Immunization of Malignant Melanoma Patients with Full-Length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod as Vaccine Adjuvant
Data up to Jan 2025
Total Citations Per Year
Abstract
References (53)
AJCC Cancer Staging Manual
2016 • 16,972 citations
Pathogen Recognition and Innate Immunity
2006 • 11,197 citations
Toxicity and response criteria of the Eastern Cooperative Oncology Group
1982 • 10,605 citations
AJCC Cancer Staging Manual
2002 • 6,356 citations
Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8
2004 • 3,766 citations
Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
2004 • 3,325 citations
Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway
2002 • 2,438 citations
AJCC Cancer Staging Manual. 6th ed
2002 • 2,374 citations
Recognition of single-stranded RNA viruses by Toll-like receptor 7
2004 • 1,777 citations
Cancer/testis antigens, gametogenesis and cancer
2005 • 1,541 citations
Interferons, immunity and cancer immunoediting
2006 • 1,497 citations
Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets
2002 • 461 citations
Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans
2004 • 446 citations
Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod
2002 • 378 citations
Imiquimod and the imidazoquinolones: mechanism of action and therapeutic potential
2002 • 374 citations
Triggering TLR signaling in vaccination
2005 • 359 citations
NY‐ESO‐1: Review of an Immunogenic Tumor Antigen
2006 • 354 citations
Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity
2006 • 352 citations
Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells
2007 • 351 citations
Toll-like receptors and dendritic cells: for whom the bug tolls
2004 • 334 citations
HIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+T cell responses in nonhuman primates
2005 • 329 citations
Treatment of genital warts with an immune-response modifier (imiquimod)
1998 • 308 citations
Imiquimod, a Topical Immune Response Modifier, Induces Migration of Langerhans Cells11The authors have declared a conflict of interest.
2000 • 295 citations
Toll-Like Receptor Ligands Modulate Dendritic Cells to Augment Cytomegalovirus- and HIV-1-Specific T Cell Responses
2003 • 292 citations
Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming
2007 • 290 citations
Imiquimod 5% cream for the treatment of actinic keratosis: results from two phase III, randomized, double-blind, parallel group, vehicle-controlled trials
2004 • 288 citations
Toll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primates
2006 • 279 citations
Nucleic acid agonists for Toll‐like receptor 7 are defined by the presence of uridine ribonucleotides
2006 • 273 citations
A Randomized, Controlled, Molecular Study of Condylomata Acuminata Clearance during Treatment with Imiquimod
1998 • 255 citations
Human Langerhans Cells Express a Specific TLR Profile and Differentially Respond to Viruses and Gram-Positive Bacteria
2006 • 250 citations
Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from a randomized vehicle-controlled phase III study in Europe
2005 • 235 citations
Tumor Antigen Expression in Melanoma Varies According to Antigen and Stage
2006 • 229 citations
Toll-like receptors and acquired immunity
2004 • 207 citations
Identification and Characterization of pDC-Like Cells in Normal Mouse Skin and Melanomas Treated with Imiquimod
2004 • 205 citations
The TLR-7 Agonist, Imiquimod, Enhances Dendritic Cell Survival and Promotes Tumor Antigen-Specific T Cell Priming: Relation to Central Nervous System Antitumor Immunity
2006 • 205 citations
Innate immunity — cross-talk with adaptive immunity through pattern recognition receptors and cytokines
2006 • 197 citations
Vaccine-Induced CD4+ T Cell Responses to MAGE-3 Protein in Lung Cancer Patients
2004 • 182 citations
Disease-Independent Skin Recruitment and Activation of Plasmacytoid Predendritic Cells Following Imiquimod Treatment
2005 • 176 citations
Injection of Immature Dendritic Cells into Adjuvant-Treated Skin Obviates the Need for Ex Vivo Maturation
2003 • 168 citations
Phase 1/2 study of subcutaneous and intradermal immunization with a recombinant MAGE-3 protein in patients with detectable metastatic melanoma
2005 • 155 citations
Cutting Edge: Priming of CTL by Transcutaneous Peptide Immunization with Imiquimod
2005 • 154 citations
Booster vaccination of cancer patients with MAGE-A3 protein reveals long-term immunological memory or tolerance depending on priming
2008 • 153 citations
The impact of imiquimod, a Toll-like receptor-7 ligand (TLR7L), on the immunogenicity of melanoma peptide vaccination with adjuvant Flt3 ligand.
2004 • 122 citations
Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors.
2007 • 113 citations
Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery
2004 • 106 citations
The TLR7 Agonist Imiquimod Enhances the Anti-Melanoma Effects of a Recombinant Listeria monocytogenes Vaccine
2005 • 84 citations
Randomized, Single-Blind, Placebo-Controlled Studyof Topical Application of the Immune Response ModulatorResiquimod in HealthyAdults
2003 • 72 citations
Topical delivery of imiquimod to a mouse model as a novel adjuvant for human immunodeficiency virus (HIV) DNA
2004 • 66 citations
NY‐ESO‐1/LAGE‐1 coexpression with MAGE‐A cancer/testis antigens: A tissue microarray study
2005 • 62 citations
Topical imiquimod is a potent adjuvant to a weakly-immunogenic protein prototype vaccine
2005 • 58 citations
Imiquimod and S-27609 as adjuvants of DNA vaccination in a transgenic murine model of HER2/neu-positive mammary carcinoma
2005 • 32 citations
Prolonged Imiquimod Treatment and Graft-versus-Host Reaction: Histological Mimicry in the Skin Infiltration Pattern of the Monocyte-Macrophage-Dendrocyte Lineage
2003 • 14 citations
A phenotype based approach for the immune monitoring of NY-ESO-1-specific CD4+ T cell responses in cancer patients
2005 • 10 citations
Cited By (0)
No citing papers found in database