Commitment of Common T/Natural Killer (Nk) Progenitors to Unipotent T and Nk Progenitors in the Murine Fetal Thymus Revealed by a Single Progenitor Assay

Biology of Natural Killer Cells

1989 • 2,970 citations

IL-15 Receptor Maintains Lymphoid Homeostasis by Supporting Lymphocyte Homing and Proliferation

1998 • 1,293 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

1995 • 881 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. II. Characterization of effector cells

1975 • 844 citations

Development of peripheral lymphoid organs and natural killer cells depends on the helix–loop–helix inhibitor Id2

1999 • 841 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Developing Lymph Nodes Collect CD4 + CD3 − LTβ + Cells That Can Differentiate to APC, NK Cells, and Follicular Cells but Not T or B Cells

1997 • 654 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

The identification in adult bone marrow of pluripotent and restricted stem cells of the myeloid and lymphoid systems

1977 • 563 citations

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice

1995 • 493 citations

Early T Lymphocyte Progenitors

1996 • 473 citations

Abnormal Development of Intestinal Intraepithelial Lymphocytes and Peripheral Natural Killer Cells in Mice Lacking the IL-2 Receptor β Chain

1997 • 359 citations

Requirement for IRF-1 in the microenvironment supporting development of natural killer cells

1998 • 352 citations

The Ets-1 Transcription Factor Is Required for the Development of Natural Killer Cells in Mice

1998 • 351 citations

IL-7 receptor α+ CD3– cells in the embryonic intestine induces the organizing center of Peyer's patches

1999 • 289 citations

Identification of a common T/natural killer cell progenitor in human fetal thymus.

1994 • 280 citations

Inhibition of T Cell and Promotion of Natural Killer Cell Development by the Dominant Negative Helix Loop Helix Factor Id3

1997 • 279 citations

Mechanism of Cytotoxicity by Natural Killer (NK) Cells

1986 • 272 citations

A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells

1992 • 264 citations

Characterization of c-kit positive intrathymic stem cells that are restricted to lymphoid differentiation.

1993 • 233 citations

A block in both early T lymphocyte and natural killer cell development in transgenic mice with high-copy numbers of the human CD3E gene.

1994 • 233 citations

The developmental relationship between NK cells and T cells

1992 • 183 citations

Cell-mediated cytotoxicity

1989 • 165 citations

T-cell lineage commitment and cytokine responses of thymic progenitors

1995 • 164 citations

Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells.

1996 • 162 citations

Identification of a Novel Developmental Stage Marking Lineage Commitment of Progenitor Thymocytes

1997 • 146 citations

Direct evidence for the commitment of hematopoietic stem cells to T, B and myeloid lineages in murine fetal liver

1997 • 144 citations

Requirement for TNF-α and IL-1α in Fetal Thymocyte Commitment and Differentiation

1995 • 135 citations

Natural killer cell differentiation: insights from knockout and transgenic mouse models and in vitro systems

1998 • 131 citations

Human natural killer cell committed thymocytes and their relation to the T cell lineage.

1993 • 107 citations

Requirement for the Thymus in αβ T Lymphocyte Lineage Commitment

1998 • 99 citations

Transcriptional control of lymphoid development: lessons from gene targeting

1996 • 97 citations

Presence of progenitors restricted to T, B, or myeloid lineage, but absence of multipotent stem cells, in the murine fetal thymus.

1998 • 84 citations

Cutting Edge: Presence of Progenitors Restricted to T, B, or Myeloid Lineage, but Absence of Multipotent Stem Cells, in the Murine Fetal Thymus

1998 • 71 citations

Expression of genes encoding the pre-TCR and CD3 complex during thymus development

1995 • 71 citations

Early stages in human and mouse T-cell development

1994 • 63 citations

In vitro development of B cells and macrophages from early mouse fetal thymocytes

1994 • 62 citations

Pathways from hematopoietic stem cells to thymocytes

1995 • 59 citations

Natural killer cell development and function precede alpha beta T cell differentiation in mouse fetal thymic ontogeny.

1998 • 56 citations

Isolation of the most immature population of murine fetal thymocytes that includes progenitors capable of generating T, B, and myeloid cells.

1996 • 54 citations

Lineage commitment and differentiation of T and natural killer lymphocytes in the fetal mouse

1998 • 54 citations

Development of T cell receptor αβ‐bearing T cells in the submersion organ culture of murine fetal thymus at high oxygen concentration

1993 • 52 citations

Ontogeny of Nk-1+ natural killer cells. I. Promotion of Nk-1+ cells in fetal, baby, and old mice.

1982 • 50 citations

Natural Killer Cell Development and Function Precede αβ T Cell Differentiation in Mouse Fetal Thymic Ontogeny

1998 • 48 citations

Clonal Proliferation and Cytokine Requirement of Murine Progenitors for Natural Killer Cells

1997 • 21 citations

Lineage relationships of the fetal thymocyte subset that expresses the β chain of the interleukin‐2 receptor

1993 • 15 citations