Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung

Phenotypic Analysis of Antigen-Specific T Lymphocytes

1996 • 3,611 citations

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

2004 • 3,455 citations

Respiratory Syncytial Virus Infection in Elderly and High-Risk Adults

2005 • 1,918 citations

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells

2003 • 1,790 citations

Effector and memory T-cell differentiation: implications for vaccine development

2002 • 1,757 citations

Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections

2002 • 1,583 citations

Phenotypic and Functional Separation of Memory and Effector Human CD8+ T Cells

1997 • 1,391 citations

Respiratory Viruses, Symptoms, and Inflammatory Markers in Acute Exacerbations and Stable Chronic Obstructive Pulmonary Disease

2001 • 1,008 citations

Cytokine control of memory T-cell development and survival

2003 • 885 citations

Functional subsets of human helper-inducer cells defined by a new monoclonal antibody, UCHL1.

1986 • 515 citations

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

2004 • 489 citations

Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8 ⁺ memory T cell subsets

2004 • 466 citations

Activated Antigen-Specific CD8+ T Cells Persist in the Lungs Following Recovery from Respiratory Virus Infections

2001 • 403 citations

Emergence of a CD4+CD28− Granzyme B+, Cytomegalovirus-Specific T Cell Subset after Recovery of Primary Cytomegalovirus Infection

2004 • 354 citations

Human CD8+ T-cell differentiation in response to viruses

2003 • 299 citations

Protection from Respiratory Virus Infections Can Be Mediated by Antigen-Specific Cd4+ T Cells That Persist in the Lungs

2001 • 285 citations

Expression of the Murine CD27 Ligand CD70 In Vitro and In Vivo

2003 • 193 citations

Frequencies of Circulating Cytolytic, CD45RA+CD27−, CD8+ T Lymphocytes Depend on Infection with CMV

2003 • 169 citations

IL-7 receptor α chain expression distinguishes functional subsets of virus-specific human CD8+ T cells

2005 • 162 citations

The CD27⁻ subset of peripheral blood memory CD4⁺ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo

1992 • 157 citations

Proliferation Requirements of Cytomegalovirus-Specific, Effector-Type Human CD8+ T Cells

2002 • 149 citations

Nonspecific Recruitment of Memory CD8+ T Cells to the Lung Airways During Respiratory Virus Infections

2003 • 143 citations

The Size and Phenotype of Virus-Specific T Cell Populations Is Determined by Repetitive Antigenic Stimulation and Environmental Cytokines

2004 • 121 citations

CD28 engagement by B7/BB-1 induces transient down-regulation of CD28 synthesis and prolonged unresponsiveness to CD28 signaling.

1993 • 116 citations

Respiratory Syncytial Virus–Specific CD8⁺Memory T Cell Responses in Elderly Persons

2005 • 103 citations

Extraction of immune and inflammatory cells from human lung parenchyma: evaluation of an enzymatic digestion procedure.

1986 • 84 citations

Expression of IL-15 in inflammatory pulmonary diseases

2001 • 84 citations

Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+)

2003 • 69 citations

Expression of tumor necrosis factor-receptor superfamily members by lung T lymphocytes in interstitial lung disease.

1996 • 65 citations

Analysis of the Frequencies and of the Memory T Cell Phenotypes of Human CD8⁺T Cells Specific for Influenza A Viruses

2003 • 64 citations

Antigen‐presenting cell‐derived signals determine expression levels of CD70 on‘qc primed T cells

1997 • 60 citations

Soluble and Cellular Markers of T Cell Activation in Patients with Pulmonary Sarcoidosis

1993 • 59 citations

Limiting-dilution analysis of T cells extracted from solid human lung tissue: comparison of precursor frequencies for proliferative responses and lymphokine production between lung and blood T cells from individual donors.

1988 • 47 citations

Most Human Pulmonary Infiltrating Lymphocytes Display the Surface Immune Phenotype and Functional Responses of Sensitized T Cells

1991 • 36 citations

Interleukin-4 Receptor–Stat6 Signaling in Murine Infections with a Tissue-Dwelling Nematode Parasite

2001 • 32 citations