A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Corticosteroid‐Mediated Immunoregulation in Man

1982 • 902 citations

Acquired Immunodeficiency Syndrome: Epidemiologic, Clinical, Immunologic, and Therapeutic Considerations

1984 • 871 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

1985 • 466 citations

Pneumocystis cariniiPneumonia in the United States

1974 • 408 citations

Trimethoprim-Sulfamethoxazole or Pentamidine forPneumocystis cariniiPneumonia in the Acquired Immunodeficiency Syndrome

1986 • 377 citations

T Cell Development in the Adult Murine Thymus: Changes in the Expression of the Surface Antigens Ly2, L3T4 and B2A2 during Development from Early Precursor Cells to Emigrants

1984 • 344 citations

Latent Pneumocystis infection of rats, relapse, and chemotherapy.

1966 • 343 citations

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

1988 • 265 citations

Monoclonal Antibodies Against Rat Immunoglobulin Kappa Chains

1982 • 257 citations

Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice.

1985 • 225 citations

Intensive Care of Patients with the Acquired Immunodeficiency Syndrome

1986 • 196 citations

Genetically Determined Murine Models of Immunodeficiency

1987 • 178 citations

Nude Mouse: A New Experimental Model for Pneumocystis carinii Infection

1977 • 151 citations

New rat model of Pneumocystis carinii infection

1988 • 136 citations

Correlation of cell surface antigen expression on human thymocytes by multi-color flow cytometric analysis: implications for differentiation.

1986 • 134 citations

Inhibition of humoral immunity in vivo by monoclonal antibody to L3T4: studies with soluble antigens in intact mice.

1985 • 116 citations

Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis

1984 • 114 citations

Species heterogeneity in macrophage expression of the CD4 antigen.

1987 • 103 citations

Cultivation of Pneumocystis carinii with WI-38 cells

1979 • 101 citations

Attachment of Pneumocystis carinii to rat pneumocytes.

1986 • 97 citations

Nonspecific Interstitial Pneumonitis without Evidence of Pneumocystis carinii in Asymptomatic Patients Infected with Human Immunodeficiency Virus (HIV)

1988 • 97 citations

Clearance of Giardia muris infection requires helper/inducer T lymphocytes.

1987 • 94 citations

Outbreaks of Pneumocystis carinii pneumonia in colonies of immunodeficient mice

1989 • 92 citations

Analysis of the developmental stages of Pneumocystis carinii, in vitro.

1988 • 87 citations

Engagement of the CD4 molecule influences cell surface expression of the T-cell receptor on thymocytes

1988 • 84 citations

Successful treatment with aerosolized pentamidine of Pneumocystis carinii pneumonia in rats

1987 • 78 citations

Uptake and degradation of Pneumocystis carinii by macrophages in vitro.

1978 • 72 citations

Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies.

1987 • 71 citations

Role of L3T4+ T cells in host defense against Histoplasma capsulatum

1988 • 69 citations

Administration of F(ab')2 fragments of monoclonal antibody to L3T4 inhibits humoral immunity in mice without depleting L3T4+ cells.

1986 • 67 citations

Comparison of histologic and quantitative techniques in evaluation of therapy for experimental Pneumocystis carinii pneumonia

1987 • 55 citations

Phospholipid profile of Pneumocystis carinii and its interaction with alveolar type II epithelial cells

1987 • 54 citations

Attachment of microbes to host cells: relevance of Pneumocystis carinii.

1986 • 45 citations

Pulmonary immune responses of inbred mice. Appearance of antibody-forming cells in C57BL/6 mice after intrapulmonary or systemic immunization with sheep erythrocytes.

1978 • 31 citations

Provocation of Infection Due to Pneumocystis carinii by Cyciosporin A

1982 • 29 citations

Treatment of murine lupus with monoclonal antibody to L3T4. I. Effects on the distribution and function of lymphocyte subsets and on the histopathology of autoimmune disease

1988 • 26 citations

Sources of rats free of latent Pneumocystis carinii

1987 • 23 citations

Effects of bacterial pneumonitis on development of pneumocystosis in rats.

1982 • 23 citations

Antibody to the Retrovirus Associated With the Acquired Immunodeficiency Syndrome (AIDS)

1986 • 22 citations

Immunological Studies of Pneumocystis carinii

1989 • 18 citations

In vitro differentiation of human-derived Pneumocystis carinii

1989 • 13 citations

Intensive Care of Patients with the Acquired Immunodeficiency Syndrome. Outcome and Changing Patterns of Utilization

1987 • 13 citations

CD 4-/CD 8- T cells: amplification in spleens of mice following in vivo treatment with monoclonal antibody anti-L3T4

1988 • 11 citations

Genetically Determined Murine Models Of Immunodeficiency

1987 • 11 citations

Antibody to the retrovirus associated with the acquired immunodeficiency syndrome (AIDS). Presence in presumably healthy San Franciscans who died unexpectedly

1986 • 6 citations

Decreased Yield of Pneumocystis carinii from Cortisonized Rats

1989 • 3 citations

Decreased yield of Pneumocystis carinii from cortisonized rats.

1989 • 3 citations

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