A novel complex between the p65 subunit of NF-kappa B and c-Rel binds to a DNA element involved in the phorbol ester induction of the human urokinase gene.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.

1990 • 1,377 citations

Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity.

1991 • 1,300 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

The inducible transcription activator NF-κB: regulation by distinct protein subunits

1991 • 1,079 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen

1987 • 969 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

The p65 subunit is responsible for the strong transcription activating potential of NF-kappa B.

1991 • 805 citations

Human growth hormone as a reporter gene in regulation studies employing transient gene expression.

1986 • 667 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide

1991 • 604 citations

Plasminogen activator in early embryogenesis: Enzyme production by trophoblast and parietal endoderm

1976 • 590 citations

Cloning and expression of AP-2, a cell-type-specific transcription factor that activates inducible enhancer elements.

1988 • 578 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

Characterization of the activation of latent TGF-beta by co-cultures of endothelial cells and pericytes or smooth muscle cells: a self-regulating system.

1990 • 449 citations

Isolation of a rel -related Human cDNAThat Potentially Encodes the 65-kD Subunit of NF-κB

1991 • 448 citations

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

1990 • 445 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

Activation of Interleukin-6 Gene Expression through the NF-κB Transcription Factor

1990 • 379 citations

DNA binding of purified transcription factor NF-kappa B. Affinity, specificity, Zn2+ dependence, and differential half-site recognition.

1991 • 349 citations

The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function

1990 • 325 citations

Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter.

1988 • 308 citations

Plasminogen activators in tissue remodeling and invasion: mRNA localization in mouse ovaries and implanting embryos.

1989 • 287 citations

NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit.

1991 • 287 citations

TNF stimulates expression of mouse MHC class I genes by inducing an NF kappa B-like enhancer binding activity which displaces constitutive factors.

1989 • 275 citations

NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells.

1990 • 260 citations

Human Growth Hormone as a Reporter Gene in Regulation Studies Employing Transient Gene Expression

1986 • 223 citations

A family of constitutive C/EBP-like DNA binding proteins attenuate the IL-1 alpha induced, NF kappa B mediated trans-activation of the angiotensinogen gene acute-phase response element.

1990 • 180 citations

A human rel proto-oncogene cDNA containing an Alu fragment as a potential coding exon.

1989 • 171 citations

The 65-kD subunit of NF-kappa B is a receptor for I kappa B and a modulator of DNA-binding specificity.

1990 • 167 citations

The mouse c-rel protein has an N-terminal regulatory domain and a C-terminal transcriptional transactivation domain.

1990 • 164 citations

c-rel activates but v-rel suppresses transcription from kappa B sites.

1991 • 146 citations

A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglobulin genes.

1990 • 144 citations

Transcription factor PEA3 participates in the induction of urokinase plasminogen activator transcription in murine keratinocytes stimulated with epidermal growth factor or phorbol-ester

1990 • 143 citations

Different localization of the product of the v-rel oncogene in chicken fibroblasts and spleen cells correlates with transformation by REV-T

1986 • 142 citations

Inhibition of transcription factors belonging to the rel/NF-kappa B family by a transdominant negative mutant.

1991 • 138 citations

An upstream enhancer and a negative element in the 5' flanking region of the human urokinase plasminogen activator gene

1988 • 112 citations

Urokinase-dependent cell surface proteolysis and cancer.

1990 • 85 citations

Putative Metal Finger Structure of the Human Immunodeficiency Virus Type 1 Enhancer Binding Protein HIV-EP1

1989 • 79 citations

Use of antipeptide antibodies to demonstrate external orientation of the NH2-terminus of the low density lipoprotein receptor in the plasma membrane of fibroblasts.

1983 • 77 citations

The urokinase receptor and regulation of cell surface plasminogen activation

1990 • 75 citations

Angiotensinogen gene-inducible enhancer-binding protein 1, a member of a new family of large nuclear proteins that recognize nuclear factor kappa B-binding sites through a zinc finger motif.

1991 • 62 citations

The SV40 TC-II(kappa B) enhanson binds ubiquitous and cell type specifically inducible nuclear proteins from lymphoid and non-lymphoid cell lines.

1989 • 61 citations

A Large Protein Containing Zinc Finger Domains Binds to Related Sequence Elements in the Enhancers of the Class I Major Histocompatibility Complex and Kappa Immunoglobulin Genes

1990 • 52 citations

The Mouse c-rel Protein Has an N-Terminal Regulatory Domain and a C-Terminal Transcriptional Transactivation Domain

1990 • 50 citations

The v-rel and c-rel proteins exist in high molecular weight complexes in avian and murine cells.

1991 • 37 citations

Angiotensinogen Gene-Inducible Enhancer-Binding Protein 1, a Member of a New Family of Large Nuclear Proteins That Recognize Nuclear Factor KB-Binding Sites through a Zinc Finger Motif

1991 • 22 citations