Expression of Bcl-2 and Bax in oligodendrogliomas and their relationship to apoptosis

p53, the Cellular Gatekeeper for Growth and Division

1997 • 7,621 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

Bid, a Bcl2 Interacting Protein, Mediates Cytochrome c Release from Mitochondria in Response to Activation of Cell Surface Death Receptors

1998 • 3,603 citations

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1997 • 1,768 citations

The p53 pathway

1999 • 1,322 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 1,078 citations

Bcl-2 initiates a new category of oncogenes: regulators of cell death

1992 • 860 citations

Programmed cell death: Apoptosis and oncogenesis

1991 • 856 citations

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

1996 • 746 citations

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

1997 • 648 citations

Successful chemotherapy for recurrent malignant oligodendroglioma

1988 • 346 citations

p53 in signaling checkpoint arrest or apoptosis

1996 • 336 citations

Apoptosis and therapy

1999 • 294 citations

Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation.

1995 • 258 citations

New members of the Bcl-2 family and their protein partners

1996 • 248 citations

p53 mutations in nonastrocytic human brain tumors.

1991 • 225 citations

Predicting chemoresistance in human malignant glioma cells: The role of molecular genetic analyses

1998 • 171 citations

Clinicopathologic correlations in the oligodendroglioma

1987 • 145 citations

Immunohistochemical analysis of Bcl-2, Bcl-X, Mcl-1, and Bax in tumors of central and peripheral nervous system origin.

1997 • 145 citations

Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.

1989 • 138 citations

Oligodendroglioma. Histologic Evaluation and Prognosis

1986 • 130 citations

Tyramine Amplification Technique in Routine Immunohistochemistry

1997 • 110 citations

Apoptosis and cell proliferation in human neuroepithelial tumors

1995 • 96 citations

Expression of neuronal markers in oligodendrogliomas: an immunohistochemical study

1998 • 89 citations

p53 and Brain Tumors: From Gene Mutations to Gene Therapy

1998 • 82 citations

BCL-2 family protein expression in human malignant glioma: a clinical-pathological correlative study

1998 • 78 citations

bcl-2 protein expression in tumors of the central nervous system

1994 • 76 citations

Association ofp53 gene mutation with decreased chemosensitivity in human malignant gliomas

1996 • 74 citations

Apoptosis in cerebral astrocytic tumours and its relationship to expression of the bcl‐2 and p53 proteins

1995 • 60 citations

Oligodendroglioma: an analysis of 42 cases.

1987 • 55 citations

Apoptosis in human primary brain tumours: actions of arachidonic acid

1998 • 55 citations

A multivariate analysis of tumour biological factors predicting response to cytotoxic treatment in advanced breast cancer

1998 • 53 citations

Bcl-2 distribution in neuroepithelial tumors: an immunohistochemical study

1996 • 48 citations

bcl-2 protein expression in astrocytomas in relation to patient survival and p53 gene status

1997 • 47 citations

Apoptosis is inversely related to bcl‐2 but not to bax expression in salivary gland tumours

1998 • 47 citations

Detection of DNA strand breaks associated with apoptosis in human brain tumors

1995 • 46 citations

Is Necrosis Helpful in the Grading of Gliomas? Editorial Opinion

1992 • 46 citations

Proliferation and cell death in oligodendrogliomas.

1998 • 45 citations

Proteolytic cleavage during chemotherapy-induced apoptosis

1996 • 35 citations

Role of apoptosis in the prognosis of oligodendrogliomas

1997 • 30 citations

Mutation of the p53 gene in human astrocytic tumours correlates with increased resistance to DNA-damaging agents but not to anti-microtubule anti-cancer agents

1998 • 29 citations

Advances in brain tumor chemosensitivity

1998 • 14 citations