Identification of the Anti-proliferative Protein Tob as a MAPK Substrate

Mammalian MAP kinase signalling cascades

2001 • 5,041 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Signal Transduction by the JNK Group of MAP Kinases

2000 • 4,096 citations

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

2001 • 3,295 citations

Mitogen-activated protein kinase pathways

1997 • 2,513 citations

Mitogen-Activated Protein Kinases: Specific Messages from Ubiquitous Messengers

1999 • 1,593 citations

Regulation of transcription by MAP kinase cascades

1996 • 1,330 citations

The MAP kinase cascade is essential for diverse signal transduction pathways

1993 • 1,091 citations

Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF

1999 • 1,068 citations

A conserved docking motif in MAP kinases common to substrates, activators and regulators

2000 • 801 citations

Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6

1991 • 442 citations

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1999 • 427 citations

Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

1996 • 416 citations

Negative Regulation of BMP/Smad Signaling by Tob in Osteoblasts

2000 • 326 citations

BTG1, a member of a new family of antiproliferative genes.

1992 • 298 citations

The mitogen-activated protein kinase activator

1992 • 285 citations

Identification of an Extracellular Signal-regulated Kinase (ERK) Docking Site in Ribosomal S6 Kinase, a Sequence Critical for Activation by ERK in Vivo

1999 • 281 citations

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

2001 • 270 citations

CCR4, a 3′-5′ poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase

2002 • 248 citations

Arrest of G₁-S Progression by the p53-Inducible Gene PC3 Is Rb Dependent and Relies on the Inhibition of Cyclin D1 Transcription

2000 • 226 citations

Conditionally Oncogenic Forms of the A-Raf and B-Raf Protein Kinases Display Different Biological and Biochemical Properties in NIH 3T3 Cells

1995 • 222 citations

The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively

1998 • 207 citations

Tob, a novel protein that interacts with p185erbB2, is associated with anti-proliferative activity.

1996 • 190 citations

A MAP kinase docking site is required for phosphorylation and activation of p90rsk/MAPKAP kinase-1

1999 • 157 citations

Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases

1999 • 139 citations

Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation

2002 • 137 citations

ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system

1998 • 107 citations

Genetic Evidence Supports a Role for the Yeast CCR4-NOT Complex in Transcriptional Elongation

2001 • 83 citations

Functional Interaction of CCR4-NOT Proteins With TATAA-Binding Protein (TBP) and Its Associated Factors in Yeast

2000 • 80 citations

A Novel Member of the Tob Family of Proteins Controls Sexual Fate in Caenorhabditis elegans Germ Cells

2000 • 77 citations

Control of the Cell Morphology and the S Phase Entry by Mitogen-activated Protein Kinase Kinase

1999 • 30 citations

Sequence and developmental expression ofAmphiTob, an amphioxus homolog of vertebrateTob in thePC3/BTG1/Tob family of tumor suppressor genes

1997 • 22 citations