Yeast syntaxins Sso1p and Sso2p belong to a family of related membrane proteins that function in vesicular transport.

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Methods in Yeast Genetics

1988 • 4,905 citations

Construction of Phylogenetic Trees

1967 • 3,637 citations

Intracellular Aspects of the Process of Protein Synthesis

1975 • 3,560 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway

1980 • 1,808 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases.

1988 • 977 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations.

1989 • 819 citations

Order of events in the yeast secretory pathway

1981 • 804 citations

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase

1987 • 703 citations

The molecular machinery for secretion is conserved from yeast to neurons.

1993 • 658 citations

Behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae

1975 • 617 citations

SNAPs, a family of NSF attachment proteins involved in intracellular membrane fusion in animals and yeast

1990 • 578 citations

VAMP-1: a synaptic vesicle-associated integral membrane protein.

1988 • 574 citations

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

1989 • 570 citations

VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles.

1992 • 544 citations

Secretion and cell-surface growth are blocked in a temperature-sensitive mutant of Saccharomyces cerevisiae

1979 • 518 citations

Synaptobrevin: an integral membrane protein of 18,000 daltons present in small synaptic vesicles of rat brain.

1989 • 513 citations

VESICLE-MEDIATED PROTEIN SORTING

1992 • 472 citations

PROTEINASE MUTANTS OF SACCHAROMYCES CEREVISIAE

1977 • 460 citations

[76] β-d-Fructofuranoside fructohydrolase from yeast

1975 • 455 citations

Protein sorting in yeast: Mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway

1986 • 429 citations

Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant.

1991 • 415 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

Protein Sorting in Saccharomyces cerevisiae: Isolation of Mutants Defective in the Delivery and Processing of Multiple Vacuolar Hydrolases

1988 • 339 citations

[11] Expression of genes in yeast using the ADCI promoter

1983 • 329 citations

Distinct biochemical requirements for the budding, targeting, and fusion of ER-derived transport vesicles.

1991 • 318 citations

A class of membrane proteins with a C-terminal anchor

1993 • 311 citations

Structure and function of the yeast URA3 gene: expression in Escherichia coli

1984 • 311 citations

SED5 encodes a 39-kD integral membrane protein required for vesicular transport between the ER and the Golgi complex.

1992 • 311 citations

Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1.

1992 • 276 citations

Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae.

1989 • 258 citations

Epimorphin: A mesenchymal protein essential for epithelial morphogenesis

1992 • 222 citations

Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product.

1988 • 220 citations

Protein phosphatase 2A in Saccharomyces cerevisiae: effects on cell growth and bud morphogenesis.

1991 • 210 citations

Assay of vacuolar pH in yeast and identification of acidification-defective mutants.

1989 • 179 citations

BET1, BOS1, and SEC22 Are Members of a Group of Interacting Yeast Genes Required for Transport from the Endoplasmic Reticulum to the Golgi Complex

1990 • 176 citations

The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein.

1992 • 159 citations

The Sec15 protein responds to the function of the GTP binding protein, Sec4, to control vesicular traffic in yeast.

1989 • 144 citations

SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.

1992 • 133 citations

Positively charged residues are important determinants of membrane protein topology

1990 • 132 citations

The SLP1 gene of Saccharomyces cerevisiae is essential for vacuolar morphogenesis and function.

1990 • 123 citations

Primary structure of the multifunctional alpha subunit protein of yeast fatty acid synthase derived from FAS2 gene sequence.

1988 • 121 citations

Sec8p and Sec15p are components of a plasma membrane-associated 19.5S particle that may function downstream of Sec4p to control exocytosis.

1992 • 114 citations

Yeast galactose permease is related to yeast and mammalian glucose transporters

1989 • 106 citations

The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast.

1991 • 97 citations

Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily

1991 • 97 citations

Sec2 protein contains a coiled-coil domain essential for vesicular transport and a dispensable carboxy terminal domain.

1990 • 80 citations

Characterization of a Component of the Yeast Secretion Machinery: Identification of the SEC18 Gene Product

1988 • 79 citations

Bos1p, a membrane protein required for ER to Golgi transport in yeast, co-purifies with the carrier vesicles and with Bet1p and the ER membrane.

1992 • 79 citations

Cloning and sequencing of the yeast Saccharomyces cerevisiae SEC1 gene localized on chromosome IV

1991 • 76 citations

Isolation and characterization of PEP3, a gene required for vacuolar biogenesis in Saccharomyces cerevisiae.

1991 • 71 citations

Neuron-specific antigen HPC-1 from bovine brain reveals strong homology to epimorphin, an essential factor involved in epithelial morphogenesis: Identification of a novel protein family

1992 • 43 citations

Is epimorphin involved in vesicular transport?

1993 • 37 citations

Efficient secretion of Bacillus amyloliquefaciens α-amylase cells by its own signal peptide from Saccharomyces cerevisiae host

1987 • 35 citations

Optimization of Bacillus α‐amylase production by Saccharomyces cerevisiae

1991 • 32 citations

SEC6 encodes an 85 kDa soluble protein required for exocytosis in yeast

1992 • 32 citations

The SLP1 Gene of Saccharomyces cerevisiae Is Essential for Vacuolar Morphogenesis and Function

1990 • 29 citations

Isolation and Characterization of PEP3, a Gene Required for Vacuolar Biogenesis in Saccharomyces cerevisiae

1991 • 21 citations