Human Keratinocytes Express Multiple P2Y-Receptors: Evidence for Functional P2Y1, P2Y2, and P2Y4 Receptors

Receptors for Purines and Pyrimidines

2012 • 4,065 citations

Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.

1988 • 4,008 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides

1993 • 1,259 citations

Purinoceptors: Are there families of P2X and P2Y purinoceptors?

1994 • 1,079 citations

Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor

1987 • 703 citations

Reversible inhibition of normal human prokeratinocyte proliferation by type beta transforming growth factor-growth inhibitor in serum-free medium.

1986 • 559 citations

Ionic Calcium Reservoirs in Mammalian Epidermis: Ultrastructural Localization by Ion-Capture Cytochemistry

1985 • 440 citations

Fibronectin inhibits the terminal differentiation of human keratinocytes

1989 • 402 citations

Further subclassification of ATP receptors based on agonist studies

1991 • 374 citations

Uridine nucleotide selectivity of three phospholipase C-activating P2 receptors: identification of a UDP-selective, a UTP-selective, and an ATP- and UTP-specific receptor.

1996 • 348 citations

Pharmacology and electrophysiology of ATP-activated ion channels

1992 • 326 citations

The regulation of vascular function by P2 receptors: multiple sites and multiple receptors

1998 • 274 citations

Chapter 15 Serial Cultivation of Normal Human Epidermal Keratinocytes

1980 • 266 citations

P2 receptor subtypes in the cardiovascular system

1998 • 253 citations

Structure, function, and differentiation of the keratinocyte

1989 • 238 citations

G protein-coupled P2 purinoceptors: from molecular biology to functional responses

1995 • 187 citations

Regulation of Ion Channels by ABC Transporters That Secrete ATP

1995 • 174 citations

Extracellular purine metabolism

1996 • 167 citations

Density-dependent modulation of synthesis of keratins 1 and 10 in the human keratinocyte line HACAT and in ras-transfected tumorigenic clones

1989 • 164 citations

Agonist Action of Adenosine Triphosphates at the Human P2Y₁Receptor

1998 • 162 citations

Extracellular ATP is a mitogen for 3T3, 3T6, and A431 cells and acts synergistically with other growth factors.

1989 • 149 citations

Numbering of cloned P2 purinoceptors

1996 • 148 citations

Modulation of astroglial cell proliferation by analogues of adenosine and ATP in primary cultures of rat striatum

1994 • 143 citations

Extracellular ATP and ADP stimulate proliferation of porcine aortic smooth muscle cells

1992 • 140 citations

An increase in intracellular free calcium is an early event during differentiation of cultured human keratinocytes

1989 • 114 citations

Adenosine triphosphate stimulates phosphoinositide metabolism, mobilizes intracellular calcium, and inhibits terminal differentiation of human epidermal keratinocytes.

1992 • 111 citations

Regulation of epidermal homeostasis through P2Y₂receptors

1999 • 109 citations

Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+

1993 • 102 citations

Propagation of Mechanically Induced Intercellular Calcium Waves via Gap Junctions and ATP Receptors in Rat Liver Epithelial Cells

1997 • 99 citations

Extracellular ATP shows synergistic enhancement of DNA synthesis when combined with agents that are active in wound healing or as neurotransmitters

1990 • 95 citations

Extracellular nucleotides stimulate proliferation in MCF-7 breast cancer cells via P2-purinoceptors

1997 • 88 citations

Extracellular nucleotides elevate [Ca2+]i in rat osteoblastic cells by interaction with two receptor subtypes

1992 • 86 citations

Cloning of P2Y6 cDNAs and Identification of a Pseudogene: Comparison of P2Y Receptor Subtype Expression in Bone and Brain Tissues

1997 • 77 citations

Intracellular calcium oscillations induced by ATP in airway epithelial cells

1999 • 70 citations

Down-Regulation of P_2U-Purinergic Nucleotide Receptor Messenger RNA Expression DuringIn VitroDifferentiation of Human Myeloid Leukocytes by Phorbol Esters or Inflammatory Activators

1997 • 59 citations

Ca2+ entry modulates oscillation frequency by triggering Ca2+ release

1996 • 46 citations

Expression and function of connexin in normal and transformed human keratinocytes in culture

1994 • 46 citations

Expanding field of purinergic signaling

2001 • 39 citations

Growth and differentiation stimuli induce different and distinct increases in intracellular free calcium in human keratinocytes

1993 • 35 citations

Intracellular calcium as a second messenger following growth stimulation of human keratinocytes

2010 • 33 citations

Intracellular free calcium and growth changes in single human keratinocytes in response to vitamin D and five 20-epi-analogues

1994 • 26 citations

Phospholipase C-Mediated Signaling Is Altered During HaCaT Cell Proliferation and Differentiation

1997 • 18 citations