Histamine enhances TGF‐β1‐mediated suppression of Th2 responses

TGF-β signalling from cell membrane to nucleus through SMAD proteins

1997 • 3,650 citations

Anesthesiology

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CREB: A Stimulus-Induced Transcription Factor Activated by A Diverse Array of Extracellular Signals

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Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

Allergy and Allergic Diseases

2001 • 1,349 citations

Identification and Functional Characterization of Human Cd4+Cd25+ T Cells with Regulatory Properties Isolated from Peripheral Blood

2001 • 1,293 citations

Modulation of Inflammation and Immunity by Cyclic AMP

1974 • 923 citations

Induction and mechanism of action of transforming growth factor‐β‐secreting Th3 regulatory cells

2001 • 856 citations

Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway

1999 • 800 citations

Molecular Cloning and Characterization of a Novel Type of Histamine Receptor Preferentially Expressed in Leukocytes

2000 • 609 citations

Distribution, properties, and functional characteristics of three classes of histamine receptor.

1990 • 579 citations

Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors

2001 • 578 citations

Identification and Functional Characterization of a Smad Binding Element (SBE) in the JunB Promoter That Acts as a Transforming Growth Factor-β, Activin, and Bone Morphogenetic Protein-inducible Enhancer

1998 • 562 citations

The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response

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A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA.

2000 • 455 citations

A mechanism of suppression of TGF–β/SMAD signaling by NF-κB/RelA

2000 • 397 citations

Activation of the Cooh-Terminal Src Kinase (Csk) by Camp-Dependent Protein Kinase Inhibits Signaling through the T Cell Receptor

2001 • 322 citations

The role of histamine in allergic diseases

1990 • 321 citations

Cloning, Expression, and Pharmacological Characterization of a Novel Human Histamine Receptor

2001 • 321 citations

Allergy and Allergic Diseases

2001 • 318 citations

Identification of Rat H₃Receptor Isoforms with Different Brain Expression and Signaling Properties

2001 • 284 citations

IL‐10‐induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy

1999 • 250 citations

CD4+ regulatory T cells

2001 • 241 citations

Trends in histamine research: new functions during immune responses and hematopoiesis

2002 • 236 citations

Transcript imaging of the development of human T helper cells using oligonucleotide arrays

2000 • 230 citations

Elevated bronchoalveolar lavage fluid histamine levels in allergic asthmatics are associated with methacholine bronchial hyperresponsiveness.

1987 • 221 citations

In Vitro Studies of Antigen-Induced Bronchospasm: Effect of Antihistamine and SRS-A Antagonist on Response of Sensitized Guinea Pig and Human Airways to Antigen

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Long‐term treatment with cetirizine of infants with atopic dermatitis: A multi‐country, double‐blind, randomized, placebo‐controlled trial (the ETAC^™trial) over 18 months

2002 • 189 citations

Premedication with antihistamines may enhance efficacy of specific-allergen immunotherapy

2001 • 145 citations

Novel insights into histamine H₂receptor biology

1997 • 112 citations

The role of histamine in allergic disease: re‐appraisal of its inflammatory potential

2002 • 95 citations

Histamine receptors: subclasses and specific ligands

1990 • 84 citations

Molecular properties and signalling pathways of the histamine H₁ receptor

1999 • 65 citations

Fexofenadine modulates T-cell function, preventing allergen-induced airway inflammation and hyperresponsiveness

2002 • 65 citations

Expression of cutaneous lymphocyte-associated antigen on human CD4+ and CD8+ Th2 cells

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Multiple protein kinases from human lymphocytes. Identification enzymes phosphorylating exogenous histon and casein

1975 • 52 citations

Histamine augments cytokine-stimulated IL-11 production by human lung fibroblasts.

1994 • 49 citations

Histone phosphatase and cyclic nucleotide-stimulated protein kinase from human lymphocytes

1972 • 31 citations

Role of tachykinin NK₁ and NK₂ receptors in allergen‐induced early and late asthmatic reactions, airway hyperresponsiveness, and airway inflammation in conscious, unrestrained guinea pigs

1999 • 31 citations

T-cell tolerance in allergic response

2002 • 27 citations

Involvement of protein kinase A in histamine-mediated inhibition of IL-2 mRNA expression in mouse splenocytes

1999 • 23 citations

TGF-β-mediated control of allergen-specific t-cell responses

2002 • 13 citations