Human blood contains two subsets of dendritic cells, one immunologically mature and the other immature.

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1973 • 2,286 citations

Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro.

1985 • 1,141 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1974 • 1,041 citations

Epidermal Langerhans cells are derived from cells originating in bone marrow

1979 • 879 citations

IDENTIFICATION OF A NOVEL CELL TYPE IN PERIPHERAL LYMPHOID ORGANS OF MICE

1974 • 694 citations

Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ.

1990 • 670 citations

Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal.

1993 • 622 citations

Human neutrophil Fc gamma receptor distribution and structure.

1982 • 577 citations

Migration of dendritic leukocytes from cardiac allografts into host spleens. A novel pathway for initiation of rejection.

1990 • 561 citations

The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.

1990 • 561 citations

Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells.

1989 • 542 citations

Downregulation of the antigen presenting cell function(s) of pulmonary dendritic cells in vivo by resident alveolar macrophages.

1993 • 540 citations

Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells.

1987 • 523 citations

The distinct surface of human blood dendritic cells, as observed after an improved isolation method.

1990 • 402 citations

Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium.

1993 • 395 citations

Human dendritic cells. Enrichment and characterization from peripheral blood

1982 • 389 citations

Cultured Human Langerhans Cells Resemble Lymphoid Dendritic Cells in Phenotype and Function

1989 • 376 citations

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

1992 • 285 citations

Antigen acquisition by dendritic cells: intestinal dendritic cells acquire antigen administered orally and can prime naive T cells in vivo.

1993 • 284 citations

The B7/BB1 antigen provides one of several costimulatory signals for the activation of CD4+ T lymphocytes by human blood dendritic cells in vitro.

1992 • 273 citations

Isolation and characterization of human peripheral blood dendritic cells.

1993 • 240 citations

Prevention of rejection of murine islet allografts by pretreatment with anti-dendritic cell antibody.

1984 • 216 citations

Dendritic cells stimulate primary human cytolytic lymphocyte responses in the absence of CD4+ helper T cells.

1990 • 210 citations

Mouse epidermal Ia molecules have a bone marrow origin

1979 • 203 citations

Inhibition of the immunosuppressive activity of resident pulmonary alveolar macrophages by granulocyte/macrophage colony-stimulating factor.

1993 • 170 citations

Accessory cell requirements for the mixed-leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells

1988 • 147 citations

Use of the fluorescence activated cell sorter to enrich dendritic cells from mouse spleen

1990 • 108 citations

Monoclonal antibody M195: a diagnostic marker for acute myelogenous leukemia.

1989 • 102 citations

T Cell Priming In Situ by Intratracheally Instilled Antigen-pulsed Dendritic Cells

1993 • 44 citations

Identification of potent mixed leukocyte reaction-stimulatory cells in human bone marrow. Putative differentiation stage of human blood dendritic cells.

1993 • 31 citations