Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells

Isolation of a candidate human hematopoietic stem-cell population.

1992 • 1,098 citations

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1981 • 959 citations

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation

1993 • 949 citations

Effect of peripheral-blood progenitor cells mobilised by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy

1992 • 900 citations

GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR TO HARVEST CIRCULATING HAEMOPOIETIC STEM CELLS FOR AUTOTRANSPLANTATION

1989 • 776 citations

Immunologic Purging of Marrow Assessed by PCR before Autologous Bone Marrow Transplantation for B-Cell Lymphoma

1991 • 712 citations

Genetic marking shows that Ph+ cells present in autologous transplants of chronic myelogenous leukemia (CML) contribute to relapse after autologous bone marrow in CML

1994 • 502 citations

Expression of Thy-1 on human hematopoietic progenitor cells.

1993 • 477 citations

Peripheral blood stem cell transplants for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients

1995 • 459 citations

Transplantation of enriched CD34-positive autologous marrow into breast cancer patients following high-dose chemotherapy: influence of CD34-positive peripheral-blood progenitors and growth factors on engraftment.

1994 • 402 citations

Phenotypic difference of normal plasma cells from mature myeloma cells

1993 • 323 citations

The bone marrow of multiple myeloma patients contains B cell populations at different stages of differentiation that are clonally related to the malignant plasma cell.

1993 • 248 citations

Successful autologous transplantation of blood stem cells mobilized with recombinant human granulocyte-macrophage colony-stimulating factor.

1990 • 230 citations

Development of a highly sensitive assay, based on the polymerase chain reaction, for rare B‐lymphocyte clones in a polyclonal population

1990 • 224 citations

Implantation and maintenance of functional human bone marrow in SCID-hu mice

1992 • 209 citations

Enrichment of human hematopoietic stem cell activity in the CD34+Thy- 1+Lin- subpopulation from mobilized peripheral blood

1995 • 205 citations

INTENSIVE TREATMENT OF MULTIPLE MYELOMA AND CRITERIA FOR COMPLETE REMISSION

1989 • 204 citations

Low-risk intensive therapy for multiple myeloma with combined autologous bone marrow and blood stem cell support

1992 • 177 citations

Detection and quantitation of malignant cells in the peripheral blood of multiple myeloma patients

1992 • 174 citations

Monoclonal lymphocyte population in human plasma cell myeloma.

1974 • 173 citations

Lymphoid reconstitution of the human fetal thymus in SCID mice with CD34+ precursor cells.

1991 • 173 citations

Characterization of primitive hematopoietic cells in normal human peripheral blood

1992 • 172 citations

Hematopoietic growth factors and human megakaryocyte differentiation.

1992 • 172 citations

High-dose therapy for refractory multiple myeloma: improved prognosis with better supportive care and double transplants

1994 • 172 citations

Positively selected autologous blood CD34+ cells and unseparated peripheral blood progenitor cells mediate identical hematopoietic engraftment after high-dose VP16, ifosfamide, carboplatin, and epirubicin

1994 • 162 citations

Intensive combined therapy for previously untreated aggressive myeloma

1992 • 151 citations

Monoclonal Circulating B Cells in Multiple Myeloma

1992 • 148 citations

Evidence for peripheral blood B lymphocyte but not T lymphocyte involvement in multiple myeloma

1987 • 146 citations

Interleukin-6 gene expression in multiple myeloma: a characteristic of immature tumor cells

1993 • 141 citations

High-dose chemoradiotherapy and autologous blood stem cell transplantation in multiple myeloma: results of a phase II trial involving 63 patients

1993 • 138 citations

Analysis of B-lymphoid malignancies using allele-specific polymerase chain reaction: a technique for sequential quantitation of residual disease

1991 • 134 citations

Double-intensive therapy in high-risk multiple myeloma

1992 • 133 citations

Human CD34+ HLA-DR- bone marrow cells contain progenitor cells capable of self-renewal, multilineage differentiation, and long-term in vitro hematopoiesis.

1991 • 132 citations

Selective expression of CD45 isoforms defines CALLA+ monoclonal B- lineage cells in peripheral blood from myeloma patients as late stage B cells

1991 • 129 citations

Thiotepa, busulfan, and cyclophosphamide: a new preparative regimen for autologous marrow or blood stem cell transplantation in high-risk multiple myeloma

1993 • 128 citations

Significance of detection of occult non-Hodgkin's lymphoma in histologically uninvolved bone marrow by a culture technique

1992 • 120 citations

Circulating monoclonal B cells expressing P glycoprotein may be a reservoir of multidrug-resistant disease in multiple myeloma

1994 • 118 citations

The Monoclonal Nature of Lymphocytes in Multiple Myeloma

1975 • 107 citations

Detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin hypervariable region specific oligonucleotide probes

1990 • 89 citations

Follow‐up of residual disease (MRD) in B lineage acute leukaemias using a simplified PCR strategy: evolution of MRD rather than its detection is correlated with clinical outcome

1991 • 85 citations

Clonogenicity of circulating neuroblastoma cells: implications regarding peripheral blood stem cell transplantation

1994 • 84 citations

Coexistence of aneuploid subclones within a myeloma cell line that exhibits clonal immunoglobulin gene rearrangement: clinical implications.

1993 • 73 citations

Idiotypic peripheral blood lymphocytes in monoclonal gammopathy.

1982 • 64 citations

Cellular origin and extent of clonal involvement in multiple myeloma: genetic and phenotypic studies

1994 • 58 citations

Immunomagnetic purging of breast cancer from bone marrow for autologous transplantation.

1991 • 56 citations

Granulocyte colony‐stimulating factor (G‐CSF)‐induced mobilization of circulating haemopoietic stem cells

1993 • 35 citations

The idiotypic specificities of lymphocytes in human monoclonal gammopathies: analysis with the fluorescence activated cell sorter.

1983 • 31 citations

High-dose therapy in multiple myeloma: A prospective randomized study of the “intergroupe français du myelome”

1996 • 27 citations

Peripheral blood stem cell mobilization after stem cell factor or G-CSF treatment: rapid enrichment for stem and progenitor cells using the CEPRATE immunoaffinity separation system.

1992 • 21 citations

High dose chemoradiotherapy and autologous blood stem cell transplantation in multiple myeloma.

1991 • 13 citations

Depletion of T lymphocytes from human bone marrow by the use of counterflow elutriation centrifugation

1986 • 8 citations

Human macrophage colony-stimulating factor induces macrophage colonies after L-phenylalanine methylester treatment of human marrow

1990 • 7 citations

PROGNOSTIC FACTORS IN PURGED MARROW FROM PATIENTS WITH NEUROBLASTOMA RECEIVING MYELOABLATIVE TREATMENT - TUMOR-CELL NUMBER, N-MYC PROTEIN, N-MYC GENE AMPLIFICATION AND RATE OF HEMATOLOGIC RECOVERY

1993 • 3 citations