Apoptosis is inversely related to bcl‐2 but not to bax expression in salivary gland tumours

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

Apoptosis. Its significance in cancer and cancer Therapy

1994 • 2,148 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Involvement of the bcl -2 Gene in Human Follicular Lymphoma

1985 • 1,797 citations

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1995 • 1,552 citations

BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax

1994 • 1,303 citations

A new method to detect apoptosis in paraffin sections: in situ end-labeling of fragmented DNA.

1993 • 823 citations

Interactions among members of the Bcl-2 protein family analyzed with a yeast two-hybrid system.

1994 • 590 citations

Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.

1995 • 317 citations

Apoptosis and immunohistochemicalbcl-2 expression in colorectal adenomas and carcinomas: Aspects of carcinogenesis and prognostic significance

1996 • 224 citations

Enhanced apoptosis predicts shortened survival in non-small cell lung carcinoma

1996 • 154 citations

bcl-2 in cancer, development and apoptosis

1994 • 128 citations

Hepatocellular carcinomas with a high proliferation index and a low degree of apoptosis and necrosis are associated with a shortened survival

1996 • 109 citations

Apoptosis in operated small cell lung carcinoma is inversely related to tumour necrosis and p53 immunoreactivity

1997 • 50 citations

Expression of bcl-2 in Salivary Glands and Salivary Gland Adenomas

1995 • 39 citations

Genetics and limb development

1996 • 35 citations

Extent of apoptosis in relation to p53 and bcl-2 expression in germ cell tumors

1996 • 24 citations