A strategy for the generation of conditional mutations by protein destabilization.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

Universality and Structure of the N-end Rule

1989 • 472 citations

The degradation signal in a short-lived protein

1989 • 427 citations

The recognition component of the N-end rule pathway.

1990 • 388 citations

Purification of a RAS-Responsive Adenylyl Cyclase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method

1988 • 328 citations

Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast.

1989 • 325 citations

Cotranslational processing and protein turnover in eukaryotic cells

1988 • 201 citations

Notes: Point Mutations in the Yeast Histone H4 Gene Prevent Silencing of the Silent Mating Type Locus HML

1990 • 168 citations

The Yeast ARD1 Gene Product is Required for Repression of Cryptic Mating-Type Information at the HML Locus

1987 • 96 citations

GENETIC APPROACHES TO THE ANALYSIS OF MICROBIAL DEVELOPMENT

1982 • 88 citations

Chapter 12 Induction, Selection, and Experimental Uses of Temperature-Sensitive and Other Conditional Mutants of Yeast

1975 • 37 citations