Human Keratinocytes Release ATP and Utilize Three Mechanisms for Nucleotide Interconversion at the Cell Surface

Receptors for Purines and Pyrimidines

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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

THE ATP SYNTHASE—A SPLENDID MOLECULAR MACHINE

1997 • 1,934 citations

Purinoceptors: Are there families of P2X and P2Y purinoceptors?

1994 • 1,079 citations

5′-Nucleotidase: molecular structure and functional aspects

1992 • 864 citations

CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP

1995 • 647 citations

International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits.

2001 • 639 citations

Angiostatin binds ATP synthase on the surface of human endothelial cells

1999 • 520 citations

Purinergic signalling: ATP release.

2001 • 505 citations

Ecto-ATPases: Identities and Functions

1995 • 503 citations

Storage and Release of ATP from Astrocytes in Culture

2003 • 489 citations

Ectopic β-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis

2003 • 447 citations

Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family

2003 • 412 citations

The multidrug resistance (mdr1) gene product functions as an ATP channel.

1993 • 372 citations

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

1994 • 354 citations

Ecto‐enzyme and signaling functions of lymphocyte CD 7 3

1998 • 322 citations

Endothelial cell surface F ₁ -F _O ATP synthase is active in ATP synthesis and is inhibited by angiostatin

2001 • 313 citations

Constitutive Release of ATP and Evidence for Major Contribution of Ecto-nucleotide Pyrophosphatase and Nucleoside Diphosphokinase to Extracellular Nucleotide Concentrations

2000 • 313 citations

Direct Demonstration of Mechanically Induced Release of Cellular UTP and Its Implication for Uridine Nucleotide Receptor Activation

1997 • 286 citations

[59] Inhibitors of the ATP synthetase systems

1979 • 256 citations

A release mechanism for stored ATP in ocular ciliary epithelial cells

1998 • 233 citations

Two novel families of ectonucleotidases: molecular structures, catalytic properties and a search for function

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Colocalization of ATP Release Sites and Ecto-ATPase Activity at the Extracellular Surface of Human Astrocytes

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The catalytic mechanism of nucleoside diphosphate kinases.

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Regulation of Ion Channels by ABC Transporters That Secrete ATP

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Extracellular purine metabolism

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Hepatocellular ATP-binding Cassette Protein Expression Enhances ATP Release and Autocrine Regulation of Cell Volume

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Extracellular ATP is a mitogen for 3T3, 3T6, and A431 cells and acts synergistically with other growth factors.

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Possible role of cell surface H+ -ATP synthase in the extracellular ATP synthesis and proliferation of human umbilical vein endothelial cells.

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Purinergic Receptors Are Part of a Functional Signaling System for Proliferation and Differentiation of Human Epidermal Keratinocytes

2003 • 122 citations

Kinetics of the thrombin-induced release of adenosine triphosphate by platelets. Comparison with release of calcium

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Localisation of P2X

1999 • 117 citations

Extracellular ATP formation on vascular endothelial cells is mediated by ecto‐nucleotide kinase activities via phosphotransfer reactions

2001 • 117 citations

Adenosine triphosphate stimulates phosphoinositide metabolism, mobilizes intracellular calcium, and inhibits terminal differentiation of human epidermal keratinocytes.

1992 • 111 citations

Regulation of epidermal homeostasis through P2Y₂receptors

1999 • 109 citations

An Ecto‐Nucleotide Pyrophosphatase Is One of the Main Enzymes Involved in the Extracellular Metabolism of ATP in Rat C6 Glioma

1999 • 105 citations

Domain Closure in Adenylate Kinase

1996 • 99 citations

Cellular ATP release by the cystic fibrosis transmembrane conductance regulator

1996 • 89 citations

Extracellular nucleotides elevate [Ca2+]i in rat osteoblastic cells by interaction with two receptor subtypes

1992 • 86 citations

Release and interconversion of P2 receptor agonists by human osteoblast‐like cells

2003 • 76 citations

Human Keratinocytes Express Multiple P2Y-Receptors: Evidence for Functional P2Y1, P2Y2, and P2Y4 Receptors

2003 • 74 citations

Human Airway Ecto-adenylate Kinase

2003 • 67 citations

Secreted and Cell-Associated Adenylate Kinase and Nucleoside Diphosphokinase Contribute to Extracellular Nucleotide Metabolism on Human Airway Surfaces

2002 • 63 citations

Identification of a novel human adenylate kinase

1999 • 57 citations

Identification of a novel adenylate kinase system in the brain: Cloning of the fourth adenylate kinase

1998 • 56 citations

Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation

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Electrodiffusional ATP movement through CFTR and other ABC transporters

2001 • 39 citations

Adenylate kinases in man: evidence for a third locus

1976 • 36 citations

Receptor activation regulates cortical, but not vesicular localization of NDP kinase

2003 • 26 citations

Characterization of the P2 receptors on the human umbilical vein endothelial cell line ECV304

1998 • 25 citations

Nucleotide Transport Through the Cystic Fibrosis Transmembrane Conductance Regulator

1997 • 21 citations

ADP stimulation of inositol phosphates in hepatocytes: role of conversion to ATP and stimulation of P2Y₂ receptors

2003 • 20 citations

ATP Compartmentation in Neuroendocrine Secretory Vesicles

1990 • 19 citations