Tracing lymphopoiesis with the aid of a pTα-controlled reporter gene

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

1997 • 2,205 citations

Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

1999 • 1,392 citations

B Cell Development Pathways

2001 • 1,185 citations

The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype

1994 • 1,109 citations

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

2001 • 1,017 citations

Notch1 Expression in Early Lymphopoiesis Influences B versus T Lineage Determination

1999 • 956 citations

Stem and Progenitor Cells: Origins, Phenotypes, Lineage Commitments, and Transdifferentiations

2001 • 928 citations

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1994 • 807 citations

Upregulation of Flt3 Expression within the Bone Marrow Lin−Sca1+c-kit+ Stem Cell Compartment Is Accompanied by Loss of Self-Renewal Capacity

2001 • 691 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

Analysis and Expression of a Cloned Pre-T Cell Receptor Gene

1994 • 410 citations

Notch 1–Deficient Common Lymphoid Precursors Adopt a B Cell Fate in the Thymus

2001 • 392 citations

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

1999 • 372 citations

Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation

2001 • 348 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

Coordinate Regulation of B Cell Differentiation by the Transcription Factors EBF and E2A

1999 • 334 citations

A novel disulfide-linked heterodimer on pre—T cells consists of the T cell receptor β chain and a 33 kd glycoprotein

1993 • 333 citations

Haematopoietic cell-fate decisions, chromatin regulation and ikaros

2002 • 324 citations

Notch1 Signaling Promotes the Maturation of CD4 and CD8 SP Thymocytes

2000 • 317 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors.

1996 • 236 citations

Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.

1993 • 233 citations

Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway

2002 • 204 citations

Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells

2001 • 182 citations

Commitment of Common T/Natural Killer (Nk) Progenitors to Unipotent T and Nk Progenitors in the Murine Fetal Thymus Revealed by a Single Progenitor Assay

1999 • 169 citations

RAG2:GFP Knockin Mice Reveal Novel Aspects of RAG2 Expression in Primary and Peripheral Lymphoid Tissues

1999 • 167 citations

Role of PU.1 in Hematopoiesis

1998 • 159 citations

Expression of pT mRNA in a Committed Dendritic Cell Precursor in the Human Thymus

1999 • 153 citations

Coordinate Regulation of RAG1 and RAG2 by Cell Type-Specific DNA Elements 5' of RAG2

1999 • 145 citations

Functional Assessment of Precursors from Murine Bone Marrow Suggests a Sequence of Early B Lineage Differentiation Events

2000 • 130 citations

Intra‐ and extra‐thymic expression of the pre‐T cell receptor α gene

1995 • 109 citations

On the Role of the Pre–T Cell Receptor in αβ versus γδ T Lineage Commitment

1998 • 96 citations

Extrathymic maturation of alpha beta T cells from hemopoietic stem cells.

1995 • 90 citations

Identification of a Committed T Cell Precursor Population in Adult Human Peripheral Blood

1997 • 72 citations

Mouse pre-immunocytes as non-proliferating multipotent precursors of macrophages, interferon-producing cells, CD8α+ and CD8α- dendritic cells

2001 • 70 citations

Expression of functional interleukin-2 receptors in human light chain/Tac ransgenic mice

1988 • 70 citations

Emergence of T Cell Progenitors Without B Cell or Myeloid Differentiation Potential at the Earliest Stage of Hematopoiesis in the Murine Fetal Liver

1999 • 68 citations

A Transgenic Marker for Mouse B Lymphoid Precursors

1997 • 58 citations

The Upstream Enhancer Is Necessary and Sufficient for the Expression of the Pre-T Cell Receptor α Gene in Immature T Lymphocytes

2001 • 53 citations

Expression of the Mouse Pre-T Cell Receptor α Gene Is Controlled by an Upstream Region Containing a Transcriptional Enhancer

1999 • 53 citations

Characterization of T cell precursor activity in the murine fetal thymus: evidence for an input of T cell precursors between days 12 and 14 of gestation

2000 • 47 citations

Characterization of T cell precursor activity in the murine fetal thymus: evidence for an input of T cell precursors between days 12 and 14 of gestation

2000 • 24 citations