 citations

Topical FK506: a potent immunotherapy for alopecia areata? Studies using the Dundee experimental bald rat model

1997 • 80 citations

Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles

1989 • 80 citations

IMMUNOLOGY AND IMMUNOMODULATION OF CORNEAL TRANSPLANTATION

2002 • 77 citations

Ocular Immune Privilege and the Impact of Intraocular Inflammation

2002 • 75 citations

HLA-G truncated isoforms can substitute for HLA-G1 in fetal survival

2000 • 74 citations

A Biologist'S Reflections on Dermatology

1971 • 71 citations

The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle

1999 • 70 citations

The Role of Interleukin 10 in the Regulation of Allergic Immune Responses

2001 • 69 citations

Distribution of major histocompatibility antigens in normal skin

1983 • 69 citations

Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patients

1999 • 61 citations

MHC Class I Expression in Murine Skin: Developmentally Controlled and Strikingly Restricted Intraepithelial Expression During Hair Follicle Morphogenesis and Cycling, and Response to Cytokine Treatment In Vivo

1998 • 60 citations

α-MSH regulates interleukin-10 expression by human keratinocytes

1998 • 55 citations

Cell Degeneration in Alopecia Areata

1991 • 55 citations

Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN‐γ‐inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4⁺ T‐cell activation

2001 • 49 citations

Hormonal regulation of major histocompatibility complex class I genes in rat thyroid FRTL-5 cells: thyroid-stimulating hormone induces a cAMP-mediated decrease in class I expression.

1992 • 47 citations

??-Melanocyte-stimulating hormone protects the allograft in experimental heart transplantation1

2002 • 45 citations

Hair cycle-dependent changes in the gene expression and protein content of transforming factor β1 and β3 in murine skin

1997 • 43 citations

Interferon-?-induced ICAM-1 and CD40 expression, complete lack of HLA-DR and CD80 (B7.1), and inconsistent HLA-ABC expression in basal cell carcinoma: a possible role for interleukin-10?

1999 • 40 citations

Comparative study of the role of professional versus semiprofessional or nonprofessional antigen presenting cells in the rejection of vascularized organ allografts

1995 • 39 citations

Interferon regulatory factor-1 is required for interferon-γ-induced MHC class I genes in astrocytes

2002 • 37 citations

Insulin-Like Growth Factor-I and Epidermal Growth Factor Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3) in the Human Keratinocyte Cell Line HaCaT

1995 • 33 citations

Transforming Growth Factor-β1 Down-Regulation of Major Histocompatibility Complex Class I in Thyrocytes: Coordinate Regulation Of Two Separate Elements by Thyroid-Specific as Well as Ubiquitous Transcription Factors

2000 • 29 citations

Peptide‐receptive class I major histocompatibility complex molecules on TAP‐deficient and wild‐type cells and their roles in the processing of exogenous antigens

1999 • 27 citations

Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes

1995 • 25 citations

Differential regulation of the expression of transporters associated with antigen processing, TAP1 and TAP2, by cytokines and lipopolysaccharide in primary human macrophages

2002 • 25 citations

Current Immunosuppression in Liver Transplantation

2002 • 24 citations

The effects of cyclosporin A and FK506 on proliferation and IL-8 production of cultured human keratinocytes

1995 • 22 citations

Interferon Regulatory Factor Element and Interferon Regulatory Factor 1 in the Induction of Major Histocompatibility Complex Class I Genes in Neural Cells

1995 • 19 citations

9 enhanced tyramide signal amplification immunohistochemical detection

1999 • 18 citations

Decreased Intraindividual HLA Class I Expression is due to Reduced Transcription in Advanced Melanoma and Does Not Correlate with HLA-G Expression

2001 • 14 citations

Major histocompatibility complex class II^– fetal skin dendritic cells are potent accessory cells of polyclonal T‐cell responses

2000 • 14 citations

Modulation of the Peripheral and Central Inflammatory Responses by a-Melanocyte Stimulating Hormone

2002 • 12 citations

In situ expression of corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skin

2003 • 12 citations

The Effect of α-MSH on Plasma Growth Hormone, Cortisol and TSH in Children

1975 • 12 citations

5 analysis of secretory protein trafficking within living cells

1999 • 11 citations

Role for Id‐1 in immunobiology of normal keratinocytes and in basal cell carcinoma

2003 • 8 citations