Immune-mediated inflammation directly impairs pulmonary function, contributing to the pathogenesis of Pneumocystis carinii pneumonia

Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies

1984 • 853 citations

Mechanics of Respiration in Unanesthetized Guinea Pigs

1958 • 644 citations

Pneumocystis cariniiPneumonia: Differences in Lung Parasite Number and Inflammation in Patients with and without AIDS

1989 • 456 citations

Consensus Statement on the Use of Corticosteroids as Adjunctive Therapy for Pneumocystis Pneumonia in the Acquired Immunodeficiency Syndrome

1990 • 374 citations

A new model of Pneumocystis carinii infection in mice selectively depleted of helper T lymphocytes.

1990 • 250 citations

Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice.

1990 • 242 citations

Lung Inflammation and Fibrosis

1998 • 220 citations

Pneumocystis carinii Pneumonia in Patients Without AIDS

1993 • 202 citations

Cytokines and particle-induced inflammatory cell recruitment.

1997 • 199 citations

Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice.

1992 • 155 citations

The role of cytokines and adhesion molecules in the development of inflammatory injury

1995 • 135 citations

Guidelines for Prophylaxis Against Pneumocystis carinii Pneumonia for Persons Infected With Human Immunodeficiency Virus

1989 • 123 citations

Inflammatory Responses to Pneumocystis carinii in Mice Selectively Depleted of Helper T Lymphocytes

1991 • 120 citations

IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cells.

1999 • 116 citations

Latency is not an inevitable outcome of infection with Pneumocystis carinii

1993 • 109 citations

IFN-γ and CD8+ T Cells Restore Host Defenses AgainstPneumocystis cariniiin Mice Depleted of CD4+ T Cells

1999 • 106 citations

Role of CD8+ lymphocytes in host defense against Pneumocystis carinii in mice

1996 • 100 citations

Prognostic value of interleukin-8 in AIDS-associated Pneumocystis carinii pneumonia.

1995 • 99 citations

Role of alveolar macrophages in lipopolysaccharide-induced neutrophil accumulation

1988 • 86 citations

Spontaneous Pneumocystis carinii pneumonia in immunodeficient mutant scid mice. Natural history and pathobiology.

1990 • 73 citations

Chemokine Gene Expression duringPneumocystis carinii-Driven Pulmonary Inflammation

1999 • 64 citations

Analysis of Cytokine mRNA Profiles in the Lungs ofPneumocystis carinii-infected Mice

1997 • 59 citations

Exogenous CD40 ligand induces a pulmonary inflammation response.

1997 • 58 citations

Development and resolution of Pneumocystis carinii pneumonia in severe combined immunodeficient mice: a morphological study of host inflammatory responses.

1992 • 49 citations

PATHOGENESIS AND HOST RESPONSE INPneumocystis cariniiPNEUMONIA

1994 • 45 citations

Pneumocystis carinii pneumonia in cancer patients

1993 • 31 citations

Lung Mechanics in Orally Immunized Mice after Aerolized Exposure to Influenza Virus

1984 • 20 citations

Immunology of idopathic pulmonary fibrosis

1996 • 14 citations

Lung mechanics, radiography and 67Ga scintigraphy in experimental Pneumocystis carinii pneumonia.

1986 • 13 citations

Course of pulmonary dysfunction in children surviving Pneumocystis carinii pneumonitis. A prospective study.

1981 • 10 citations

Course of Pulmonary Dysfunction in Children Surviving Pneumocystis carinii Pneumonitis

2015 • 10 citations