Intestinal γδ T Cells Develop in Mice Lacking Thymus, All Lymph Nodes, Peyer’s Patches, and Isolated Lymphoid Follicles

Expression of the γ-δ T-cell receptor on intestinal CD8+ intraepithelial lymphocytes

1988 • 663 citations

Development of the Primary Antibody Repertoire

1987 • 629 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

The anatomical basis of intestinal immunity

1997 • 493 citations

Thymic Origin of Intestinal αß T Cells Revealed by Fate Mapping of RORγt ⁺ Cells

2004 • 482 citations

Intraepithelial lymphocytes: exploring the Third Way in immunology

2001 • 481 citations

Identification of Multiple Isolated Lymphoid Follicles on the Antimesenteric Wall of the Mouse Small Intestine

2002 • 460 citations

Analysis and Expression of a Cloned Pre-T Cell Receptor Gene

1994 • 410 citations

Identification of novel lymphoid tissues in murine intestinal mucosa where clusters of c-kit+ IL-7R+ Thy1+ lympho-hemopoietic progenitors develop.

1996 • 400 citations

Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

1988 • 394 citations

High-Throughput Genotyping with Single Nucleotide Polymorphisms

2001 • 384 citations

A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice

1994 • 327 citations

Generation of Intestinal T Cells from Progenitors Residing in Gut Cryptopatches

1998 • 301 citations

Lymph Node Genesis Is Induced by Signaling through the Lymphotoxin β Receptor

1998 • 294 citations

IL-7 receptor α+ CD3– cells in the embryonic intestine induces the organizing center of Peyer's patches

1999 • 289 citations

Phenotypic complexity of intraepithelial lymphocytes of the small intestine.

1991 • 252 citations

T cell development in mice lacking the CD3-zeta/eta gene.

1993 • 235 citations

Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides

2002 • 201 citations

Starting at the Beginning: New Perspectives on the Biology of Mucosal T Cells

2004 • 200 citations

Intra-epithelial lymphocytes. Evidence for regional specialization and extrathymic T cell maturation in the human gut epithelium

1995 • 196 citations

Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine.

1993 • 186 citations

Extrathymic T Cell Lymphopoiesis

2003 • 180 citations

Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

1993 • 164 citations

Gut Cryptopatches

2000 • 147 citations

Enterocyte Expression of Interleukin 7 Induces Development of γδ T Cells and Peyer's Patches

2000 • 143 citations

The V–J Recombination of T Cell Receptor-γ Genes Is Blocked in Interleukin-7 Receptor–deficient Mice

1996 • 132 citations

Extrathymic T cell differentiation

1995 • 129 citations

T-cell receptor gamma delta and gamma transgenic mice suggest a role of a gamma gene silencer in the generation of alpha beta T cells.

1990 • 128 citations

Interactions between stem cell factor and c-Kit are required for intestinal immune system homeostasis

1994 • 123 citations

Induction of Germline Transcription in the TCRγ Locus by Stat5

1999 • 120 citations

Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptors.

1993 • 119 citations

Different expression of the recombination activity gene RAG‐1 in various populations of thymocytes, peripheral T cells and gut thymus‐independent intraepithelial lymphocytes suggests two pathways of T cell receptor rearrangement

1992 • 107 citations

Extrathymic T Cell Differentiation in the Human Intestine Early in Life

1998 • 97 citations

Gut intraepithelial lymphocyte development

2002 • 79 citations

Regional Specialization of Intraepithelial T Cells in the Murine Small and Large Intestine

1995 • 79 citations

CD3⁻CD8⁺ intestinal intraepithelial lymphocytes (IEL) and the extrathymic development of IEL

1994 • 78 citations

Role of Gut Cryptopatches in Early Extrathymic Maturation of Intestinal Intraepithelial T Cells

2000 • 75 citations

Expression of genes encoding the pre-TCR and CD3 complex during thymus development

1995 • 71 citations

Age-dependent intestinal lymphoproliferative disorder due to stem cell factor receptor deficiency: parameters in small and large intestine.

1997 • 69 citations

Phenotypic heterogeneity of intraepithelial T lymphocytes from mouse small intestine.

1991 • 67 citations

RAG1 and RAG2 expression in human intestinal epithelium: evidence of extrathymic T cell differentiation

1995 • 57 citations

An accessory role of TCRγ δ+ cells in the exacerbation of inflammatory bowel disease in TCRα mutant mice

2001 • 56 citations

Basic Aspects of Intraepithelial Lymphocyte Immunobiology

1994 • 51 citations

Accessibility Control of V(D)J Recombination: Lessons from Gene Targeting

1998 • 43 citations

Reconstitution of the extrathymic intestinal T cell compartment in the absence of irradiation.

1997 • 38 citations

T lymphocyte development in the absence of CD3 epsilon or CD3 gamma delta epsilon zeta.

1999 • 36 citations

T Lymphocyte Development in the Absence of CD3ε or CD3γδεζ

1999 • 35 citations

Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor αβ lineage

1998 • 34 citations

TCR expression in human fetal intestine and identification of an early T cell receptor beta-chain transcript.

1997 • 27 citations

Identification and characterization of lymphoid precursors in the murine intestinal epithelium

2001 • 21 citations

Evidence for the Extrathymic Origin of Intestinal TCRγδ+ T Cells in Normal Rats and for an Impairment of This Differentiation Pathway in BB Rats

2002 • 18 citations

T cell progenitors in the murine small intestine

1997 • 16 citations

Speculation on the lineage relationships among CD4−8+gut-derived T cells and their role(s)

1999 • 15 citations

Thymus-Independent Development of Gut T Cells

1998 • 11 citations