Activated Antigen-Specific CD8+ T Cells Persist in the Lungs Following Recovery from Respiratory Virus Infections

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1998 • 1,996 citations

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Immunological Memory and Protective Immunity: Understanding Their Relation

1996 • 1,771 citations

Turnover of naive- and memory-phenotype T cells.

1994 • 900 citations

T CELL MEMORY

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Massive Expansion of Antigen-Specific CD8+ T Cells during an Acute Virus Infection

1998 • 794 citations

Induction and Exhaustion of Lymphocytic Choriomeningitis Virus–specific Cytotoxic T Lymphocytes Visualized Using Soluble Tetrameric Major Histocompatibility Complex Class I–Peptide Complexes

1998 • 733 citations

Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia

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Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.

1985 • 526 citations

IMMUNITY TO INFLUENZA IN MAN

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The biology and medicine of rabbits and rodents

1977 • 406 citations

Heterosubtypic immunity to influenza type A virus in mice. Effector mechanisms and their longevity.

1994 • 400 citations

Differentiation of Naive CTL to Effector and Memory CTL: Correlation of Effector Function with Phenotype and Cell Division

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Quantification of antigen specific CD8+ T cells using an ELISPOT assay

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The Immune Response to Influenza Infection

1986 • 321 citations

Generation of both cross-reactive and virus-specific T-cell populations after immunization with serologically distinct influenza A viruses.

1977 • 285 citations

A Previously Unrecognized H-2D^b-Restricted Peptide Prominent in the Primary Influenza A Virus-Specific CD8⁺T-Cell Response Is Much Less Apparent following Secondary Challenge

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Induction of Partial Specific Heterotypic Immunity in Mice by a Single Infection with Influenza A Virus

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Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.

1992 • 237 citations

Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization.

1996 • 237 citations

Differentiating between Memory and Effector Cd8 T Cells by Altered Expression of Cell Surface O-Glycans

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Outcome of Influenza Infection: Effect of Site of Initial Infection and Heterotypic Immunity

1980 • 164 citations

Heterosubtypic Immunity to Lethal Influenza A Virus Infection Is Associated with Virus-Specific CD8+Cytotoxic T Lymphocyte Responses Induced in Mucosa-Associated Tissues

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Cross-Subtype Protection in Humans During Sequential, Overlapping, and/or Concurrent Epidemics Caused by H3N2 and H1N1 Influenza Viruses

1985 • 143 citations

Induction and Visualization of Mucosal Memory CD8 T Cells Following Systemic Virus Infection

1999 • 143 citations

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without “memory T cells”?

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Temporal loss of the activated L-selectin-low phenotype for virus-specific CD8+ memory T cells.

1995 • 130 citations

Immunological memory

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1992 • 117 citations

Influenza virus RNA in the lung and lymphoid tissue of immunologically intact and CD4-depleted mice

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Therapeutic Effects of Tumor-Reactive Type 1 and Type 2 CD8+ T Cell Subpopulations in Established Pulmonary Metastases

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Long-Term Persistence of Activated Cytotoxic T Lymphocytes after Viral Infection of the Central Nervous System

1998 • 105 citations

Variation of bronchoalveolar lymphocyte phenotypes with age in the physiologically normal human lung

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Cytolytically active memory CTL present in lymphocytic choriomeningitis virus-immune mice after clearance of virus infection.

1997 • 97 citations

The MHC class l-restricted T cell response to Sendai virus infection in C57BL/6 mice: a single immunodominant epitope elicits an extremely diverse repertoire of T cells

1994 • 95 citations

Regulation of T‐cell activation in the lung: alveolar macrophages induce reversible T‐cell anergy in vitro associated with inhibition of interleukin‐2 receptor signal transduction

1996 • 82 citations

The Recovery of Mice from Influenza Virus Infection: Adoptive Transfer of Immunity with Immune T Lymphocytes

1978 • 81 citations

Immunodominance of major histocompatibility complex class I-restricted influenza virus epitopes can be influenced by the T-cell receptor repertoire

1995 • 81 citations

Functionally Heterogeneous CD8⁺T-Cell Memory Is Induced by Sendai Virus Infection of Mice

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Enumeration of Antigen-Presenting Cells in Mice Infected with Sendai Virus

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Host response to Sendai virus in mice lacking class II major histocompatibility complex glycoproteins

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Cytotoxic T Lymphocytes Specific for Influenza Virus

1994 • 61 citations

Purification and characterization of intraparenchymal lung lymphocytes.

1990 • 59 citations

Efficient priming of CD8+ memory T cells specific for a subdominant epitope following Sendai virus infection.

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Individuals Infected with Two Subtypes of Influenza A Virus in the Same Season

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Functionally distinct T cells in three compartments of the respiratory tract after influenza virus infection

1996 • 54 citations

Heterotypic Immune Mice Lose Protection against Influenza Virus Infection with Senescence

1993 • 44 citations

CD4+ T Cell Priming Accelerates the Clearance of Sendai Virus in Mice, but Has a Negative Effect on CD8+ T Cell Memory

2000 • 43 citations

Discussion

1995 • 43 citations

Regulation of T‐cell activation in the lung: isolated lung T cells exhibit surface phenotypic characteristics of recent activation including down‐modulated T‐cell receptors, but are locked into the G₀/G₁ phase of the cell cycle

1996 • 39 citations

The generation and maintenance of memory T and B cells

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A comparison of the expression of lymphocyte activation markers in blood, bronchial biopsies and bronchoalveolar lavage: evidence for an enrichment of activated T lymphocytes in the bronchoalveolar space

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Cross-Protection in Mice After Immunization with H2N2, H3N2, and Heq2Neq2 Influenza Virus Strains

1978 • 10 citations

Effects of cell mediated immunity in influenza virus infection in mice.

1977 • 9 citations