Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

T cell receptor antagonist peptides induce positive selection

1994 • 2,818 citations

Innate immunity: impact on the adaptive immune response

1997 • 1,542 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

MECHANISMS OF MHC CLASS I–RESTRICTED ANTIGEN PROCESSING

1998 • 1,017 citations

DEGRADATION OF CELL PROTEINS AND THE GENERATION OF MHC CLASS I-PRESENTED PEPTIDES

1999 • 898 citations

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

2001 • 861 citations

Viral Subversion of the Immune System

2000 • 833 citations

Vaccinia virus expression vector: coexpression of beta-galactosidase provides visual screening of recombinant virus plaques.

1985 • 789 citations

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4−8+ T cells

1992 • 726 citations

Cellular immune responses to HIV

2001 • 639 citations

Cytotoxic T-cell immunity to virus-infected non-haematopoietic cells requires presentation of exogenous antigen

1999 • 586 citations

Lymph-Borne Chemokines and Other Low Molecular Weight Molecules Reach High Endothelial Venules via Specialized Conduits While a Functional Barrier Limits Access to the Lymphocyte Microenvironments in Lymph Node Cortex

2000 • 562 citations

In Vivo Detection of Dendritic Cell Antigen Presentation to CD4+ T Cells

1997 • 560 citations

In Vivo Activation of Antigen-Specific CD4 T Cells

2001 • 498 citations

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages

1995 • 416 citations

Detection of rare antigen-presenting cells by the lacZ T-cell activation assay suggests an expression cloning strategy for T-cell antigens.

1992 • 407 citations

Inhibition of dendritic cell maturation by herpes simplex virus

1999 • 369 citations

Vaccinia Virus Inhibits the Maturation of Human Dendritic Cells: A Novel Mechanism of Immune Evasion

1999 • 365 citations

Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen.

1988 • 331 citations

Infection of Human Dendritic Cells by Dengue Virus Causes Cell Maturation and Cytokine Production

2001 • 315 citations

Dissecting the Multifactorial Causes of Immunodominance in Class I–Restricted T Cell Responses to Viruses

2000 • 312 citations

Mechanisms of Exogenous Antigen Presentation by MHC Class I Molecules in Vitro and in Vivo: Implications for Generating CD8+ T Cell Responses to Infectious Agents, Tumors, Transplants, and Vaccines

1999 • 293 citations

Immunosuppression and Resultant Viral Persistence by Specific Viral Targeting of Dendritic Cells

2000 • 283 citations

Role of Dendritic Cell Targeting in Venezuelan Equine Encephalitis Virus Pathogenesis

2000 • 261 citations

Intracellular Localization of Proteasomal Degradation of a Viral Antigen

1999 • 214 citations

Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever.

1997 • 209 citations

Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum.

1995 • 163 citations

Temporal regulation of influenza hemagglutinin expression in vaccinia virus recombinants and effects on the immune response

1986 • 149 citations

Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice.

1992 • 149 citations

Antigen expression by dendritic cells correlates with the therapeutic effectiveness of a model recombinant poxvirus tumor vaccine

1997 • 144 citations

Virus-specific antigen presentation by different subsets of cells from lung and mediastinal lymph node tissues of influenza virus-infected mice

1995 • 118 citations

The Distinctive Features of Influenza Virus Infection of Dendritic Cells

1998 • 113 citations

Requirements for Bone Marrow–Derived Antigen-Presenting Cells in Priming Cytotoxic T Cell Responses to Intracellular Pathogens

2000 • 99 citations

Mechanisms of Viral Interference with MHC Class I Antigen Processing and Presentation

1999 • 96 citations

Multiple Antigen-Specific Processing Pathways for Activating Naive CD8+ T Cells In Vivo

2001 • 90 citations

Enumeration of Antigen-Presenting Cells in Mice Infected with Sendai Virus

1999 • 70 citations

Cross-Presentation by Dendritic Cells of Tumor Antigen Expressed in Apoptotic Recombinant Canarypox Virus-Infected Dendritic Cells

2001 • 67 citations

Cutting Edge: Recombinant Adenoviruses Induce CD8 T Cell Responses to an Inserted Protein Whose Expression Is Limited to Nonimmune Cells

2001 • 55 citations

Vaccinia Virus Infection Disarms the Mitochondrion-Mediated Pathway of the Apoptotic Cascade by Modulating the Permeability Transition Pore

2001 • 53 citations