Two GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeast.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Transformation of intact yeast cells treated with alkali cations

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Mechanisms of intracellular protein transport

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Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

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Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

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A ras-like protein is required for a post-Golgi event in yeast secretion

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Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants.

1992 • 832 citations

Order of events in the yeast secretory pathway

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Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

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The ras protein family: evolutionary tree and role of conserved amino acids

1991 • 573 citations

Chapter 19 Fluorescence Microscopy Methods for Yeast

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A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles

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The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.

1992 • 429 citations

GTPases: Multifunctional Molecular Switches Regulating Vesicular Traffic

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Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport.

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A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

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Rab1b regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments.

1991 • 391 citations

Rab GTPases in vesicular transport

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1991 • 350 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

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Reconstitution of SEC gene product-dependent intercompartmental protein transport

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Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles.

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Homologs of the synaptobrevin/VAMP family of synaptic vesicle proteins function on the late secretory pathway in S. cerevisiae

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Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease

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SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.

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Compartmentalized assembly of oligosaccharides on exported glycoproteins in yeast

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The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

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Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant.

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Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy.

1992 • 278 citations

Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae.

1991 • 268 citations

The GTPase Ypt7p of Saccharomyces cerevisiae is required on both partner vacuoles for the homotypic fusion step of vacuole inheritance.

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Functional compartments of the yeast Golgi apparatus are defined by the sec7 mutation.

1989 • 249 citations

A MOLECULAR DESCRIPTION OF SYNAPTIC VESICLE MEMBRANE TRAFFICKING

1994 • 248 citations

Localization of components involved in protein transport and processing through the yeast Golgi apparatus.

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Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Endocytosis in yeast: Evidence for the involvement of a small GTP-binding protein (Ypt7p)

1992 • 235 citations

The GTP-binding protein Ypt1 is required for transport in vitro: the Golgi apparatus is defective in ypt1 mutants.

1989 • 234 citations

A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments.

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Role of three rab5-like GTPases, Ypt51p, Ypt52p, and Ypt53p, in the endocytic and vacuolar protein sorting pathways of yeast.

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SNARE-Mediated Retrograde Traffic from the Golgi Complex to the Endoplasmic Reticulum

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Osmium ferricyanide fixation improves microfilament preservation and membrane visualization in a variety of animal cell types

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The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transport.

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VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins.

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Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4

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A SNARE-like protein required for traffic through the Golgi complex

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The ras-related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.

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Isolation and characterization of conditional-lethal mutations in the TUB1 alpha-tubulin gene of the yeast Saccharomyces cerevisiae.

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Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4

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Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae.

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[13] Reconstitution of transport from endoplasmic reticulum to golgi complex using endoplasmic reticulum-enriched membrane fraction from yeast

1992 • 97 citations

Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily

1991 • 97 citations

Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity.

1991 • 91 citations

Yeast ypt51p and mammalian rab5: Counterparts with similar function in the early endocytic pathway

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Identification of ras-related, YPT family genes in Schizosaccharomyces pombe.

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Structural and functional analysis of ypt2, an essential ras-related gene in the fission yeast Schizosaccharomyces pombe encoding a Sec4 protein homologue.

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Primary Structure and Product Characterization of the Saccharomyces cerevisiae CHO1 Gene That Encodes Phosphatidylserine Synthase1

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Modulation of the Golgi apparatus in Saccharomyces cerevisiae sec7 mutants as seen by three‐dimensional electron microscopy

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A strategy for the generation of conditional mutations by protein destabilization.

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The ryh1 gene in the fission yeast Schizosaccharomyces pombe encoding a GTP-binding protein related to ras, rho and ypt: structure, expression and identification of its human homologue.

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The Yeast SLY Gene Products, Suppressors of Defects in the Essential GTP-Binding Ypt1 Protein, May Act in Endoplasmic Reticulum-to-Golgi Transport

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The structural genes of internal invertases in Saccharomyces cerevisiae

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Functionality and specific membrane localization of transport GTPases carrying C-terminal membrane anchors of synaptobrevin-like proteins.

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[31] Pulse labeling of yeast cells and spheroplasts

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[35] Ypt proteins in yeast

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Increased efficiency of the Taq polymerase catalyzed polymerase chain reaction

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[61] Computer reconstruction of mitochondria from yeast

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Ultrastructure ofSaccharomyces cerevisiae cells accumulating Golgi organelles

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<scp>V</scp>. Yeast sequencing reports. Identification of a gene encoding a new Ypt/Rab‐like monomeric G‐protein in Saccharomyces cerevisiae

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