Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing–remitting multiple sclerosis treated with interferon beta

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Matrix Metalloproteinases

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Matrix metalloproteinases and diseases of the CNS

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Targeting leukocyte MMPs and transmigration

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Multiple Sclerosis

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Interferon beta‐1b inhibits gelatinase secretion and in vitro migration of human T cells: A possible mechanism for treatment efficacy in multiple sclerosis

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Inhibition of autoimmune encephalomyelitis by a tetracycline

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Gelatinase in the cerebrospinal fluid of patients with multiple sclerosis and other inflammatory neurological disorders

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Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis

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Matrix Metalloproteinase-9/Gelatinase B Is Required for Process Outgrowth by Oligodendrocytes

1999 • 268 citations

Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system

1999 • 268 citations

Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis

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Matrix metalloproteinase-9 (gelatinase B) is selectively elevated in CSF during relapses and stable phases of multiple sclerosis

1998 • 248 citations

Differential mechanisms of action of interferon-β and glatiramer acetate in MS

2002 • 238 citations

Serum MMP-9 and TIMP-1 levels are related to MRI activity in relapsing multiple sclerosis

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Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-α inhibitor

1997 • 205 citations

Serum gelatinase B, TIMP-1 and TIMP-2 levels in multiple sclerosis

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Serum MMP-2 and MMP-9 are elevated in different multiple sclerosis subtypes

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The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system

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Matrix Metalloproteinases and Neuroinflammation in Multiple Sclerosis

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Molecular pathogenesis of multiple sclerosis

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Functional roles and therapeutic targeting of gelatinase B and chemokines in multiple sclerosis

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Intrathecal synthesis of matrix metalloproteinase-9 in patients with multiple sclerosis: implication for pathogenesis

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IFNβ lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS

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Expression of matrix metalloproteinase-9 and its inhibitors in mononuclear blood cells of patients with multiple sclerosis

1999 • 95 citations

Gelatinase B/matrix metalloproteinase‐9 cleaves interferon‐β and is a target for immunotherapy

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Matrix metalloproteinase-9 (MMP-9) in human cerebrospinal fluid (CSF): elevated levels are primarily related to CSF cell count

2000 • 84 citations

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2000 • 84 citations

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in cerebrospinal fluid differ in multiple sclerosis and Devic's neuromyelitis optica

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Metalloproteinases and their Tissue Inhibitors in Multiple Sclerosis

1999 • 63 citations

Interferon-?-1 b decreased matrix metalloproteinase-9 serum levels in primary progressive multiple sclerosis

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Effect of interferon �-1a on serum matrix metalloproteinase?9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in relapsing remitting multiple sclerosis patients

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The pathogenesis and basis for treatment in multiple sclerosis

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IFN-β1a May Increase Serum Levels of TIMP-1 in Patients with Relapsing-Remitting Multiple Sclerosis

2001 • 31 citations

Gelatinase B in multiple sclerosis and experimental autoimmune encephalomyelitis.

1999 • 22 citations

Serum gelatinase B/MMP-9 in primary progressive multiple sclerosis patients treated with interferon-beta-1a

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