Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice.

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

1988 • 731 citations

CD4 Counts as Predictors of Opportunistic Pneumonias in Human Immunodeficiency Virus (HIV) Infection

1989 • 504 citations

RAISED SERUM LEVELS OF TUMOUR NECROSIS FACTOR IN PARASITIC INFECTIONS

1986 • 469 citations

Natural killer (NK) cells are present in mice with severe combined immunodeficiency (scid).

1985 • 362 citations

Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms.

1985 • 307 citations

Biologic activities and mechanisms of action of tumor necrosis factor-alpha/cachectin.

1991 • 256 citations

A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.

1990 • 250 citations

Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice.

1990 • 242 citations

Parasitologic and Serologic Observations of Infection with Pneumocystis in Humans

1977 • 240 citations

Serologic Responses to Pneumocystis carinii Antigens in Health and Disease

1990 • 236 citations

Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease.

1984 • 229 citations

Effect of T4 count and cofactors on the incidence of AIDS in homosexual men infected with human immunodeficiency virus

1987 • 220 citations

Passive immunoprophylaxis with specific monoclonal antibody confers partial protection against Pneumocystis carinii pneumonitis in animal models.

1988 • 170 citations

The interaction in vitro of Pneumocystis carinii with macrophages and L-cells.

1978 • 164 citations

Pneumocystis carinii and Toxoplasma gondii Infections in Patients with AIDS

1986 • 157 citations

The acute phase protein response during parasitic infection

1991 • 88 citations

Alveolar macrophages in AIDS patients: increased spontaneous tumour necrosis factor-alpha production inPneumocystis cariniipneumonia

1990 • 87 citations

Cachectic effects of recombinant human tumor necrosis factor in rats.

1990 • 83 citations

The function of antigen-presenting cells in mice with severe combined immunodeficiency.

1985 • 76 citations

Depletion of CD8+ cells in human thymic medulla results in selective immune deficiency.

1989 • 76 citations

Spontaneous Pneumocystis carinii pneumonia in immunodeficient mutant scid mice. Natural history and pathobiology.

1990 • 73 citations

Natural killer cells in the thymus. Studies in mice with severe combined immune deficiency.

1990 • 62 citations

Subpopulations of lymphoid and non-lymphoid cells in bronchus-associated lymphoid tissue (BALT) of the mouse.

1988 • 58 citations

Resistance to Mycoplasma pulmonis Mediated by Activated Natural Killer Cells

1990 • 48 citations

Cellular and humoral immune responses of mice subclinically infected with Pneumocystis carinii

1985 • 48 citations

IL-2 induces pulmonary edema and vasoconstriction independent of circulating lymphocytes.

1989 • 39 citations

Pneumocystis carinii Pneumonia in scid/scid Mice

1989 • 39 citations

Effect of T-cell transfer on Pneumocystis carinii infection in nude mice.

1984 • 36 citations

Pneumocystis carinii stimulates in vitro production of tumor necrosis factor-α by human macrophages

1991 • 35 citations

Pneumocystis carinii pneumonitis in patients with hypogammaglobulinemia and intact T cell immunity

1983 • 33 citations

Pneumocystis carinii pneumonia associated with profound lymphopenia and abnormal T-lymphocyte subset ratios during treatment for early-stage breast carcinoma

1991 • 32 citations

Experimental Pneumocystis carinii infection in nude rats.

1984 • 28 citations

T Cell-Independent Macrophage Activation in Scid Mice

1989 • 28 citations

Serum antibody responses to Pneumocystis carinii among different strains of normal and athymic mice

1982 • 25 citations

High-Dose Corticosteroid Therapy for Pneumocystis carinii Pneumonia in Patients With Acquired Immunodeficiency Syndrome

1989 • 20 citations

Identification of Pneumocystis carinii in immunodeficient mice.

1989 • 20 citations

The acute phase protein response during parasitic infection

1991 • 18 citations

Production of colony-stimulating factors during pneumonia caused by Chlamydia trachomatis

1991 • 18 citations

Acute Phase Response in Pneumocystis carinii Pneumonia

1990 • 15 citations

An Improved Method of Isolating Pneumocystis carinii from Infected Rat Lungs

1986 • 12 citations

The scid Mouse: A Model for Severe Combined Immune Deficiency1

2015 • 10 citations

Interaction of Pneumocystis carinii with Secretions of Alveolar Macrophages and Type II Epithelial Cells

1989 • 6 citations