T‐cell memory and recall responses to respiratory virus infections

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

1999 • 5,659 citations

Mortality Associated With Influenza and Respiratory Syncytial Virus in the United States

2003 • 3,627 citations

Dendritic Cells

2001 • 2,164 citations

Preferential Localization of Effector Memory Cells in Nonlymphoid Tissue

2001 • 1,922 citations

Lineage relationship and protective immunity of memory CD8 T cell subsets

2003 • 1,833 citations

Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

2000 • 1,644 citations

Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

2000 • 1,596 citations

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

1989 • 1,587 citations

α4β7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1

1993 • 1,427 citations

Recognition of pathogen-associated molecular patterns by TLR family

2003 • 1,124 citations

Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

2003 • 1,058 citations

Visualizing the generation of memory CD4 T cells in the whole body

2001 • 1,029 citations

Similarities and differences in CD4+ and CD8+ effector and memory T cell generation

2003 • 865 citations

T CELL MEMORY

1998 • 863 citations

Control of Homeostasis of CD8 ⁺ Memory T Cells by Opposing Cytokines

2000 • 847 citations

Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells

2002 • 783 citations

Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity

2004 • 742 citations

Lymphocyte Trafficking and Regional Immunity

1999 • 686 citations

Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia

1998 • 685 citations

Interleukin 15 Is Required for Proliferative Renewal of Virus-specific Memory CD8 T Cells

2002 • 671 citations

Viral infection switches non-plasmacytoid dendritic cells into high interferon producers

2003 • 582 citations

Specific Migratory Dendritic Cells Rapidly Transport Antigen from the Airways to the Thoracic Lymph Nodes

2000 • 554 citations

Pandemic Threat Posed by Avian Influenza A Viruses

2001 • 532 citations

Chemokines Trigger Immediate β2 Integrin Affinity and Mobility Changes

2000 • 517 citations

CD8+ T cells clear influenza virus by perforin or Fas-dependent processes.

1997 • 493 citations

Involvement of Toll-Like Receptor 4 in Innate Immunity to Respiratory Syncytial Virus

2001 • 492 citations

Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics

2005 • 489 citations

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

2005 • 458 citations

In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific.

1984 • 439 citations

CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein

2001 • 433 citations

Correlates of Immune Protection Induced by Live, Attenuated, Cold‐Adapted, Trivalent, Intranasal Influenza Virus Vaccine

2000 • 408 citations

Activated Antigen-Specific CD8+ T Cells Persist in the Lungs Following Recovery from Respiratory Virus Infections

2001 • 403 citations

Heterosubtypic immunity to influenza type A virus in mice. Effector mechanisms and their longevity.

1994 • 400 citations

Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells.

1991 • 372 citations

Dynamics of Blood-Borne CD8 Memory T Cell Migration In Vivo

2004 • 371 citations

Accelerated Migration of Respiratory Dendritic Cells to the Regional Lymph Nodes Is Limited to the Early Phase of Pulmonary Infection

2003 • 362 citations

Roles of alphabeta and gammadelta T Cell Subsets in Viral Immunity

1992 • 350 citations

Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo

2002 • 345 citations

Bronchial lymphoid tissue. I. Morphologic characteristics.

1973 • 344 citations

Cellular events in the lymph node and lung of mice with influenza. Consequences of depleting CD4+ T cells.

1990 • 340 citations

Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells

2002 • 332 citations

The Role of Macrophages in Particle Translocation from Lungs to Lymph Nodes

1985 • 329 citations

CD4 Effector T Cell Subsets in the Response to Influenza

2002 • 328 citations

Memory CD8+ T Cells Provide Innate Immune Protection against Listeria monocytogenes in the Absence of Cognate Antigen

2003 • 326 citations

Dendritic Cells Maximize the Memory CD8 T Cell Response to Infection

2005 • 320 citations

CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa

2002 • 313 citations

The Collagen Binding α1β1 Integrin VLA-1 Regulates CD8 T Cell-Mediated Immune Protection against Heterologous Influenza Infection

2004 • 300 citations

Measuring the diaspora for virus-specific CD8⁺T cells

2001 • 288 citations

Protection from Respiratory Virus Infections Can Be Mediated by Antigen-Specific Cd4+ T Cells That Persist in the Lungs

2001 • 285 citations

Bystander Activation of CD8+ T Cells Contributes to the Rapid Production of IFN-γ in Response to Bacterial Pathogens

2001 • 284 citations

Activated Primary and Memory CD8 T Cells Migrate to Nonlymphoid Tissues Regardless of Site of Activation or Tissue of Origin

2004 • 282 citations

Differential contributions of central and effector memory T cells to recall responses

2005 • 275 citations

Functional Properties and Lineage Relationship of CD8+ T Cell Subsets Identified by Expression of IL-7 Receptor α and CD62L

2005 • 273 citations

Bone Marrow Is a Preferred Site for Homeostatic Proliferation of Memory CD8 T Cells

2005 • 273 citations

CCL25 mediates the localization of recently activated CD8αβ+ lymphocytes to the small-intestinal mucosa

2002 • 258 citations

Memory CD8+ T cells in heterologous antiviral immunity and immunopathology in the lung

2001 • 257 citations

Resistance to and Recovery from Lethal Influenza Virus Infection in B Lymphocyte–deficient Mice

1997 • 239 citations

On the role of antigen in maintaining cytotoxic T-cell memory.

1996 • 237 citations

Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization.

1996 • 237 citations

Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.

1992 • 237 citations

Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo.

1998 • 234 citations

Structure and function of bronchus-associated lymphoid tissue (BALT).

1989 • 226 citations

Differential Antigen Presentation Regulates the Changing Patterns of CD8+ T Cell Immunodominance in Primary and Secondary Influenza Virus Infections

2003 • 207 citations

Cutting Edge: CCR7+ and CCR7− Memory T Cells Do Not Differ in Immediate Effector Cell Function

2002 • 204 citations

Activation, Differentiation, and Migration of Naive Virus-Specific CD8+ T Cells during Pulmonary Influenza Virus Infection

2004 • 204 citations

Differential T Cell Function and Fate in Lymph Node and Nonlymphoid Tissues

2002 • 197 citations

The epidemiology and clinical impact of pandemic influenza

2003 • 193 citations

Memory T Cell Populations in the Lung Airways Are Maintained by Continual Recruitment

2006 • 181 citations

Lymphocyte Homing to Bronchus-associated Lymphoid Tissue (BALT) Is Mediated by L-selectin/PNAd, α4β1 Integrin/VCAM-1, and LFA-1 Adhesion Pathways

2003 • 179 citations

Naive, Effector, and Memory CD8 T Cells in Protection Against Pulmonary Influenza Virus Infection: Homing Properties Rather Than Initial Frequencies Are Crucial

1999 • 178 citations

Preferential migration of effector CD8+ T cells into the interstitium of the normal lung

2005 • 178 citations

Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung

2005 • 177 citations

Mechanism of Protective Immunity Against Influenza Virus Infection in Mice Without Antibodies

1998 • 173 citations

Effector CD8+ T cells mediate inflammation and airway hyper-responsiveness

2004 • 173 citations

Bronchial lymphoid tissue. II. Functional characterisitics.

1973 • 172 citations

Different roles for rcytotoxic T cells in the control of infections with cytopathic versus noncytopathic viruses

1996 • 171 citations

Nasal Lymphoid Tissue (NALT) as a Mucosal Immune Inductive Site

1997 • 170 citations

Recombinant Rat Surfactant-Associated Protein D Inhibits Human T Lymphocyte Proliferation and IL-2 Production

1998 • 168 citations

Functional Subsets of Memory T Cells Identified by CCR7 Expression

2000 • 148 citations

Antigen-Specific CD8+ T Cells Persist in the Upper Respiratory Tract Following Influenza Virus Infection

2001 • 148 citations

Nonspecific Recruitment of Memory CD8+ T Cells to the Lung Airways During Respiratory Virus Infections

2003 • 143 citations

TL1A Synergizes with IL-12 and IL-18 to Enhance IFN-γ Production in Human T Cells and NK Cells

2004 • 137 citations

Recall Proliferation Potential of Memory CD8+ T Cells and Antiviral Protection

2005 • 134 citations

Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells.

1995 • 130 citations

Complex Memory T-Cell Phenotypes Revealed by Coexpression of CD62L and CCR7

2005 • 128 citations

Cutting Edge: Effector Memory CD8+ T Cells Play a Prominent Role in Recall Responses to Secondary Viral Infection in the Lung

2004 • 127 citations

CD8 memory T cells: cross-reactivity and heterologous immunity

2004 • 125 citations

Cutting Edge: L-Selectin (CD62L) Expression Distinguishes Small Resting Memory CD4+ T Cells That Preferentially Respond to Recall Antigen

2003 • 114 citations

Dynamic Regulation of T Cell Immunity by CD43

2002 • 112 citations

Nasal-Associated Lymphoid Tissue: Phenotypic and Functional Evidence for the Primary Role of Peripheral Node Addressin in Naive Lymphocyte Adhesion to High Endothelial Venules in a Mucosal Site

1999 • 112 citations

Protracted Protection to Plasmodium berghei Malaria Is Linked to Functionally and Phenotypically Heterogeneous Liver Memory CD8+ T Cells

2003 • 110 citations

Long-Term Maintenance of Virus-Specific Effector Memory CD8+ T Cells in the Lung Airways Depends on Proliferation

2002 • 108 citations

Lymphotoxin-α-Deficient Mice Make Delayed, But Effective, T and B Cell Responses to Influenza

2002 • 103 citations

Sequence variation in the influenza A virus nucleoprotein associated with escape from cytotoxic T lymphocytes

2004 • 103 citations

Activation of Virus-Specific CD8+ T Cells by Lipopolysaccharide-Induced IL-12 and IL-18

2004 • 101 citations

Dendritic cells and host resistance to infection

2003 • 98 citations

Cellular Immunity and Memory to Respiratory Virus Infections

2001 • 98 citations

Long-term persistence and reactivation of T cell memory in the lung of mice infected with respiratory syncytial virus

2001 • 95 citations

Cutting Edge: Virus-Specific CD4+ Memory T Cells in Nonlymphoid Tissues Express a Highly Activated Phenotype

2002 • 92 citations

Virus-Specific CD8 T Cells in Peripheral Tissues Are More Resistant to Apoptosis Than Those in Lymphoid Organs

2003 • 82 citations

Cutting Edge: Effector Memory CD8+ T Cells in the Lung Airways Retain the Potential to Mediate Recall Responses

2003 • 80 citations

Bystander suppression of allergic airway inflammation by lung resident memory CD8+ T cells

2004 • 78 citations

LFA-1 is required for retention of effector CD8 T cells in mouse lungs

2003 • 77 citations

A morphologic study of rabbit bronchial lymphoid aggregates and lymphoepithelium.

1976 • 71 citations

Characterization of CC‐chemokine receptor 7 expression on murine T cells in lymphoid tissues

2003 • 67 citations

INFLUENZA

2000 • 59 citations

The development and structure of mouse nasal-associated lymphoid tissue: an immuno- and enzyme-histochemical study.

1993 • 55 citations

The Functional Heterogeneity of Type 1 Effector T Cells in Response to Infection Is Related to the Potential for IFN-γ Production

2005 • 53 citations

Anatomical features of anti-viral immunity in the respiratory tract

2004 • 48 citations

Clearance of Sendai virus by CD8⁺ T cells requires direct targeting to virus‐infected epithelium

1995 • 45 citations

Effector lymphoid tissue and its crucial role in protective immunity

2005 • 43 citations

Development of bronchus associated lymphoid tissue (BALT) in the rat, with special reference to T- and B-cells

1983 • 42 citations

Upper Respiratory Tract Resistance to Influenza Infection Is Not Prevented by the Absence of Either Nasal-Associated Lymphoid Tissue or Cervical Lymph Nodes

2005 • 39 citations

The generation and maintenance of memory T and B cells

1999 • 38 citations

Differential regulation of CD43 glycoforms on CD4⁺ and CD8⁺ T lymphocytes in graft-versus-host disease

1994 • 37 citations

Cutting Edge: Dichotomy of Homing Receptor Dependence by Mucosal Effector B Cells: αE Versus L-Selectin

2001 • 36 citations

Reliable generation and use of MHC class II:γ2aFc multimers for the identification of antigen-specific CD4+ T cells

2002 • 29 citations

Dual personality of memory T cells

2002 • 25 citations

Adherence of adoptively transferred alloreactive Th1 cells in lung: partial dependence on LFA-1 and ICAM-1

2000 • 25 citations

Studies on the immune response and pathogenesis of Sendai virus infection of mice. II. The immunoglobulin class of plasma cells in the bronchial sub-mucosa.

1974 • 25 citations

The relation between T-cell expression of LFA-1 and immunological memory.

1993 • 23 citations

Renewal of Peripheral CD8+ Memory T Cells During Secondary Viral Infection of Antibody-Sufficient Mice

2003 • 15 citations

The impact of splenectomy on antiviral T cell memory in mice

2004 • 9 citations

Effects of alveolar surfactant aggregates on T-lymphocyte proliferation

2001 • 8 citations