Tolerance induced by inhaled antigen involves CD4+ T cells expressing membrane-bound TGF-β and FOXP3
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References (57)
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 • 7,902 citations
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
2003 • 7,470 citations
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
2010 • 5,969 citations
A CD4+T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
1997 • 3,625 citations
An essential role for Scurfin in CD4+CD25+ T regulatory cells
2003 • 2,825 citations
The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells
1997 • 2,317 citations
CD4+CD25+ suppressor T cells: more questions than answers
2002 • 2,202 citations
Regulatory T Cell Clones Induced by Oral Tolerance: Suppression of Autoimmune Encephalomyelitis
1994 • 1,995 citations
Environmental Exposure to Endotoxin and Its Relation to Asthma in School-Age Children
2002 • 1,810 citations
The lineage decisions of helper T cells
2002 • 1,678 citations
Cell Contact–Dependent Immunosuppression by Cd4+Cd25+Regulatory T Cells Is Mediated by Cell Surface–Bound Transforming Growth Factor β
2001 • 1,609 citations
Natural versus adaptive regulatory T cells
2003 • 1,363 citations
Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation.
1996 • 1,335 citations
Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen
2001 • 1,212 citations
Distinct endocytic pathways regulate TGF-β receptor signalling and turnover
2003 • 1,115 citations
A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF
1988 • 1,105 citations
Pillars Article: Control of Regulatory T Cell Development by the Transcription Factor Foxp3. Science 2003. 299: 1057-1061.
2017 • 986 citations
Cell interactions in the induction of tolerance: the role of thymic lymphocytes.
1970 • 920 citations
The germless theory of allergic disease: revisiting the hygiene hypothesis
2001 • 794 citations
Antigen-specific regulatory T cells develop via the ICOS–ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
2002 • 785 citations
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the SId mutant
1991 • 740 citations
Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering.
1992 • 734 citations
TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses
2002 • 703 citations
Transcription Factor GATA-3 Is Differentially Expressed in Murine Th1 and Th2 Cells and Controls Th2-specific Expression of the Interleukin-5 Gene
1997 • 666 citations
Lineage commitment in the immune system: the T helper lymphocyte grows up
2000 • 627 citations
CD4+CD25+ Regulatory T Cells Can Mediate Suppressor Function in the Absence of Transforming Growth Factor β1 Production and Responsiveness
2002 • 614 citations
Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells
2002 • 528 citations
The TGF-α precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction
1989 • 482 citations
Lymphotoxin ?, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface
1993 • 468 citations
Oral tolerance in experimental autoimmune encephalomyelitis. III. Evidence for clonal anergy.
1991 • 450 citations
Antigen-driven bystander suppression after oral administration of antigens.
1991 • 438 citations
Transmembrane TGF-α precursors activate EGF/TGF-α receptors
1989 • 432 citations
A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact
1990 • 409 citations
Regulation of IgE Responses to Inhaled Antigen in Mice by Antigen-Specific γδ T Cells
1994 • 406 citations
Requirement for Tec Kinases Rlk and Itk in T Cell Receptor Signaling and Immunity
1999 • 399 citations
T Cell Receptor–initiated Calcium Release Is Uncoupled from Capacitative Calcium Entry in Itk-deficient T Cells
1998 • 336 citations
Inhibition of Allergic Inflammation in a Murine Model of Asthma by Expression of a Dominant-Negative Mutant of GATA-3
1999 • 333 citations
Impaired NFATc Translocation and Failure of Th2 Development in Itk-Deficient CD4+ T Cells
1999 • 307 citations
Essential Role of Nuclear Factor κB in the Induction of Eosinophilia in Allergic Airway Inflammation
1998 • 304 citations
Th2 cells and GATA-3 in asthma: new insights into the regulation of airway inflammation
1999 • 285 citations
Peripheral Autoantigen Induces Regulatory T Cells that Prevent Autoimmunity
1999 • 284 citations
Soluble and cell-bound forms of steel factor activity play distinct roles in melanocyte precursor dispersal and survival on the lateral neural crest migration pathway
1995 • 280 citations
Biochemical Interactions Integrating Itk with the T Cell Receptor-initiated Signaling Cascade
2000 • 278 citations
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 • 241 citations
B Cells Activated by Lipopolysaccharide, But Not By Anti-Ig and Anti-CD40 Antibody, Induce Anergy in CD8+ T Cells: Role of TGF-β1
2003 • 220 citations
Lymphotoxin
1988 • 205 citations
Internalization-Dependent and -Independent Requirements for Transforming Growth Factor β Receptor Signaling via the Smad Pathway
2002 • 187 citations
Transforming Growth Factor β Blocks Tec Kinase Phosphorylation, Ca2+ Influx, and NFATc Translocation Causing Inhibition of T Cell Differentiation
2003 • 163 citations
Aerosol-induced Immunoglobulin (Ig)-E Unresponsiveness to Ovalbumin Does Not Require CD8+ or T Cell Receptor (TCR)-γ/δ+ T Cells or Interferon (IFN)-γ in a Murine Model of Allergen Sensitization
1998 • 155 citations
The Absence of Interleukin 9 Does Not Affect the Development of Allergen-induced Pulmonary Inflammation nor Airway Hyperreactivity
2002 • 139 citations
Shifts in Lung Lymphocyte Profiles Correlate with the Sequential Development of Acute Allergic and Chronic Tolerant Stages in a Murine Asthma Model
1999 • 115 citations
A method for repeated evaluation of pulmonary performance in unanesthetized, unrestrained guinea pigs and its application to detect effects of sulfuric acid mist inhalation
1982 • 108 citations
Characterization of cis-Regulatory Elements and Nuclear Factors Conferring Th2-Specific Expression of the IL-5 Gene: A Role for a GATA-Binding Protein
1998 • 107 citations
Tec family kinases in lymphocyte signaling and function
2000 • 103 citations
Differential activities of secreted lymphotoxin-alpha3 and membrane lymphotoxin-alpha1beta2 in lymphotoxin-induced inflammation: critical role of TNF receptor 1 signaling.
1998 • 91 citations
Aerosol cyclosporine prevents acute allograft rejection in experimental lung transplantation
1998 • 36 citations
The Significance of Immune Suppression in Normal Self Tolerance
1996 • 32 citations
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