Enhancer-dependent interaction between 5' and 3' splice sites in trans.

SR proteins: a conserved family of pre-mRNA splicing factors.

1992 • 766 citations

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

1993 • 741 citations

Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

1994 • 622 citations

A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro

1990 • 500 citations

The essential pre-mRNA splicing factor SF2 influences 5′ splice site selection by activating proximal sites

1990 • 454 citations

Intron sequences involved in lariat formation during pre-mRNA splicing

1985 • 402 citations

The role of exon sequences in splice site selection.

1993 • 367 citations

Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells.

1990 • 359 citations

A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA

1993 • 332 citations

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.

1993 • 300 citations

An ATP-independent complex commits pre-mRNA to the mammalian spliceosome assembly pathway.

1991 • 297 citations

General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer.

1993 • 286 citations

Specific commitment of different pre-mRNAs to splicing by single SR proteins

1993 • 272 citations

SR proteins promote the first specific recognition of Pre-mRNA and are present together with the U1 small nuclear ribonucleoprotein particle in a general splicing enhancer complex.

1994 • 267 citations

Mechanisms for selecting 5′ splice sites in mammalian pre-mRNA splicing

1994 • 261 citations

Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro

1991 • 244 citations

General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection.

1992 • 241 citations

U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon.

1992 • 225 citations

Trans splicing of mRNA precursors

1985 • 205 citations

Positive Control of Pre-mRNA Splicing in Vitro

1992 • 199 citations

The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site.

1992 • 198 citations

Pathways for selection of 5′ splice sites by U1 snRNPs and SF2/ASF.

1993 • 192 citations

The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2

1994 • 182 citations

Trans splicing of mrna precursors in vitro

1985 • 180 citations

SR proteins can compensate for the loss of U1 snRNP functions in vitro.

1994 • 160 citations

Complementation by SR Proteins of Pre-mRNA Splicing Reactions Depleted of U1 snRNP

1994 • 152 citations

A splicing enhancer exhibits both constitutive and regulated activities.

1994 • 136 citations

Intrinsic U2AF binding is modulated by exon enhancer signals in parallel with changes in splicing activity.

1995 • 133 citations

Distinct functions of SR proteins in recruitment of U1 small nuclear ribonucleoprotein to alternative 5' splice sites.

1995 • 102 citations

Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps.

1995 • 86 citations

Spliced leader RNAs from lower eukaryotes are trans- spliced in mammalian cells

1992 • 84 citations

Trans-splicing as a possible molecular mechanism for the multiple isotype expression of the immunoglobulin gene.

1991 • 73 citations

Guides to the Heart of the Spliceosome

1993 • 55 citations

Immunoglobulin double-isotype expression by trans-mRNA in a human immunoglobulin transgenic mouse.

1989 • 55 citations

Synthesis and regulation of trans-mRNA encoding the immunoglobulin epsilon heavy chain.

1993 • 29 citations

Intermolecular recombination of the c-myb proto-oncogene coding sequences in chicken: clues for a mechanism.

1990 • 6 citations

Intermolecular recombination of human c-myb proto-oncogene coding sequences.

1991 • 4 citations