Transforming Growth Factor-β1 Polarizes Murine Hematopoietic Progenitor Cells to Generate Langerhans Cell-Like Dendritic Cells Through a Monocyte/Macrophage Differentiation Pathway

Dendritic cells and the control of immunity

1998 • 14,345 citations

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

1998 • 2,916 citations

A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function

1997 • 2,257 citations

Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells

1996 • 1,908 citations

GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

1992 • 1,608 citations

Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

1998 • 1,448 citations

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

1997 • 1,143 citations

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

1996 • 1,129 citations

Defective haematopoiesis and vasculogenesis in transforming growth factor-β1 knock out mice

1995 • 1,020 citations

CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha.

1996 • 962 citations

TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor

1997 • 869 citations

Maturation Stages of Mouse Dendritic Cells in Growth Factor–dependent Long-Term Cultures

1997 • 860 citations

Regulation of MHC Class II Expression by Interferon-γ Mediated by the Transactivator Gene CIITA

1994 • 854 citations

Developmental regulation of MHC class II transport in mouse dendritic cells

1997 • 754 citations

Ueber die Nerven der menschlichen Haut

1868 • 678 citations

Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.

1998 • 627 citations

Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.

1994 • 626 citations

Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes.

1997 • 524 citations

Transforming Growth Factor β1, in the Presence of Granulocyte/Macrophage Colony-stimulating Factor and Interleukin 4, Induces Differentiation of Human Peripheral Blood Monocytes into Dendritic Langerhans Cells

1998 • 507 citations

Cutting Edge: Differential Regulation of Chemokine Receptors During Dendritic Cell Maturation: A Model for Their Trafficking Properties

1998 • 486 citations

In utero manipulation of coat color formation by a monoclonal anti-c-kit antibody: two distinct waves of c-kit-dependency during melanocyte development.

1991 • 479 citations

A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells

1996 • 479 citations

Langerhans' cells, veiled cells, and interdigitating cells in the mouse recognized by a monoclonal antibody.

1986 • 478 citations

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

1997 • 455 citations

CD34+ Hematopoietic Progenitors From Human Cord Blood Differentiate Along Two Independent Dendritic Cell Pathways in Response to Granulocyte-Macrophage Colony-Stimulating Factor Plus Tumor Necrosis Factor α: II. Functional Analysis

1997 • 442 citations

Activation of human dendritic cells following infection with Mycobacterium tuberculosis.

1997 • 430 citations

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets

1994 • 391 citations

Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma

1997 • 384 citations

Mice Lacking the MHC Class II Transactivator (CIITA) Show Tissue-Specific Impairment of MHC Class II Expression

1996 • 356 citations

Characterization of dermal dendritic cells obtained from normal human skin reveals phenotypic and functionally distinctive subsets.

1993 • 347 citations

Serum contains a platelet-derived transforming growth factor.

1982 • 330 citations

TGF-beta 1 promotes in vitro development of dendritic cells from CD34+ hemopoietic progenitors.

1996 • 312 citations

Transforming growth factor β: a matter of life and death

1994 • 306 citations

Dendritic Cells Enhance Growth and Differentiation of CD40-activated B Lymphocytes

1997 • 301 citations

Identification of dendritic cell colony-forming units among normal human CD34+ bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte/macrophage colony-stimulating factor and tumor necrosis factor alpha.

1995 • 296 citations

Human and murine dermis contain dendritic cells. Isolation by means of a novel method and phenotypical and functional characterization.

1993 • 279 citations

Autoimmunity associated with TGF-beta1-deficiency in mice is dependent on MHC class II antigen expression.

1996 • 236 citations

Identification of macrophages and dendritic cells in the osteopetrotic (op/op) mouse

1993 • 233 citations

Tumor Necrosis Factors: Gene Structure and Biological Activities

1986 • 215 citations

BLOCKADE OF THE CD40-CD40 LIGAND PATHWAY POTENTIATES THE CAPACITY OF DONOR-DERIVED DENDRITIC CELL PROGENITORS TO INDUCE LONG-TERM CARDIAC ALLOGRAFT SURVIVAL1,2

1997 • 215 citations

Contrasting Effects of TGF‐β1 and TNF‐α on the Development of Dendritic Cells from Progenitors in Mouse Bone Marrow

1997 • 214 citations

Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells

1996 • 204 citations

Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype.

1993 • 181 citations

Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1.

1995 • 174 citations

Thymic dendritic cells

1997 • 163 citations

CD40 Ligation on Human Cord Blood CD34+Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells

1997 • 161 citations

Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation.

1996 • 160 citations

Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene.

1998 • 156 citations

TGFβ in prostate cancer: A growth inhibitor that can enhance tumorigenicity

1997 • 150 citations

Identification of Distinct Regions of 5′ Flanking DNA That Mediate Constitutive, IFN-γ, STAT1, and TGF-β-Regulated Expression of the Class II Transactivator Gene

1998 • 131 citations

TGF-beta attenuates the class II transactivator and reveals an accessory pathway of IFN-gamma action.

1997 • 127 citations

Interleukin-3 cooperates with tumor necrosis factor alpha for the development of human dendritic/Langerhans cells from cord blood CD34+ hematopoietic progenitor cells

1996 • 117 citations

Murine epidermal Langerhans cells and splenic dendritic cells present tumor‐associated antigens to primed T cells

1994 • 104 citations

DEC-205, a 205-kDa Protein Abundant on Mouse Dendritic Cells and Thymic Epithelium That Is Detected by the Monoclonal Antibody NLDC-145: Purification, Characterization, and N-Terminal Amino Acid Sequence

1995 • 100 citations

Cloning of Human and Mouse EBI1, a Lymphoid-Specific G-Protein-Coupled Receptor Encoded on Human Chromosome 17q12-q21.2

1994 • 100 citations

Transforming growth factor-beta enhances the M-CSF and GM-CSF-stimulated proliferation of macrophages.

1992 • 82 citations

Expression of E‐cadherin by murine dendritic cells: E‐cadherin as a dendritic cell differentiation antigen characteristic of epidermal Langerhans cells and related cells

1994 • 82 citations

Bifurcated Dendritic Cell Differentiation In Vitro From Murine Lineage Phenotype-Negative c-kit+ Bone Marrow Hematopoietic Progenitor Cells

1998 • 79 citations

Intracoronary adenovirus-mediated transfer of immunosuppressive cytokine genes prolongs allograft survival

1997 • 75 citations

Renal Cell Carcinomas Produce IL-6, IL-10, IL-11, and TGF-β1 in Primary Cultures and Modulate T Lymphocyte Blast Transformation

1997 • 62 citations

Expression of an antisense transforming growth factor-beta1 transgene reduces tumorigenicity of EMT6 mammary tumor cells.

1997 • 58 citations

Gene Transfer of Transforming Growth Factor-β1 Prolongs Murine Cardiac Allograft Survival by Inhibiting Cell-Mediated Immunity

1996 • 55 citations

Induction of Dendritic Cell Differentiation by Granulocyte-Macrophage Colony-Stimulating Factor, Stem Cell Factor, and Tumor Necrosis Factor α In Vitro From Lineage Phenotypes-Negative c-kit+ Murine Hematopoietic Progenitor Cells

1997 • 52 citations

Induction of Dendritic Cell Differentiation by Granulocyte-Macrophage Colony-Stimulating Factor, Stem Cell Factor, and Tumor Necrosis Factor α In Vitro From Lineage Phenotypes-Negative c-kit+ Murine Hematopoietic Progenitor Cells

1997 • 49 citations

Transforming Growth Factor-β System and Its Regulation by Members of the Steroid-Thyroid Hormone Superfamily

1996 • 31 citations