IMMUNOLOGY AND IMMUNOMODULATION OF CORNEAL TRANSPLANTATION

Dendritic cells and the control of immunity

1998 • 14,345 citations

The expanding universe of T-cell subsets: Th1, Th2 and more

1996 • 3,710 citations

Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways

1994 • 1,073 citations

CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival.

1997 • 375 citations

CELLS MEDIATING ALLOGRAFT REJECTION

1991 • 330 citations

Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance.

1994 • 317 citations

ORTHOTOPIC CORNEAL TRANSPLANTATION IN MICE—EVIDENCE THAT THE IMMUNOGENETIC RULES OF REJECTION DO NOT APPLY

1992 • 298 citations

Eine erfolgreiche totale Keratoplastik

1906 • 280 citations

The role of FasL-induced apoptosis in immune privilege

1997 • 262 citations

Contribution of direct and indirect recognition pathways to T cell alloreactivity.

1993 • 242 citations

THE ROLE OF AFFERENT LYMPHATICS IN THE REJECTION OF SKIN HOMOGRAFTS

1968 • 224 citations

The Influence of Donor-Recipient Sensitization on Corneal Grafts*

1951 • 223 citations

Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments

1993 • 216 citations

Dendritic cells and the control of immunity: enhancing the efficiency of antigen presentation.

2001 • 215 citations

THE IMMUNE PRIVILEGE OF CORNEAL ALLOGRAFTS1

1999 • 175 citations

The Fas-Fas ligand system and other modulators of apoptosis in the cornea.

1996 • 174 citations

The distribution of HLA antigens on human corneal tissue.

1984 • 157 citations

Impaired cell-mediated immunity in mice bearing healthy orthotopic corneal allografts.

1993 • 155 citations

Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody.

1991 • 151 citations

The critical role of lymph nodes in corneal alloimmunization and graft rejection.

2001 • 150 citations

ROLE OF FAS-FAS LIGAND INTERACTIONS IN THE IMMUNOREJECTION OF ALLOGENEIC MOUSE CORNEAL TRANSPLANTS1

1997 • 147 citations

Antigen processing and presentation in transplantation

1996 • 140 citations

PROLONGATION OF SHEEP CORNEAL ALLOGRAFT SURVIVAL BY EX VIVO TRANSFER OF THE GENE ENCODING INTERLEUKIN-101

2001 • 136 citations

A T Helper Cell 2 (Th2) Immune Response against Non-self Antigens Modifies the Cytokine Profile of Autoimmune T Cells and Protects against Experimental Allergic Encephalomyelitis

1997 • 136 citations

TOPICAL INTERLEUKIN 1 RECEPTOR ANTAGONIST PROMOTES CORNEAL TRANSPLANT SURVIVAL1

1997 • 132 citations

Penetrating corneal transplantation in the inbred rat: a new model.

1985 • 127 citations

A role for eosinophils in transplant rejection

2001 • 120 citations

Role of CD4+ and CD8+ T Cells in Allorecognition: Lessons from Corneal Transplantation

2001 • 115 citations

Anterior chamber-associated immune deviation promotes corneal allograft survival.

1996 • 115 citations

Role of CD4+ T cells in immunobiology of orthotopic corneal transplants in mice.

1999 • 114 citations

Phagocytosis of particulate antigens by corneal epithelial cells stimulates interleukin-1 secretion and migration of Langerhans cells into the central cornea.

1989 • 113 citations

A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage ‘suicide’ technique

1990 • 94 citations

Expression of two molecular forms of the complement decay-accelerating factor in the eye and lacrimal gland.

1990 • 91 citations

Prolongation of rat corneal graft survival by treatment with anti-CD4 monoclonal antibody.

1992 • 90 citations

DOWN-REGULATION OF THE IMMUNE RESPONSE TO HISTOCOMPATIBILITY ANTIGENS AND PREVENTION OF SENSITIZATION BY SKIN ALLOGRAFTS BY ORALLY ADMINISTERED ALLOANTIGEN1

1992 • 89 citations

Complement regulatory activity of normal human intraocular fluid is mediated by MCP, DAF, and CD59.

2000 • 80 citations

CHARACTERISTICS OF REJECTION OF ORTHOTOPIC CORNEAL ALLOGRAFTS IN THE RAT

1988 • 76 citations

Oral Exposure to Alloantigen Generates Intragraft CD8+ Regulatory Cells

2001 • 74 citations

BALANCING THE IMMUNE SYSTEM FOR TOLERANCE

1997 • 71 citations

Perforin-dependent cytotoxic activity and lymphokine secretion by CD4+ T cells are regulated by CD8+ T cells.

1997 • 71 citations

Infiltrating inflammatory cell phenotypes and apoptosis in rejected human corneal allografts

1997 • 71 citations

The role of cytotoxic T lymphocytes in corneal allograft rejection.

2000 • 70 citations

Prevention of corneal allograft rejection in rats treated with subconjunctival injections of liposomes containing dichloromethylene diphosphonate.

1994 • 68 citations

Antigen presentation by Langerhans cells in vivo: donor-derived Ia+ Langerhans cells are required for induction of delayed-type hypersensitivity but not for cytotoxic T lymphocyte responses to alloantigens.

1986 • 67 citations

Depletion of Donor-Derived Langerhans Cells Promotes Corneal Allograft Survival

1996 • 61 citations

Effect of Donor Epithelium on Corneal Transplant Survival

1988 • 61 citations

Quantitative determinations of complement components and immunoglobulins in tears and aqueous humor.

1974 • 59 citations

A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation.

1998 • 59 citations

THE EFFECT OF ORAL IMMUNIZATION ON CORNEAL ALLOGRAFT SURVIVAL1

1996 • 59 citations

Induction of corneal graft rejection by passive cell transfer.

1976 • 56 citations

Effect of topically applied anti-CD4 monoclonal antibodies on orthotopic corneal allografts in a rat model.

1995 • 56 citations

Sex Chromatin as a Biologic Cell Marker*

1960 • 56 citations

Role of donor-specific cytotoxic T cells in rejection of corneal allografts in normal and high-risk eyes

1996 • 51 citations

Composition of cellular infiltrates in rejected human corneal allografts

1985 • 51 citations

Intracameral injection of allogeneic lymphocytes enhances corneal graft survival.

1990 • 46 citations

Mice with Th2-biased immune systems accept orthotopic corneal allografts placed in "high risk" eyes.

1999 • 46 citations

THE ASSOCIATION OF LYMPHOCYTOTOXIC ANTIBODIES WITH CORNEAL ALLOGRAFT REJECTION IN HIGH RISK PATIENTS

1995 • 41 citations

Heterotopic corneal grafting in mice: a new approach to the study of corneal alloimmunity.

1982 • 41 citations

Effect of LFA-1 and ICAM-1 antibody treatment on murine corneal allograft survival.

1994 • 39 citations

An inquiry into the possibility of transplanting the cornea, with the view of relieving blindness (hitherto deemed incurable) caused by several diseases of that structure

1837 • 39 citations

Mice with Th2-Biased Immune Systems Accept Orthotopic Corneal Allografts Placed in “High Risk” Eyes

1999 • 37 citations

THE DIFFERENTIAL EFFECTS OF DONOR VERSUS HOST LANGERHANS CELLS IN THE REJECTION OF MHC-MATCHED CORNEAL ALLOGRAFTS

1991 • 37 citations

Oral immunisation as a strategy for enhancing corneal allograft survival

1997 • 37 citations

T-cell subsets, bm mutants, and the mechanisms of allogeneic skin graft rejection

1989 • 36 citations

Lymphatic Drainage from Vascularized Rabbit Cornea

1971 • 34 citations

Anterior Chamber-Associated Immune Deviation

1999 • 33 citations

EVIDENCE THAT THE FATE OF CLASS II-DISPARATE CORNEAL GRAFTS IS DETERMINED BY THE TIMING OF CLASS II EXPRESSION

1991 • 32 citations

Histopathology of rejected orthotopic corneal grafts in the rat.

1989 • 31 citations

INDUCTION OF DONOR-SPECIFIC HYPORESPONSIVENESS AND PROLONGATION OF CARDIAC ALLOGRAFT SURVIVAL BY JEJUNAL ADMINISTRATION OF DONOR SPLENOCYTES

1999 • 29 citations

Protection of Corneal Allografts by CTLA4-Ig

1999 • 29 citations

The Immunology of Corneal Transplantation

1999 • 29 citations

Corneal transplantation in antibody-deficient hosts.

1999 • 29 citations

Inhibition of corneal allograft reaction by CTLA4-Ig

1997 • 27 citations

CORNEAL GRAFT REJECTION PROBABLY MEDIATED BY ANTIBODIES

1981 • 26 citations

Conditions affecting enhanced corneal allograft survival by oral immunization.

1998 • 24 citations

Correlation of anterior chamber-associated immune deviation with suppression of corneal epithelial rejection in mice.

1997 • 22 citations

SUPPRESSION OF ALLOGRAFT REJECTION WITH ANTI-???? T CELL RECEPTOR ANTIBODY IN RAT CORNEAL TRANSPLANTATION1

1999 • 22 citations

Effect of topical interleukin-1 receptor antagonist (IL-1ra) on corneal allograft survival in presensitized hosts

1999 • 20 citations

THE RELATIVE IMMUNOGENICITY OF CORNEAL EPITHELIUM, STROMA, AND ENDOTHLIUM

1986 • 20 citations

T cell subsets in the immune rejection of murine heterotopic corneal allografts.

1986 • 19 citations

Ability of intracamerally inoculated B- and T-cell enriched allogeneic lymphocytes to enhance corneal allograft survival

1993 • 18 citations

REGULATION OF DELAYED-TYPE HYPERSENSITIVITY

1982 • 18 citations

Circulating cornea-specific antibodies in corneal disease and cornea transplantation

1994 • 18 citations

Class I disparate corneal grafts enjoy afferent but not efferent blockade of the immune response

1991 • 17 citations

PROLONGATION OF SURVIVAL OF PRIMARY RENAL ALLOGRAFTS BY FEEDING OF DONOR SPLEEN CELLS1

1998 • 13 citations

Function and cell surface phenotype of dendritic cells from rat cornea.

1995 • 11 citations

Clinical and Immunological Results of Corneal Allograft Rejection

1986 • 10 citations

Suppressor T Cells in Mice Made Unresponsive to Skin Allografts

1988 • 9 citations

PROLONGED SURVIVAL OF CORNEAL ALLOGRAFTS INCUBATED IN ALLOANTIBODY FRAGMENTS1

1999 • 5 citations