Histamine in the immune regulation of allergic inflammation

International Union of Pharmacology: Approaches to the Nomenclature of Voltage-Gated Ion Channels

2003 • 7,170 citations

Role of interleukin 10 in specific immunotherapy.

1998 • 980 citations

IL‐10 and TGF‐β cooperate in the regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy

2003 • 911 citations

International Union of Pharmacology. XIII. Classification of histamine receptors.

1997 • 869 citations

The physiological action of β‐iminazolylethylamine

1910 • 867 citations

Cloning and Functional Expression of the Human Histamine H₃Receptor

1999 • 710 citations

Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors

2001 • 578 citations

H₁‐antihistamines: inverse agonism, anti‐inflammatory actions and cardiac effects

2002 • 435 citations

IL-18, although antiallergic when administered with IL-12, stimulates IL-4 and histamine release by basophils

1999 • 435 citations

Mice lacking histidine decarboxylase exhibit abnormal mast cells

2001 • 393 citations

Histamine Potently Suppresses Human IL-12 and Stimulates IL-10 Production via H2 Receptors

1998 • 372 citations

Molecular Cloning and Characterization of a New Human Histamine Receptor, HH4R

2000 • 356 citations

Cloning, Expression, and Pharmacological Characterization of a Novel Human Histamine Receptor

2001 • 321 citations

Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization

2001 • 312 citations

Tick Histamine-Binding Proteins

1999 • 306 citations

Histamine regulates cytokine production in maturing dendritic cells, resulting in altered T cell polarization

2001 • 292 citations

Inverse agonism: pharmacological curiosity or potential therapeutic strategy?

1995 • 285 citations

Histamine H₁-Receptor Activation of Nuclear Factor-κB: Roles for Gβγ- and Gα_q/11-Subunits in Constitutive and Agonist-Mediated Signaling

2001 • 253 citations

Histamine Polarizes Human Dendritic Cells into Th2 Cell-Promoting Effector Dendritic Cells

2001 • 248 citations

Histamine induces leukocyte rolling in post-capillary venules. A P-selectin-mediated event.

1994 • 239 citations

Immune regulation by histamine

2002 • 234 citations

Does Medical Antireflux Therapy Improve Asthma in Asthmatics With Gastroesophageal Reflux?

1998 • 228 citations

Histamine inhibits the production of interleukin-12 through interaction with H2 receptors.

1998 • 214 citations

Inhibitory effect of cetirizine 2HCl on eosinophil migration in vivo

1987 • 199 citations

IDENTIFICATION OF A HISTAMINE H₄RECEPTOR ON HUMAN EOSINOPHILS—ROLE IN EOSINOPHIL CHEMOTAXIS

2002 • 194 citations

Histamine Induces CD86 Expression and Chemokine Production by Human Immature Dendritic Cells

2001 • 161 citations

Histamine H₄and H₂Receptors Control Histamine-Induced Interleukin-16 Release from Human CD8⁺T Cells

2002 • 159 citations

Histamine stimulates proliferation of airway smooth muscle and induces c-fos expression

1990 • 158 citations

Expression and function of histamine receptors in human monocyte-derived dendritic cells

2002 • 151 citations

Identification of Bphs , an Autoimmune Disease Locus, as Histamine Receptor H ₁

2002 • 149 citations

Premedication with antihistamines may enhance efficacy of specific-allergen immunotherapy

2001 • 145 citations

Histamine induces interleukin-8 secretion by endothelial cells

1994 • 143 citations

The Effects of the Immunologic Release of Histamine upon Human Lung Cyclic Nucleotide Levels and Prostaglandin Generation

1978 • 141 citations

Histamine Modulation of Eosinophil Migration

1977 • 128 citations

Classification and biological distribution of histamine receptor sub-types

1994 • 126 citations

Classification and biological distribution of histamine receptor sub-types

1975 • 122 citations

Defective Angiogenesis in the Inflammatory Granulation Tissue in Histidine Decarboxylase–deficient Mice but not in Mast Cell–deficient Mice

2002 • 119 citations

Histamine production during the anti-allograft response. Demonstration of a new lymphokine enhancing histamine synthesis

1981 • 118 citations

Importance of Histamine in the Cytokine Network in the Lung Through H2 and H3 Receptors: Stimulation of IL-10 Production

2000 • 114 citations

Novel insights into histamine H₂receptor biology

1997 • 112 citations

Augmentation of Antigen Receptor–mediated Responses by Histamine H1 Receptor Signaling

1999 • 109 citations

Functional Relationship between Mast Cells and C-Sensitive Nerve Fibres Evidenced by Histamine H3-Receptor Modulation in Rat Lung and Spleen

1994 • 102 citations

Histamine modulation of human neutrophil oxidative metabolism, locomotion, degranulation, and membrane potential changes.

1983 • 98 citations

Simultaneous induction of histidine and ornithine decarboxylases and changes in their product amines following the injection of escherichia coli lipopolysaccharide into mice

1982 • 98 citations

Histamine enhances interleukin (IL)-1-induced IL-1 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells. Comparison with IL-1 receptor antagonist.

1993 • 96 citations

Characteristics of histamine‐induced leukocyte rolling in the undisturbed microcirculation of the rat mesentery

1998 • 96 citations

Regulation of interleukin-10 secretion by histamine in TH2 cells and splenocytes

2001 • 94 citations

Comparative pharmacology of H1 antihistamines: clinical relevance

2002 • 91 citations

Histamine enhances TGF‐β1‐mediated suppression of Th2 responses

2003 • 90 citations

Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation

2001 • 89 citations

Expression and function of histamine receptors 1 and 2 on human monocyte-derived dendritic cells

2002 • 84 citations

Histamine-producing cell-stimulating activity. Interleukin 3 and granulocyte-macrophage colony-stimulating factor induce de novo synthesis of histidine decarboxylase in hemopoietic progenitor cells.

1987 • 83 citations

Histamine‐induced inhibition of neutrophil chemotaxis and T‐lymphocyte proliferation in man

1992 • 81 citations

Histamine stimulates inositol phosphate accumulation via the H1-receptor in cultured human endothelial cells

1987 • 75 citations

Antigen-independent Induction of Histamine Synthesis by Immunoglobulin E in Mouse Bone Marrow–derived Mast Cells

2002 • 74 citations

Novel β2-adrenergic receptor signaling pathways

2002 • 74 citations

Suppression by Azelastine Hydrochloride of NF-/.KAPPA.B Activation Involved in Generation of Cytokines and Nitric Oxide.

1997 • 71 citations

Histamine enhances interleukin (IL)-1-induced IL-6 gene expression and protein synthesis via H2 receptors in peripheral blood mononuclear cells

1994 • 71 citations

Leukotriene B₄mediates histamine induction of NF-κB and IL-8 in human bronchial epithelial cells

1998 • 63 citations

Regulation of histamine synthesis in mouse CD4+ and CD8+ T lymphocytes

1999 • 59 citations

Histamine influences the expression of the interleukin-6 receptor on human lymphoid, monocytoid and hepatoma cell lines

1991 • 53 citations

Effect of loratadine on nitrogen dioxide–induced changes in electrical resistance and release of inflammatory mediators from cultured human bronchial epithelial cells☆☆☆★

1999 • 52 citations

Orphan G-protein coupled receptors: novel drug targets for the pharmaceutical industry.

2000 • 50 citations

Regulatory effect of histamine H1 receptor antagonist on the expression of messenger RNA encoding CC chemokines in the human nasal mucosa

2001 • 48 citations

Effect of inhaled H1 and H2 receptor antagonist in normal and asthmatic subjects.

1980 • 47 citations

Regulation of histamine H₁ receptor coupling by dexamethasone in human cultured airway smooth muscle

1996 • 38 citations

Immunologic Effects of Cimetidine: Potential Uses

1987 • 36 citations

HISTAMINE INDUCED HOMOLOGOUS AND HETEROLOGOUS REGULATION OF HISTAMINE RECEPTOR SUBTYPE mRNA EXPRESSION IN CULTURED ENDOTHELIAL CELLS

1999 • 34 citations

Histamine content, synthesis and degradation in human nasal mucosa

1993 • 32 citations

Comparison of the effects of histamine H1- and H2-receptor agonists on large and small airways in normal and asthmatic subjects

1987 • 29 citations

Phosphoinositide Turnover

1987 • 27 citations

Possible role of histamine in pathogenesis of autoimmune diseases: Implications for immunotherapy with histamine-2 receptor antagonists

1992 • 23 citations

Cimetidine and a tamoxifen derivate reduce tumour formation in SCID mice xenotransplanted with a human melanoma cell line

2002 • 22 citations

Suppression of Gastric H2-Receptor Mediated Function in Patients with Bronchial Asthma and Ragweed Allergy

1986 • 17 citations

Cimetidine-induced augmentation of human lymphocyte blastogenesis: comparison with levamisole in mitogen stimulation.

1979 • 16 citations

Decrease in suppressor/cytotoxic T‐cells with histamine receptors in patients with chronic active hepatitis

1984 • 2 citations