Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain.

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1992 • 3,628 citations

Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase

1991 • 1,779 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

Structural organization of the bcr gene and its role in the Ph′ translocation

1985 • 920 citations

CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae.

1990 • 605 citations

Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity.

1990 • 560 citations

Bcr encodes a GTPase-activating protein for p21rac

1991 • 474 citations

Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharomyces cerevisiae.

1991 • 442 citations

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbloncogene product

1991 • 424 citations

Multicopy suppression of the cdc24 budding defect in yeast by CDC42 and three newly identified genes including the ras-related gene RSR1.

1989 • 406 citations

Association between GTPase activators for Rho and Ras families

1992 • 322 citations

Molecular cloning and characterization of a novel type of regulatory protein (GDI) for the rho proteins, ras p21-like small GTP-binding proteins.

1990 • 314 citations

Purification and characterization from bovine brain cytosol of a novel regulatory protein inhibiting the dissociation of GDP from and the subsequent binding of GTP to rhoB p20, a ras p21-like GTP-binding protein.

1990 • 277 citations

The BCR gene encodes a novel serine/threonine kinase activity within a single exon

1991 • 273 citations

Roles of the CDC24 gene product in cellular morphogenesis during the Saccharomyces cerevisiae cell cycle.

1981 • 264 citations

Identification of distinct cytoplasmic targets for ras/R-ras and rho regulatory proteins

1989 • 258 citations

Development of cell polarity in budding yeast

1991 • 252 citations

Reconstitution of catecholamine-stimulated guanosine triphosphatase activity

1983 • 213 citations

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42.

1990 • 204 citations

The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein

1992 • 175 citations

A GDP Dissociation Inhibitor That Serves as a GTPase Inhibitor for the Ras-Like Protein CDC42Hs

1992 • 164 citations

A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

1989 • 161 citations

Signal transduction through small GTPases—A tale of two GAPs

1992 • 137 citations

Both stimulatory and inhibitory exchange proteins, smg GDS and rho GDI, are active on multiple small GTP-binding proteins

1992 • 116 citations

Identification of the human platelet GTPase activating protein for the CDC42Hs protein.

1991 • 71 citations

Purification of GTPase-activating protein specific for the rho gene products.

1991 • 51 citations

Expression of epidermal growth factor receptor sequences as E. coli fusion proteins: Applications in the study of tyrosine kinase function

1990 • 33 citations