Nadrin, a Novel Neuron-specific GTPase-activating Protein Involved in Regulated Exocytosis

Basic local alignment search tool

1990 • 87,358 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

1993 • 7,941 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

1989 • 3,067 citations

Protein modules and signalling networks

1995 • 2,447 citations

Proteins regulating Ras and its relatives

1993 • 1,930 citations

PEST sequences and regulation by proteolysis

1996 • 1,606 citations

Prediction of the Coding Sequences of Unidentified Human Genes. IX. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

1998 • 848 citations

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

1997 • 802 citations

[30] Prediction and analysis of coiled-coil structures

1996 • 574 citations

Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cells.

1995 • 436 citations

Structural Organization of the Synaptic Exocytosis Core Complex

1997 • 352 citations

Synaptic vesicle biogenesis, docking, and fusion: a molecular description

1996 • 349 citations

Molecular cloning of cDNAs encoding the GAP-associated protein p190: Implications for a signaling pathway from ras to the nucleus

1992 • 343 citations

Chromaffin cell cortical actin network dynamics control the size of the release-ready vesicle pool and the initial rate of exocytosis

1995 • 341 citations

The organization of cytoplasm at the presynaptic active zone of a central nervous system synapse

1988 • 340 citations

Trinucleotide Repeats in Neurogenetic Disorders

1996 • 323 citations

Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis

1996 • 260 citations

Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP

1997 • 252 citations

Cloning of ligand targets: Systematic isolation of SH3 domain-containing proteins

1996 • 224 citations

Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin.

1991 • 223 citations

Nuclear localization signals overlap DNA- or RNA-binding domains in nucleic acid-binding proteins

1995 • 211 citations

GENETICS OF SYNAPTIC VESICLE FUNCTION: Toward the Complete Functional Anatomy of an Organelle

1999 • 183 citations

A novel type of myosin implicated in signalling by rho family GTPases.

1995 • 176 citations

Prediction of the Coding Sequences of Unidentified Human Genes. X. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

1998 • 160 citations

Cytoskeleton dynamics during neurotransmitter release

1993 • 159 citations

The GTPase-Activating Protein n-Chimaerin Cooperates with Rac1 and Cdc42Hs To Induce the Formation of Lamellipodia and Filopodia

1996 • 152 citations

Actin filament organization in activated mast cells is regulated by heterotrimeric and small GTP-binding proteins.

1994 • 135 citations

Transient transfection studies of secretion in bovine chromaffin cells and PC12 cells. Generation of kainate-sensitive chromaffin cells

1993 • 133 citations

The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways.

1996 • 130 citations

Cloning and expression of a human CDC42 GTPase-activating protein reveals a functional SH3-binding domain.

1993 • 123 citations

Expression of a conserved cell-type-specific protein in nerve terminals coincides with synaptogenesis.

1991 • 114 citations

Germ cell beta-chimaerin, a new GTPase-activating protein for p21rac, is specifically expressed during the acrosomal assembly stage in rat testis.

1993 • 104 citations

Post-Transcriptional Regulation of Synaptic Vesicle Protein Expression and the Developmental Control of Synaptic Vesicle Formation

1997 • 98 citations

The Rat Myosin myr 5 Is a GTPase-activating Protein for Rho In Vivo: Essential Role of Arginine 1695

1997 • 92 citations

Overexpression of a Novel Rho Family GTPase, RacC, Induces Unusual Actin-based Structures and Positively Affects Phagocytosis inDictyostelium discoideum

1998 • 90 citations

Induction of Exocytosis from Permeabilized Mast Cells by the Guanosine Triphosphatases Rac and Cdc42

1998 • 89 citations

Identification of a Potential Effector Pathway for the Trimeric Go Protein Associated with Secretory Granules

1998 • 88 citations

The Function of the p190 Rho GTPase-activating Protein Is Controlled by Its N-terminal GTP Binding Domain

1998 • 83 citations

Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.

1993 • 81 citations

Recombinant Scinderin Enhances Exocytosis, an Effect Blocked by Two Scinderin-Derived Actin-Binding Peptides and PIP2

1996 • 80 citations

Actin disassembles reversibly during electrically induced recycling of synaptic vesicles in cultured neurons

1998 • 78 citations

Protein kinase C and Ca2+/calmodulin-dependent protein kinase II phosphorylate a novel 58-kDa protein in synaptic vesicles

1991 • 78 citations

Doc2 Enhances Ca2+-dependent Exocytosis from PC12 Cells

1996 • 75 citations

Human ABR encodes a protein with GAPrac activity and homology to the DBL nucleotide exchange factor domain

1993 • 70 citations

3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts.

1995 • 68 citations

Characterization of anti-actin antibodies and their use in immunocytochemical studies on the localization of actin in adrenal chromaffin cells in culture

1981 • 67 citations

Trimeric G Proteins Control Exocytosis in Chromaffin Cells

1997 • 64 citations

Purification and identification of FOAD-II, a cytosolic protein that regulates secretion in streptolysin-O permeabilized mast cells, as a rac/rhoGDI complex.

1996 • 58 citations

Dissection of stages in exocytosis in the adrenal chromaffin cell with use of trifluoperazine

1982 • 58 citations

Possible Involvement of Phosphatidylinositol 3‐Kinase in Regulated Exocytosis: Studies in Chromaffin Cells with Inhibitor LY294002

1998 • 50 citations

Involvement of Rho and Rac small G proteins and Rho GDI in Ca²⁺‐dependent exocytosis from PC12 cells

1996 • 50 citations

Changes in mobility of synaptic vesicles with assembly and disassembly of actin network

1995 • 40 citations

Patterns of Presynaptic Gene Expression Define Two Stages of Synaptic Differentiation

1995 • 37 citations

Localization of the Phosphatidylserine-Binding Site of Glyceraldehyde-3-Phosphate Dehydrogenase Responsible for Membrane Fusion

1997 • 32 citations

Secretory vesicle pools and rate and kinetics of single vesicle exocytosis in neurosecretory cells.

1997 • 19 citations

Innervation and target tissue interactions induce Rab-GDP dissociation inhibitor (GDI) expression during peripheral synapse formation in developing chick ciliary ganglion neurons in situ.

1998 • 15 citations

Innervation and Target Tissue Interactions Induce Rab-GDP Dissociation Inhibitor (GDI) Expression during Peripheral Synapse Formation in Developing Chick Ciliary Ganglion NeuronsIn Situ

1998 • 13 citations

A Monoclonal Antibody, 3A10, Recognizes a Specific Amino Acid Sequence Present on a Series of Developmentally Expressed Brain Proteins

1999 • 12 citations