Premedication with antihistamines may enhance efficacy of specific-allergen immunotherapy

Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures.

1995 • 533 citations

Diagnosis and Treatment of Insect Sensitivity

1966 • 417 citations

Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro.

1996 • 312 citations

Generation of Antigen-Specific Suppressor Cells during Allergy Desensitization

1980 • 307 citations

Insect venom immunotherapy induces interleukin‐10 production and a Th2‐to‐Th1 shift, and changes surface marker expression in venom‐allergic subjects

1997 • 287 citations

Immunotherapy with honeybee venom and yellow jacket venom is different regarding efficacy and safety

1992 • 280 citations

Long-term protection after stopping venom immunotherapy: Results of re-stings in 200 patients☆☆☆★★★

1998 • 194 citations

Position Paper: Immunotherapy with Hymenoptera venoms

1993 • 193 citations

Bee venom immunotherapy induces a shift in cytokine responses from a TH‐2 to a TH‐1 dominant pattern: comparison of rush and conventional immunotherapy

1995 • 191 citations

Histamine: an early messenger in inflammatory and immune reactions

1992 • 187 citations

The Hymenoptera venom study III: Safety of venom immunotherapy2

1990 • 179 citations

Efficacy of antihistamine pretreatment in the prevention of adverse reactions to Hymenoptera immunotherapy: A prospective, randomized, placebo-controlled trial☆☆☆★★★

1997 • 160 citations

Honeybee venom allergy: Results of a sting challenge 1 year after stopping successful venom immunotherapy in 86 patients

1991 • 147 citations

Antihistamine premedication in specific cluster immunotherapy: A double-blind, placebo-controlled study

1996 • 123 citations

Reduction of side‐effects from ultrarush immunotherapy with honeybee venom by pretreatment with fexofenadine:a double‐blind, placebo‐controlled trial

2000 • 116 citations

Reduction of side effects from rush‐immunotherapy with honey bee venom by pretreatment with terfenadine

1992 • 104 citations

Clinical correlation of the venom-specific IgG antibody level during maintenance venom immunotherapy

1992 • 100 citations

Venom Immunotherapy in Hymenoptera Sting Allergy

1983 • 70 citations

Allergic factors associated with the development of asthma and the influence of cetirizine in a double-blind, randomised, placebo-controlled trial: first results of ETAC. Early Treatment of the Atopic Child.

1998 • 31 citations

Specific inhibition of TH2‐type cytokine production from human peripheral T cells by terfenadine in vitro

1999 • 26 citations

Involvement of protein kinase A in histamine-mediated inhibition of IL-2 mRNA expression in mouse splenocytes

1999 • 23 citations

Reduction of side effects of specific immunotherapy by premedication with antihistaminics and reduction of maximal dosage to 50.000 SQ-U/ml.

1988 • 13 citations

CD28 expression is increased in venom allergic patients but is not modified by specific immunotherapy

1996 • 11 citations

Heterogeneous Effects of Histamine on Proliferation of Lung- and Blood-derived T-Cell Clones from Healthy and Asthmatic Persons

1993 • 8 citations

CD28 expression is increased in venom allergic patients but is not modified by specific immunotherapy

1996 • 2 citations