Regulatory T Cells Dampen Pulmonary Inflammation and Lung Injury in an Animal Model ofPneumocystisPneumonia

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

2005 • 4,165 citations

The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

2017 • 4,003 citations

The expanding universe of T-cell subsets: Th1, Th2 and more

1996 • 3,710 citations

Regulatory T cells, tumour immunity and immunotherapy

2006 • 2,009 citations

Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17

2003 • 1,828 citations

Positive Effects of Combined Antiretroviral Therapy on CD4 ⁺ T Cell Homeostasis and Function in Advanced HIV Disease

1997 • 1,812 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3

2005 • 957 citations

FOXP3: Of Mice and Men

2005 • 929 citations

Regulatory T cells: friend or foe in immunity to infection?

2004 • 705 citations

Cytokine-induced differentiation of precursor mouse CD8+ T cells into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines

1995 • 686 citations

The Risk ofPneumocystis cariniiPneumonia among Men Infected with Human Immunodeficiency Virus Type 1

1990 • 682 citations

Cytokines and Chemokines

2010 • 534 citations

Current Epidemiology ofPneumocystisPneumonia

2004 • 420 citations

CD4+CD25+ T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function

2005 • 397 citations

Inflammatory Reactions in HIV-1–Infected Persons after Initiation of Highly Active Antiretroviral Therapy

2000 • 388 citations

Depletion of Regulatory T Cells in HIV Infection Is Associated with Immune Activation

2005 • 365 citations

Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients

2005 • 337 citations

HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells

2004 • 308 citations

Immune reconstitution inflammatory syndrome: more answers, more questions

2005 • 279 citations

CD25⁺CD4⁺regulatory T cells suppress CD4⁺T cell‐mediated pulmonary hyperinflammation driven byPneumocystis cariniiin immunodeficient mice

2002 • 276 citations

Tolerance induced by inhaled antigen involves CD4+ T cells expressing membrane-bound TGF-β and FOXP3

2004 • 265 citations

Role of regulatory T cells in human diseases

2005 • 261 citations

A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.

1990 • 250 citations

CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice

2002 • 245 citations

Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice.

1990 • 242 citations

CD4+CD25+ Regulatory T Cells Suppress Differentiation and Functions of Th1 and Th2 Cells, Leishmania major Infection, and Colitis in Mice

2003 • 230 citations

Tolerance induced by inhaled antigen involves CD4+ T cells expressing membrane-bound TGF-β and FOXP3

2004 • 230 citations

Significant Involvement of CCL2 (MCP‐1) in Inflammatory Disorders of the Lung

2003 • 214 citations

Granulocyte Colony-Stimulating Factor: A Novel Mediator of T Cell Tolerance

2005 • 205 citations

CD4+CD25+ Regulatory T Cells Control Innate Immune Reactivity after Injury

2005 • 185 citations

Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-

2006 • 172 citations

Upregulation of Two Death Pathways of Perforin/Granzyme and FasL/Fas in Septic Acute Respiratory Distress Syndrome

2000 • 168 citations

Immune-mediated inflammation directly impairs pulmonary function, contributing to the pathogenesis of Pneumocystis carinii pneumonia

1999 • 165 citations

Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice.

1992 • 155 citations

Predictors of Pneumocystis carinii pneumonia in HIV-infected persons. Pulmonary Complications of HIV Infection Study Group.

1997 • 150 citations

Significant Involvement of CCL2 (MCP-1) in Inflammatory Disorders of the Lung

2003 • 146 citations

3. Cytokines and chemokines

2006 • 143 citations

IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells.

1999 • 116 citations

CD4+ T cell–independent vaccination against Pneumocystis carinii in mice

2001 • 113 citations

IFN-γ and CD8+ T Cells Restore Host Defenses AgainstPneumocystis cariniiin Mice Depleted of CD4+ T Cells

1999 • 106 citations

Protection against Pneumocystis carinii pneumonia by antibodies generated from either T helper 1 or T helper 2 responses

1997 • 105 citations

Role of CD8+ lymphocytes in host defense against Pneumocystis carinii in mice

1996 • 100 citations

Role of gamma interferon in the host immune and inflammatory responses to Pneumocystis carinii infection

1997 • 79 citations

Immune reconstitution pneumonitis following Pneumocystis carinii pneumonia in HIV‐infected subjects

2002 • 79 citations

T Cytotoxic-1 CD8+ T Cells Are Effector Cells against Pneumocystis in Mice

2004 • 79 citations

Spontaneous Pneumocystis carinii pneumonia in immunodeficient mutant scid mice. Natural history and pathobiology.

1990 • 73 citations

Murine CD4⁺T Lymphocyte Subsets and Host Defense againstPneumocystis carinii

2000 • 71 citations

Increased Host Resistance againstPneumocystis cariniiPneumonia in γδ T-Cell-Deficient Mice: Protective Role of Gamma Interferon and CD8⁺T Cells

2002 • 64 citations

CD4⁺CD25⁺Regulatory T Cells Modulate the T-Cell and Antibody Responses inHelicobacter-Infected BALB/c Mice

2006 • 53 citations

CD8 T Cells Modulate CD4 T-Cell and Eosinophil-Mediated Pulmonary Pathology in Pneumocystis Pneumonia in B-Cell-Deficient Mice

2006 • 39 citations

The perforin mediated apoptotic pathway in lung injury and fibrosis

2004 • 37 citations