CD3⁻CD8⁺ intestinal intraepithelial lymphocytes (IEL) and the extrathymic development of IEL

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting

1991 • 892 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures.

1990 • 574 citations

The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation.

1991 • 345 citations

Identification and distribution of the costimulatory receptor CD28 in the mouse.

1992 • 316 citations

IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alpha.

1992 • 285 citations

Intraepithelial lymphocytes modulate Ia expression by intestinal epithelial cells.

1984 • 272 citations

Subsets of CD3⁺ (T cell receptor α/β or γ/δ) and CD3⁻ lymphocytes isolated from normal human gut epithelium display phenotypical features different from their counterparts in peripheral blood

1990 • 269 citations

Thymus-independent development and negative selection of T cells expressing T cell receptor alpha/beta in the intestinal epithelium: evidence for distinct circulation patterns of gut- and thymus-derived T lymphocytes.

1992 • 268 citations

Extrathymic origin of intestinal intraepithelial lymphocytes bearing T-cell antigen receptor gamma delta.

1991 • 262 citations

Phenotypic complexity of intraepithelial lymphocytes of the small intestine.

1991 • 252 citations

Towards an integrated view of thymopoiesis

1991 • 205 citations

Selection of intraepithelial lymphocytes with CD8 alpha/alpha co-receptors by self-antigen in the murine gut.

1992 • 163 citations

Phenotypic and functional stages in the intrathymic development of αβ T cells

1991 • 151 citations

Differentiation and functional maturation of bone marrow-derived intestinal epithelial T cells expressing membrane T cell receptor in athymic radiation chimeras.

1990 • 144 citations

Intraepithelial Lymphocyte Count and Crypt Hyperplasia Measure the Mucosal Component of the Graft-versus-Host Reaction in Mouse Small Intestine

1982 • 142 citations

Immunopathology of the Small Intestine

1987 • 140 citations

Intestinal intraepithelial lymphocytes are activated and cytolytic but do not proliferate as well as other T cells in response to mitogenic signals.

1993 • 117 citations

Different expression of the recombination activity gene RAG‐1 in various populations of thymocytes, peripheral T cells and gut thymus‐independent intraepithelial lymphocytes suggests two pathways of T cell receptor rearrangement

1992 • 107 citations

lnterleukin-2-dependent autocrine proliferation in T-cell development

1989 • 107 citations

Peripheral engraftment of fetal intestine into athymic mice sponsors T cell development: direct evidence for thymopoietic function of murine small intestine.

1992 • 97 citations

Murine intestinal intraepithelial lymphocytes. I. Relationship of a novel Thy‐1−, Lyt‐1⁻, Lyt‐2⁺, granulated subpopulation to natural killer cells and mast cells

1985 • 94 citations

CD4⁺ CD8⁺ murine intestinal intraepithelial Iymphocytes

1990 • 90 citations

Thymus influences the development of extrathymically derived intestinal intraepithelial lymphocytes

1993 • 86 citations

Immunopathology of the small intestine

1987 • 64 citations

Proliferative properties of murine intestinal intraepithelial lymphocytes (IEL): IEL expressing TCRαβ or TCRτδ are largely unresponsive to proliferative signals mediated via conventional stimulation of the CD3-TCR complex

1991 • 61 citations

Lymphokine-activated killer cells. VII. IL-4 induces an NK1.1+CD8 alpha+beta- TCR-alpha beta B220+ lymphokine-activated killer subset.

1993 • 55 citations

Antigen-specific and polyclonal CD4+ lamina propria T-cell lines: phenotypic and functional characterization.

1992 • 51 citations

Two differential pathways from double-negative to double-positive thymocytes.

1991 • 37 citations

Murine intestinal intraepithelial lymphocytes. II. Comparison of freshly isolated and cultured intraepithelial lymphocytes

1985 • 35 citations

Sequential analysis of T cells in the liver during murine listerial infection.

1992 • 27 citations

Factor requirements activation and proliferation steps of human cd2+cd3−cd4−cd8− early thymocytes

1989 • 21 citations

Identification of thymocyte precursors in murine fetal liver

1991 • 17 citations

Sequential appearance of T-cell receptor gamma delta- and alpha beta-bearing intestinal intra-epithelial lymphocytes in mice after irradiation.

1991 • 7 citations

Reply

1993 • 2 citations