NF-κB activation and interleukin 6 production in fibroblasts by estrogen receptor-negative breast cancer cell-derived interleukin 1α

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

Structure, Regulation and Function of NF-kappaB

1994 • 2,110 citations

Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death

1996 • 1,962 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Cytokine signal transduction

1994 • 1,358 citations

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

1995 • 1,296 citations

Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity

1995 • 1,287 citations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

1990 • 1,140 citations

Constitutive Activation of NF-κB during Progression of Breast Cancer to Hormone-Independent Growth

1997 • 824 citations

Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis

1996 • 730 citations

Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer.

1997 • 717 citations

Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.

1993 • 704 citations

Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.

1993 • 639 citations

Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice.

1990 • 617 citations

Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines

1992 • 530 citations

NF-κB Activation: The IκB Kinase Revealed?

1997 • 492 citations

I kappa B epsilon, a novel member of the Ikappa B family, controls RelA and cRel NF-kappa B activity

1997 • 394 citations

Impact of the cyclin–dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents

1996 • 328 citations

Immunohistochemical distribution of type IV collagenase in normal, benign, and malignant breast tissue.

1990 • 323 citations

Changes in estrogen receptor, progesterone receptor, and pS2 expression in tamoxifen-resistant human breast cancer.

1995 • 297 citations

Induction of Hepatocyte Growth Factor in Fibroblasts by Tumor-derived Factors Affects Invasive Growth of Tumor Cells : In Vitro Analysis of Tumor-Stromal Interactions

1998 • 291 citations

Differentiation state and invasiveness of human breast cancer cell lines

1994 • 260 citations

Clodronate decreases the frequency of skeletal metastases in women with breast cancer

1996 • 226 citations

Augmentation of type IV collagenase, laminin receptor, and Ki67 proliferation antigen associated with human colon, gastric, and breast carcinoma progression.

1991 • 207 citations

Structural Analysis and Promoter Characterization of the Human Collagenase-3 Gene (MMP13)

1997 • 198 citations

A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene.

1992 • 171 citations

Essential AP-1 and PEA3 binding elements in the human urokinase enhancer display cell type-specific activity.

1991 • 168 citations

TNF initiates E-selectin transcription in human endothelial cells through parallel TRAF-NF-kappa B and TRAF-RAC/CDC42-JNK-c-Jun/ATF2 pathways.

1997 • 150 citations

Regulation of collagenase-3 expression in human breast carcinomas is mediated by stromal-epithelial cell interactions.

1997 • 137 citations

Malignant breast epithelium selects for insulin-like growth factor II expression in breast stroma: evidence for paracrine function.

1995 • 134 citations

Leukemia-inhibitory factor stimulates breast, kidney and prostate cancer cell proliferation by paracrine and autocrine pathways

1996 • 89 citations

IL-4-induced expression of the IL-1 receptor antagonist gene is mediated by STAT6.

1996 • 88 citations

Progression of MCF-7 breast cancer cells to antiestrogen-resistant phenotype is accompanied by elevated levels of AP-1 DNA-binding activity.

1996 • 87 citations

Structural organization and the transcription initiation site of the human hepatocyte growth factor gene

1991 • 84 citations

Urokinase plasminogen activator as a prognostic marker in different subgroups of patients with breast cancer

1994 • 70 citations

The process of malignant progression in human breast cancer

1990 • 67 citations

Vascular expression of E-selectin is increased in estrogen-receptor-negative breast cancer: a role for tumor-cell-secreted interleukin-1 alpha.

1997 • 64 citations

Expression of and response to interleukin 6 (IL6) in human mammary tumors.

1996 • 60 citations

Coordinate enhancement of gelatinase a mRNA and activity levels in human fibroblasts in response to breast‐adenocarcinoma cells

1994 • 58 citations

Distinct conformations of p53 are observed at different stages of keratinocyte differentiation.

1994 • 53 citations

Histologic characteristics of breast cancers with occult lymph node metastases detected by keratin 19 mRNA reverse transcriptase-polymerase chain reaction

1996 • 42 citations

Soluble factor in normal tissues that stimulates high-molecular-weight sialoglycoprotein production by human colon carcinoma cells.

1990 • 40 citations

The potential role of the heparin-binding growth factor pleiotrophin in breast cancer

1994 • 39 citations

Gene therapy through signal transduction pathways and angiogenic growth factors as therapeutic targets in breast cancer

1994 • 38 citations

Cytokine suppression of protease activation in wild-type p53-dependent and p53-independent apoptosis

1997 • 33 citations

How do breast cancers become hormone resistant?

1994 • 32 citations

Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells

1996 • 31 citations

Involvement of nuclear factor-kappa B in induction of the interleukin-6 gene by leukemia inhibitory factor

1992 • 30 citations

Progression of hormone-dependent adenocarcinoma cells to hormone-independent spindle carcinoma cells in vitro in a clonal spontaneous rat mammary tumor cell line.

1995 • 19 citations

Differential Effect of Nonidet P40 on DNA Binding of Transcription Factors

1997 • 9 citations