Differential regulation of the expression of transporters associated with antigen processing, TAP1 and TAP2, by cytokines and lipopolysaccharide in primary human macrophages

Secretory products of macrophages.

1987 • 2,670 citations

Interferon alfa-2b adjuvant therapy of high-risk resected cutaneous melanoma: the Eastern Cooperative Oncology Group Trial EST 1684.

1996 • 2,073 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Functional classification of interferon-stimulated genes identified using microarrays

2001 • 882 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX

1996 • 613 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

A new foreign policy: MHC class I molecules monitor the outside world

1996 • 422 citations

A role for the ubiquitin-dependent proteolytic pathway in MHC class l-restricted antigen presentation

1993 • 317 citations

Molecular Transductional Mechanisms by which IFNγ and Other Signals Regulate Macrophage Development

1987 • 266 citations

A monoclonal antibody to a differentiation antigen present on mature human macrophages and absent from monocytes.

1985 • 238 citations

Combined intraarterial 5‐fluorouracil and subcutaneous interferon‐α therapy for advanced hepatocellular carcinoma with tumor thrombi in the major portal branches

2002 • 202 citations

Polymorphism in a second ABC transporter gene located within the class II region of the human major histocompatibility complex.

1992 • 190 citations

TAP deficiency syndrome

2000 • 189 citations

Cytokines increase transporter in antigen processing-1 expression more rapidly than HLA class I expression in endothelial cells.

1992 • 115 citations

Kinetically coordinated induction of TAP1 and HLA class I by IFN-gamma: the rapid induction of TAP1 by IFN-gamma is mediated by Stat1 alpha.

1996 • 104 citations

Molecular interactions in macrophage activation

1989 • 102 citations

The role of interferon alfa in the treatment of metastatic melanoma.

1997 • 59 citations

A phase II study of neoadjuvant biochemotherapy for stage III melanoma

2002 • 52 citations

Synergistic Induction of the Tap-1 Gene by IFN-γ and Lipopolysaccharide in Macrophages Is Regulated by STAT1

2000 • 48 citations

Combination of chemotherapy with interleukin-2 and interferon-alfa for the treatment of advanced melanoma.

1994 • 46 citations

Gene Expression Studies Using Microarrays

2001 • 39 citations

Randomized trial of ?-interferon or dexamethasone as maintenance treatment for multiple myeloma

2000 • 39 citations

Adjuvant therapy for cutaneous malignant melanoma

1997 • 35 citations

Adjuvant interferon-alpha for melanoma revisited: News from old and new studies

2001 • 25 citations

Interleukin 1 and Interferon-γ: Cytokines that Provide Reciprocal Regulation of Macrophage and T Cell Function

1987 • 24 citations

Altered Kinetics of Tap-1 Gene Expression in Macrophages Following Stimulation with both IFN-γ and LPS

1997 • 14 citations

A Phase II Trial of Interferon-Alpha and Toremifene in Advanced Renal Cell Cancer Patients

2002 • 5 citations