Regulation of interleukin-10 secretion by histamine in TH2 cells and splenocytes

Anti-inflammatory Actions of Glucocorticoids: Molecular Mechanisms

1998 • 1,516 citations

Histaminergic transmission in the mammalian brain

1991 • 948 citations

The Transcriptional Activity of NF-κB Is Regulated by the IκB-Associated PKAc Subunit through a Cyclic AMP–Independent Mechanism

1997 • 820 citations

A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis

1998 • 721 citations

IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes.

1995 • 420 citations

Interleukin-10 Inhibits Expression of Both Interferon – and Interferon γ– Induced Genes by Suppressing Tyrosine Phosphorylation of STAT1

1999 • 397 citations

Histamine Potently Suppresses Human IL-12 and Stimulates IL-10 Production via H2 Receptors

1998 • 372 citations

Role of cyclic AMP response element-binding protein in cyclic AMP inhibition of NF-kappaB-mediated transcription.

1997 • 320 citations

IL‐10‐induced anergy in peripheral T cell and reactivation by microenvironmental cytokines: two key steps in specific immunotherapy

1999 • 250 citations

Interleukin-10 and Transforming Growth Factor- β Promoter Polymorphisms in Allergies and Asthma

1998 • 250 citations

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1997 • 226 citations

Stat3 Recruitment by Two Distinct Ligand-induced, Tyrosine-phosphorylated Docking Sites in the Interleukin-10 Receptor Intracellular Domain

1996 • 211 citations

Location of cAMP-Dependent Protein Kinase Type I with the TCR-CD3 Complex

1994 • 200 citations

Anti-inflammatory activities of cAMP-elevating agents: enhancement of IL-10 synthesis and concurrent suppression of TNF production

1998 • 185 citations

IL‐10 induces DNA binding activity of three STAT proteins (Stat1, Stat3, and Stat5) and their distinct combinatorial assembly in the promoters of selected genes

1996 • 170 citations

JAK3, STAT, and MAPK Signaling Pathways as Novel Molecular Targets for the Tyrphostin AG-490 Regulation of IL-2-Mediated T Cell Response

1999 • 164 citations

VIP and PACAP inhibit IL-12 production in LPS-stimulated macrophages. Subsequent effect on IFNγ synthesis by T cells

1999 • 162 citations

Interleukin (IL)-10 inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells.

1996 • 160 citations

T CELL SUBSETS AND CYTOKINES IN ALLERGIC AND NON-ALLERGIC CHILDREN. I. ANALYSIS OF IL-4, IFN-γ AND IL-13 mRNA EXPRESSION AND PROTEIN PRODUCTION

1997 • 152 citations

Differential regulation of IFN‐γ, IL‐10 and inducible nitric oxide synthase in human T cells by cyclic AMP‐dependent signal transduction pathway

1997 • 124 citations

Cofactors are essential for stem cell factor-dependent growth and maturation of mast cell progenitors: comparative effects of interleukin- 3 (IL-3), IL-4, IL-10, and fibroblasts

1995 • 118 citations

Importance of Histamine in the Cytokine Network in the Lung Through H2 and H3 Receptors: Stimulation of IL-10 Production

2000 • 114 citations

Tyrphostin AG-490 inhibits cytokine-mediated JAK3/STAT5a/b signal transduction and cellular proliferation of antigen-activated human T cells

1999 • 110 citations

Augmentation of Antigen Receptor–mediated Responses by Histamine H1 Receptor Signaling

1999 • 109 citations

Different modulation by histamine of IL-4 and interferon-gamma (IFN-γ) release according to the phenotype of human Th0, Th1 and Th2 clones

1997 • 77 citations

Differential regulation of mast cell function by IL-10 and stem cell factor.

1997 • 76 citations

Activation of Protein Kinase A Inhibits Interferon Induction of the Jak/Stat Pathway in U266 Cells

1996 • 72 citations

Alveolar macrophage interleukin (IL)‐10 and IL‐12 production in atopic asthma

1998 • 69 citations

NK cell‐mediated killing of AML blasts: role of histamine, monocytes and reactive oxygen metabolites

1996 • 68 citations

T CELL SUBSETS AND CYTOKINES IN ALLERGIC AND NON-ALLERGIC CHILDREN. II. ANALYSIS OF IL-5 AND IL-10 mRNA EXPRESSION AND PROTEIN PRODUCTION

1997 • 59 citations

IL-4 Enhances IL-10 Gene Expression in Murine Th2 Cells in the Absence of TCR Engagement

1999 • 56 citations

Histamine type I (H1) receptor radioligand binding studies on normal T cell subsets, B cells, and monocytes.

1986 • 51 citations

Histamine Affects Interleukin-4, Interleukin-5, and Interferon- γ Production by Human T Cell Clones from the Airways and Blood

1998 • 50 citations

Histamine modulates the production of interferon-γ and interleukin-2 by mitogen-activated human mononuclear blood cells

1985 • 48 citations

Coadministration of IL-12 or IL-10 Expression Cassettes Drives Immune Responses Toward a Thl Phenotype

1998 • 46 citations

Adrenaline enhances LPS-induced IL-10 synthesis: evidence for protein kinase A-mediated pathway

1998 • 44 citations

Factors affecting the cytokine production of human T cells stimulated by different modes of activation

1996 • 38 citations

Activation of type I protein kinase A during receptor-mediated human T lymphocyte activation.

1996 • 34 citations

Diminished IL-10 production in subjects with allergy after infection with influenza A virus

1999 • 31 citations

Histamine increases anti-CD3 induced IL-5 production of TH2-type T cells via histamine H2-receptors

1994 • 29 citations

Dual Control of Human Interleukin-2 and Interferon-γ Gene Expression by Histamine: Activation and Suppression

1996 • 27 citations

Cytokines and their receptors as therapeutic targets in asthma.

1998 • 26 citations

Involvement of protein kinase A in histamine-mediated inhibition of IL-2 mRNA expression in mouse splenocytes

1999 • 23 citations

Protein kinase A inhibitors reverse histamine-mediated regulation of IL-5 secretion

1998 • 22 citations

Histamine H2 receptor activity and histamine metabolism in human U-937 monocyte-like cells and human peripheral monocytes

1986 • 22 citations

Histamine H2 receptors and histidine decarboxylase in normal and leukemic human monocytes and macrophages

1994 • 22 citations

Characterization of histamine H1 binding sites on human T lymphocytes by means of 125I-iodobolpyramine. Preferential expression of H1 receptors on CD8 T lymphocytes.

1990 • 18 citations

Cytokines involved in the downregulation of allergic airway inflammation

1997 • 17 citations

Dysregulation of monocyte differentiation in asthmatic subjects is reversed by IL‐10

1998 • 12 citations

Effect of bronchial allergen challenge on in vitro cytokine release by peripheral blood mononuclear cells of atopic patients

1998 • 9 citations

Difference in Signal Transduction for IL-10 and IFN-γ Production in a CD8+T Cell Clone

1996 • 6 citations

Increase in intracellular calcium induced by stimulating histamine H1 receptors in macrophage-like P388D1 cells

1991 • 4 citations