Thymidine Kinase (TK) Gene-Transduced Human Lymphocytes Can Be Highly Purified, Remain Fully Functional, and Are Killed Efficiently With Ganciclovir

Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients

1990 • 1,544 citations

Antileukemic Effect of Graft-versus-Host Disease in Human Recipients of Allogeneic-Marrow Grafts

1979 • 1,538 citations

Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction

1990 • 1,307 citations

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

1993 • 1,097 citations

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy.

1986 • 962 citations

T-cell depletion of HLA-identical transplants in leukemia

1991 • 771 citations

Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia [published erratum appears in Blood 1989 Aug 15;74(3):1180]

1989 • 623 citations

Graft-versus-myeloma effect: proof of principle

1996 • 565 citations

Induction of Graft-versus-Host Disease as Immunotherapy for Relapsed Chronic Myeloid Leukemia

1994 • 510 citations

Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation

1988 • 483 citations

Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia [published erratum appears in Blood 1989 Aug 15;74(3):1180]

1989 • 448 citations

Epstein-Barr virus lymphoproliferation after bone marrow transplantation

1988 • 420 citations

Ganciclovir

1990 • 399 citations

Allogeneic Bone Marrow Transplantation in Multiple Myeloma

1991 • 389 citations

Graft-versus-Host Disease as Adoptive Immunotherapy in Patients with Advanced Hematologic Neoplasms

1989 • 361 citations

Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: efficacy and toxicity of a defined T-cell dose

1993 • 356 citations

HOW DOES BONE-MARROW TRANSPLANTATION CURE LEUKAEMIA?

1984 • 277 citations

Targeting of an inducible toxic phenotype in animal cells.

1988 • 252 citations

Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation?

1994 • 220 citations

T CELL DEPLETION WITH CAMPATH-1 IN ALLOGENEIC BONE MARROW TRANSPLANTATION

1988 • 189 citations

T-cell-depleted allogeneic bone marrow transplantation for acute leukaemia using Campath-1 antibodies and post-transplant administration of donor's peripheral blood lymphocytes for prevention of relapse

1995 • 167 citations

Graft rejection following HLA matched T‐lymphocyte depleted bone marrow transplantation

1986 • 163 citations

Graft-versus-leukaemia reactivity induced by alloimmunisation without augmentation of graft-versus-host reactivity

1979 • 157 citations

Transfer of the HSV-tk Gene into Donor Peripheral Blood Lymphocytes for In Vivo Modulation of Donor Anti-Tumor Immunity after Allogeneic Bone Marrow Transplantation. The San Raffaele Hospital, Milan, Italy

1995 • 147 citations

Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow.

1992 • 146 citations

Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies

1991 • 133 citations

INCREASING UTILIZATION OF BONE MARROW TRANSPLANTATION

1986 • 92 citations

Phase I Study of Cellular Adoptive Immunotherapy Using Genetically Modified CD8⁺ HIV-Specific T Cells for HIV Seropositive Patients Undergoing Allogeneic Bone Marrow Transplant. Fred Hutchinson Cancer Research Center and the University of Washington

1992 • 90 citations

Adoptive immunotherapy using donor leukocytes following bone marrow transplantation for chronic myeloid leukemia: is T cell dose important in determining biological response?

1995 • 86 citations

HLA-identical marrow transplantation during accelerated-phase chronic myelogenous leukemia: analysis of survival and remission duration

1988 • 78 citations

Second marrow transplants in patients with leukemia who relapse after allogeneic marrow transplantation.

1988 • 64 citations

Time pattern of the antileukemic effect of graft-versus-host reaction in mice.

1971 • 56 citations