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A ras-like protein is required for a post-Golgi event in yeast secretion

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Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants.

1992 • 832 citations

Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway

1990 • 721 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

The small GTP-binding protein rab4 controls an early sorting event on the endocytic pathway

1992 • 648 citations

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Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

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1991 • 573 citations

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1988 • 533 citations

Chapter 19 Fluorescence Microscopy Methods for Yeast

1989 • 528 citations

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1988 • 409 citations

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1987 • 403 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

1989 • 387 citations

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1988 • 339 citations

Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase.

1989 • 330 citations

Disruption of genes encoding subunits of yeast vacuolar H(+)-ATPase causes conditional lethality.

1990 • 320 citations

[11] DNA of Saccharomyces cerevisiae

1991 • 308 citations

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae.

1991 • 292 citations

The small GTP-binding protein rab4 is associated with early endosomes.

1991 • 286 citations

Rab proteins and the road maps for intracellular transport

1993 • 276 citations

The amino terminus of the yeast F1-ATPase beta-subunit precursor functions as a mitochondrial import signal.

1986 • 258 citations

Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae.

1989 • 258 citations

Study of a temperature-sensitive mutant of the ras-related YPT1 gene product in yeast suggests a role in the regulation of intracellular calcium

1988 • 243 citations

Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors

1993 • 239 citations

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1992 • 235 citations

Multiple methods of visualizing the yeast vacuole permit evaluation of its morphology and inheritance during the cell cycle.

1987 • 224 citations

[48] Yeast endocytosis assays

1991 • 203 citations

The yeast SLY gene products, suppressors of defects in the essential GTP-binding Ypt1 protein, may act in endoplasmic reticulum-to-Golgi transport.

1991 • 193 citations

Role of Vacuolar Acidification in Protein Sorting and Zymogen Activation: a Genetic Analysis of the Yeast Vacuolar Proton-Translocating ATPase

1990 • 190 citations

Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4

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Assay of vacuolar pH in yeast and identification of acidification-defective mutants.

1989 • 179 citations

Distinct structural elements of rab5 define its functional specificity.

1994 • 163 citations

Protein transport to the vacuole and receptor-mediated endocytosis by clathrin heavy chain-deficient yeast.

1988 • 153 citations

Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment.

1993 • 152 citations

Involvement of Ypt7p, a small GTPase, in traffic from late endosome to the vacuole in yeast

1993 • 150 citations

SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus.

1988 • 145 citations

The ras-related ypt protein is an ubiquitous eukaryotic protein: isolation and sequence analysis of mouse cDNA clones highly homologous to the yeast YPT1 gene.

1987 • 142 citations

The ras-related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.

1989 • 136 citations

The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach

1992 • 120 citations

Partial purification and characterization of early and late endosomes from yeast. Identification of four novel proteins

1993 • 120 citations

In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae.

1992 • 113 citations

Detection of an intermediate compartment involved in transport of alpha-factor from the plasma membrane to the vacuole in yeast.

1990 • 111 citations

Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4

1993 • 105 citations

Mutational analysis of the putative effector domain of the GTP-binding Ypt1 protein in yeast suggests specific regulation by a novel GAP activity.

1991 • 91 citations

Compartment acidification is required for efficient sorting of proteins to the vacuole in Saccharomyces cerevisiae.

1992 • 80 citations

Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins.

1989 • 72 citations

Yeast endocytosis

1993 • 66 citations

The ryh1 gene in the fission yeast Schizosaccharomyces pombe encoding a GTP-binding protein related to ras, rho and ypt: structure, expression and identification of its human homologue.

1990 • 66 citations

The Yeast SLY Gene Products, Suppressors of Defects in the Essential GTP-Binding Ypt1 Protein, May Act in Endoplasmic Reticulum-to-Golgi Transport

1991 • 65 citations

Schizosaccharomyces pombe ypt5: a homologue of the rab5 endosome fusion regulator.

1993 • 31 citations

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