Stem Cell Transplants for Hematopoietic Malignancies

Bone Marrow Transplant

2001 • 3,479 citations

Bone marrow transplant

1989 • 3,423 citations

de la Chapelle, A.

1997 • 3,184 citations

Graft-versus-leukemia reactions after bone marrow transplantation

1990 • 2,781 citations

Autologous Bone Marrow Transplantation as Compared with Salvage Chemotherapy in Relapses of Chemotherapy-Sensitive Non-Hodgkin's Lymphoma

1995 • 2,428 citations

Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia [see comments]

1995 • 2,026 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

Outcome of Cord-Blood Transplantation from Related and Unrelated Donors

1997 • 1,272 citations

HSV-TK Gene Transfer into Donor Lymphocytes for Control of Allogeneic Graft-Versus-Leukemia

1997 • 1,180 citations

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation

1993 • 949 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

High-Dose Therapy and Autologous Bone Marrow Transplantation after Failure of Conventional Chemotherapy in Adults with Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma

1987 • 797 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

BCL-6 protein is expressed in germinal-center B cells

1995 • 582 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 582 citations

Superiority of Tandem Autologous Transplantation Over Standard Therapy for Previously Untreated Multiple Myeloma

1997 • 576 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 494 citations

Identification of AML-1 and the (8;21) translocation protein (AML-1/ETO) as sequence-specific DNA-binding proteins: the runt homology domain is required for DNA binding and protein-protein interactions.

1993 • 484 citations

Peripheral blood stem cell transplants for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients

1995 • 459 citations

Unique Forms of the abl Tyrosine Kinase Distinguish Ph ¹ -Positive CML from Ph ¹ -Positive ALL

1987 • 344 citations

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma

1993 • 340 citations

Long-Term Marrow Culture Reveals Chromosomally Normal Hematopoietic Progenitor Cells in Patients with Philadelphia Chromosome-Positive Chronic Myelogenous Leukemia

1983 • 335 citations

Benefit of autologous bone marrow transplantation over sequential chemotherapy in poor-risk aggressive non-Hodgkin's lymphoma: updated results of the prospective study LNH87-2. Groupe d'Etude des Lymphomes de l'Adulte.

1997 • 284 citations

Autologous bone marrow transplantation for acute myelocytic leukemia in first remission: a European survey of the role of marrow purging

1990 • 281 citations

Interleukin-6 Inhibits Fas-Induced Apoptosis and Stress-Activated Protein Kinase Activation in Multiple Myeloma Cells

1997 • 278 citations

Clinical significance of cytogenetics in acute myeloid leukemia.

1997 • 267 citations

Prognostic significance of karyotype in de novo adult acute myeloid leukemia. The BGMT group.

1995 • 254 citations

Prospective comparative trial of autologous versus allogeneic bone marrow transplantation in patients with non-Hodgkin's lymphoma

1994 • 233 citations

High-dose therapy and autologous bone marrow transplantation in patients with follicular lymphoma during first remission

1996 • 223 citations

Use of Partially Mismatched Related Donors Extends Access to Allogeneic Marrow Transplant

1997 • 220 citations

Cytogenetic analysis of 434 consecutively ascertained specimens of non- Hodgkin's lymphoma: clinical correlations

1991 • 217 citations

Detection of the chromosomal translocation t(11;14) by polymerase chain reaction in mantle cell lymphomas

1994 • 207 citations

Advances in Internal Medicine.

1962 • 191 citations

Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow

1994 • 182 citations

There are differences in cytogenetic abnormalities among histologic subtypes of the non-Hodgkin's lymphomas

1985 • 178 citations

Low-risk intensive therapy for multiple myeloma with combined autologous bone marrow and blood stem cell support

1992 • 177 citations

Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level.

1992 • 174 citations

Autologous marrow transplantation for malignant lymphoma: a report of 101 cases from Seattle.

1990 • 174 citations

Preceding standard therapy is the likely cause of MDS after autotransplants for multiple myeloma

1996 • 164 citations

Toward a clinically relevant cytogenetic classification of acute myelogenous leukemia

1987 • 160 citations

Involvement of Fas-Mediated Apoptosis in the Inhibitory Effects of Interferon-α in Chronic Myelogenous Leukemia

1997 • 152 citations

Successful autografting in chronic myeloid leukaemia after maintenance of marrow in culture.

1989 • 149 citations

Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells

1995 • 146 citations

Low-risk intensive therapy for multiple myeloma with combined autologous bone marrow and blood stem cell support

1992 • 143 citations

Long-term survival in acute myelogenous leukemia

1994 • 141 citations

In vivo induction of gamma interferon and tumor necrosis factor by interleukin-2 infusion following intensive chemotherapy or autologous marrow transplantation

1989 • 122 citations

Clinical impact of chemotherapy dose escalation in patients with hematologic malignancies and solid tumors.

1997 • 108 citations

Prevention of Graft-Versus-Host Disease in Mice Using a Suicide Gene Expressed in T Lymphocytes

1997 • 93 citations

Relapse of multiple myeloma after autologous transplantation: survival after salvage therapy.

1995 • 91 citations

Advances in Internal Medicine.

1979 • 90 citations

Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogene.

1991 • 89 citations

Thymidine Kinase (TK) Gene-Transduced Human Lymphocytes Can Be Highly Purified, Remain Fully Functional, and Are Killed Efficiently With Ganciclovir

1997 • 89 citations

Treatment of chronic myeloid leukemia with allogeneic bone marrow transplantation after preparation with BuCy2

1992 • 88 citations

Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells.

1991 • 85 citations

Prognostic impact of karyotype and immunologic phenotype in 125 adult patients with de novo AML

1992 • 78 citations

Characterization of the alloreactivity and anti-leukemia reactivity of cord blood mononuclear cells.

1995 • 78 citations

Effective graft-versus-leukemia effects independent of graft-versus-host disease after T cell-depleted allogeneic bone marrow transplantation in a murine model of B cell leukemia/lymphoma. Role of cell therapy and recombinant IL-2.

1994 • 70 citations

Bone marrow transplantation with interleukin-2-activated bone marrow followed by interleukin-2 therapy for acute myeloid leukemia in mice

1990 • 61 citations

Amifostine improves the antileukemic therapeutic index of mafosfamide: implications for bone marrow purging

1995 • 59 citations

In vitro and in vivo assessment of the graft-versus-leukemia activity of cord blood.

1995 • 59 citations

Salvage therapy for relapsed or refractory non-Hodgkin's lymphoma utilizing autologous bone marrow transplantation

1989 • 52 citations

Anti-IL-4 antibody prevents graft-versus-host disease in mice after bone marrow transplantation. The IgE allotype is an important marker of graft-versus-host disease.

1995 • 47 citations

Gene Marking and Autologous Bone Marrow Transplantationa

1994 • 42 citations

Transforming growth factor-β3 protection of epithelial cells from cycle-selective chemotherapy in vitro

1997 • 31 citations

Marrow transplantation following busulfan and cyclophosphamide for chronic myelogenous leukaemia in accelerated or blastic phase

1989 • 29 citations

Cord blood transplantation: implications for graft vs. host disease and graft vs. leukemia.

1994 • 28 citations

Peripheral stem cell mobilization and engraftment in patients over age 60

1997 • 27 citations

Use of gene marking in bone marrow transplantation.

1996 • 22 citations

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma

1993 • 19 citations

Soluble Interleukin-2 Receptor, Soluble CD8 and Soluble Intercellular Adhesion Molecule-1 Levels in Hematologic Malignancies

1994 • 18 citations

Busulfan and Cyclophosphamide Versus Cyclophosphamide and Total Body Irradiation for Marrow Transplantation in Chronic Myelogenous Leukemia–A Review

1993 • 17 citations

Advances in the treatment of multiple myeloma.

1998 • 13 citations

Monitoring minimal residual disease.

1993 • 11 citations

Increased IgE Level as a Marker of Host-versus-Graft Disease: Inhibition of This HVGD with a Monoclonal Antibody to IL-4

1993 • 9 citations

Serum soluble IL-2 receptor as a reliable and noninvasive marker of disease activity in patients with hairy cell leukemia.

1996 • 8 citations

The development of bone marrow transplantation as a treatment for patients with lymphoma--twentieth Richard and Hinda Rosenthal Foundation Award Lecture.

1997 • 4 citations