The ras-related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

ras GENES

1987 • 3,818 citations

Transformation of yeast.

1978 • 2,267 citations

Atlas of Protein Sequence and Structure, 1966.

1967 • 1,463 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

1987 • 1,153 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA

1982 • 764 citations

Comparative biochemical properties of normal and activated human ras p21 protein

1984 • 713 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

1984 • 607 citations

Inhibition of restriction endonuclease Nel I cleavage by phosphorothioate groups and its application to oligonucleotide-directed mutagenesis

1986 • 560 citations

Guanosine Triphosphatase Activating Protein (GAP) Interacts with the p21 ras Effector Binding Domain

1988 • 533 citations

Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H- ras P21

1988 • 532 citations

Genes in S. cerevisiae encoding proteins with domains homologous to the mammalian ras proteins

1984 • 471 citations

The human oestrogen receptor functions in yeast

1988 • 402 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts

1983 • 396 citations

A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

1983 • 396 citations

ras-Related gene sequences identified and isolated from Saccharomyces cerevisiae

1983 • 345 citations

Point mutations identify the conserved, intron-contained TACTAAC box as an essential splicing signal sequence in yeast

1984 • 339 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

Mammalian Glucocorticoid Receptor Derivatives Enhance Transcription in Yeast

1988 • 315 citations

Identification of effector residues and a neutralizing epitope of Ha-ras-encoded p21.

1986 • 291 citations

The ras-related YPT1 gene product in yeast: A GTP-binding protein that might be involved in microtubule organization

1986 • 281 citations

Nucleotide Sequence of the Oncogene Encoding the p21 Transforming Protein of Kirsten Murine Sarcoma Virus

1982 • 256 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Mammalian and Yeast ras Gene Products: Biological Function in Their Heterologous Systems

1985 • 209 citations

Ha-ras proteins exhibit GTPase activity: point mutations that activate Ha-ras gene products result in decreased GTPase activity.

1985 • 195 citations

The JUN oncoprotein, a vertebrate transcription factor, activates transcription in yeast

1988 • 180 citations

Site-directed mutagenesis of cytochrome c shows that an invariant Phe is not essential for function

1985 • 151 citations

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

1987 • 142 citations

A carboxyl-terminal cysteine residue is required for palmitic acid binding and biological activity of the ras-related yeast YPT1 protein.

1988 • 138 citations

The ras-like yeast YPT1 gene is itself essential for growth, sporulation, and starvation response.

1987 • 110 citations

Biochemical properties of the ras-related YPT protein in yeast: a mutational analysis.

1987 • 92 citations

Heterologous expression and characterization of the human R-ras gene product.

1987 • 73 citations

Characterization of functional domains of p21 ras by use of chimeric genes.

1985 • 60 citations

The Ras-Like Yeast Ypt1 Gene is Itself Essential for Growth, Sporulation, and Starvation Response

1987 • 45 citations

Chimeric proteins define variable and essential regions of Ha-ras-encoded protein.

1988 • 31 citations