Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Cell Cycle Control and Cancer

1994 • 2,575 citations

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1996 • 2,304 citations

p21 is necessary for the p53-mediated G1 arrest in human cancer cells.

1995 • 1,193 citations

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

1994 • 1,165 citations

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage.

1995 • 1,114 citations

Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

1993 • 997 citations

Creative blocks: cell-cycle checkpoints and feedback controls

1992 • 686 citations

A p53-Dependent Mouse Spindle Checkpoint

1995 • 668 citations

Ordering S phase and M phase in the cell cycle

1994 • 596 citations

Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues.

1995 • 593 citations

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA

1995 • 561 citations

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1995 • 552 citations

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

1994 • 496 citations

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice.

1993 • 471 citations

Human cytogenetics : a practical approach

1986 • 361 citations

Human Cytogenetics: A Practical Approach

1993 • 285 citations

Rules to replicate by

1994 • 252 citations

Cell line-specific differences in the control of cell cycle progression in the absence of mitosis.

1990 • 222 citations

Cytotoxic effects of cell cycle phase specific agents: result of cell cycle perturbation.

1990 • 144 citations

Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes

1995 • 126 citations

Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer.

1995 • 104 citations

Stabilised p53 facilitates aneuploid clonal divergence in colorectal cancer.

1993 • 102 citations

Specific metaphase and interphase detection of the breakpoint region in 8q24 of burkitt lymphoma cells by triple‐color fluorescence in situ hybridization

1992 • 97 citations

Exercising self-restraint: Discouraging illicit acts of S and M in eukaryotes

1993 • 83 citations

Microwave fixation: Understanding the variables to achieve rapid reproducible results

1995 • 76 citations

Large-scale isolation of human 1p36-specific P1 clones and their use for fluorescence in situ hybridization

1994 • 13 citations