Detection of residual lymphoma cells by polymerase chain reaction in peripheral blood is significantly less predictive for relapse than detection in bone marrow

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Analysis of Survival Data

1984 • 6,206 citations

Avoiding false positives with PCR

1989 • 3,564 citations

Cloning of the Chromosome Breakpoint of Neoplastic B Cells with the t(14;18) Chromosome Translocation

1984 • 1,761 citations

Fundamentals of Biostatistics.

1992 • 1,208 citations

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around Jh on chromosome 14 and near a transcriptional unit on 18

1985 • 1,188 citations

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1985 • 972 citations

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation

1993 • 949 citations

Immunologic Purging of Marrow Assessed by PCR before Autologous Bone Marrow Transplantation for B-Cell Lymphoma

1991 • 712 citations

Molecular Analysis of the T(14;18) Chromosomal Translocation in Malignant Lymphomas

1987 • 701 citations

Distinctive Chromosomal Abnormalities in Histologic Subtypes of Non-Hodgkin's Lymphoma

1982 • 642 citations

Simple and Rapid Preparation of Samples for PCR

1989 • 596 citations

All advanced stage non-Hodgkin's lymphomas with a polymerase chain reaction amplifiable breakpoint of bcl-2 have residual cells containing the bcl-2 rearrangement at evaluation and after treatment

1991 • 347 citations

Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas.

1986 • 346 citations

Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.

1988 • 341 citations

Detection by polymerase chain reaction of residual cells with the bcl-2 translocation is associated with increased risk of relapse after autologous bone marrow transplantation for B-cell lymphoma

1993 • 340 citations

Detection of minimal disease in hematopoietic malignancies of the B-cell lineage by using third-complementarity-determining region (CDR-III)-specific probes.

1989 • 283 citations

Detection of Small Numbers of Monoclonal B Lymphocytes in the Blood of Patients with Lymphoma

1979 • 164 citations

The significance of circulating cells carrying t(14;18) in long remission from follicular lymphoma.

1991 • 153 citations

Significance of detection of occult non-Hodgkin's lymphoma in histologically uninvolved bone marrow by a culture technique

1992 • 120 citations

The gene located at chromosome 18 band q21 is rearranged in uncultured diffuse lymphomas as well as follicular lymphomas

1987 • 105 citations

Persistence of circulating t(14;18)-positive cells in long-term remission after radiation therapy for localized-stage follicular lymphoma.

1993 • 86 citations

Detection of occult lymphoma in the peripheral blood and bone marrow of patients with untreated early-stage and advanced-stage follicular lymphoma.

1993 • 74 citations

Derivation of lymphoma cell lines from microscopically normal bone marrow in patients with undifferentiated lymphomas: evidence of occult bone marrow involvement

1983 • 71 citations

DETECTION OF B-CELL LYMPHOMA IN PERIPHERAL BLOOD BY DNA HYBRIDISATION

1985 • 61 citations

Molecular detection of residual lymphoma cells in peripheral blood stem cell harvests and following autologous transplantation.

1993 • 50 citations

Detection of bcl-2/JH rearrangement in follicular and diffuse lymphoma: concordant results of peripheral blood and bone marrow analysis at diagnosis

1993 • 42 citations

Detection of non-Hodgkin's lymphoma in the peripheral blood by analysis of antigen receptor gene rearrangements: results of a prospective study

1990 • 33 citations

Detection of residual disease in translocation (14;18) positive non-Hodgkin's lymphoma, using the polymerase chain reaction: a comparison with conventional staging methods.

1992 • 28 citations

Molecular monitoring of low grade non-Hodgkin's lymphoma by gene amplification

1991 • 22 citations

Adhesion of Follicular Lymphoma Cells to Lymphoid Germinal Centers—A Potential Mechanism of Tumor Cell Homing Following Autologous Transplantation

1994 • 11 citations