Gene Marking and Autologous Bone Marrow Transplantationa

Gene-marking to trace origin of relapse after autologous bone-marrow transplantation

1993 • 949 citations

Human gene therapy comes of age

1992 • 927 citations

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

1991 • 897 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 582 citations

Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transfer.

1992 • 544 citations

Identification of breakpoints in t(8;21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt

1992 • 494 citations

Autologous Bone Marrow Transplantation in Patients with Acute Nonlymphocytic Leukemia, Using ex Vivo Marrow Treatment with 4-Hydroperoxycyclophosphamide

1986 • 454 citations

Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients

1993 • 434 citations

Autologous bone marrow transplantation for acute myelocytic leukemia in first remission: a European survey of the role of marrow purging

1990 • 281 citations

Autologous bone marrow transplantation in acute leukemia: a phase I study of in vitro treatment of marrow with 4- hydroperoxycyclophosphamide to purge tumor cells

1985 • 211 citations

Safety Issues Related to Retroviral-Mediated Gene Transfer in Humans

1991 • 207 citations

Detection of DNA rearrangements in the AML1 and ETO loci and of an AML1/ETO fusion mRNA in patients with t(8;21) acute myeloid leukemia

1993 • 193 citations

Long-term expression of human adenosine deaminase in rhesus monkeys transplanted with retrovirus-infected bone-marrow cells.

1992 • 190 citations

The immunologic detection of minimal residual disease in acute leukemia [published erratum appears in Blood 1990 Nov 1;76(7):1901]

1990 • 186 citations

TRANSPLANTATION OF UNPURGED AUTOLOGOUS BONE-MARROW IN ACUTE MYELOID LEUKAEMIA IN FIRST REMISSION

1984 • 139 citations

Autologous bone marrow transplantation using marrow incubated with Asta Z 7557 in adult acute leukemia

1986 • 138 citations

High-dose chemoradiotherapy supported by marrow infusions for advanced neuroblastoma: a Pediatric Oncology Group study.

1991 • 124 citations

The ADA Human Gene Therapy Clinical Protocol Original Covering Memo: February 23, 1990

1990 • 96 citations

An approach for the analysis of relapse and marrow reconstitution after autologous marrow transplantation using retrovirus-mediated gene transfer

1992 • 87 citations

Overview of the clinical relevance of autologous bone marrow transplantation

1986 • 80 citations

An approach for the analysis of relapse and marrow reconstitution after autologous marrow transplantation using retrovirus-mediated gene transfer

1992 • 80 citations

Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs

1991 • 78 citations

Retroviral vector-mediated high-efficiency expression of adenosine deaminase (ADA) in hematopoietic long-term cultures of ADA-deficient marrow cells.

1989 • 73 citations

Gene transfer to primary normal and malignant human hemopoietic progenitors using recombinant retroviruses

1987 • 69 citations

Retrovirus-mediated gene transduction into long-term repopulating marrow cells of dogs

1991 • 68 citations

Autologous Bone Marrow Transplantation

1989 • 62 citations

Retrovirus-Mediated Gene Transfer as an Approach to Analyze Neuroblastoma Relapse after Autologous Bone Marrow Transplantation

1992 • 57 citations

Autologous bone marrow transplantation following high dose chemotherapy for the treatment of adult patients with acute myeloid leukaemia

1986 • 57 citations

The prognostic significance of autologous bone marrow transplant in advanced neuroblastoma.

1991 • 55 citations

The definition of remission in acute leukemia with immunologic techniques.

1991 • 53 citations

Retroviral vector-mediated transfer of the bacterial neomycin resistance gene into fetal and adult sheep and human hematopoietic progenitors in vitro

1990 • 47 citations

Expression of a foreign gene in cats reconstituted with retroviral vector infected autologous bone marrow

1991 • 45 citations

Production of human glucocerebrosidase in mice after retroviral gene transfer into multipotential hematopoietic progenitor cells.

1989 • 41 citations

Monoclonal antibody purging and autologous bone marrow transplantation in acute myelogenous leukemia in complete remission.

1989 • 24 citations

Selective purging by human interleukin‐2 activated lymphocytes of bone marrows contaminated with a lymphoma line or autologous leukaemic cells

1991 • 22 citations

Retroviral Vector-Mediated Gene Transfer into Hematopoietic Cells: Prospects and Issues

1992 • 19 citations

Allogeneic and autologous bone marrow transplantation for acute leukemia and malignant lymphoma: Current status

1987 • 10 citations

Long-Term Expression of the Human ß-Globin Gene After Retroviral Transfer into Pluripotent Hematopoietic Stem Cells of the Mouse

1989 • 9 citations

Monoclonal antibody purging and autologous bone marrow transplantation in acute myelogenous leukemia in complete remission.

1989 • 8 citations

Introduction and expression of human beta globin genes into primitive murine hematopoietic progenitor cells by retrovirus mediated gene transfer.

1989 • 4 citations