SIGNAL-MEDIATED SORTING OF MEMBRANE PROTEINS BETWEEN THE ENDOPLASMIC RETICULUM AND THE GOLGI APPARATUS

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

Mechanisms of intracellular protein transport

1994 • 2,280 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

COPII: A membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum

1994 • 1,294 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

Protein Oligomerization in the Endoplasmic Reticulum

1989 • 993 citations

BIOSYNTHETIC PROTEIN TRANSPORT AND SORTING BY THE ENDOPLASMIC RETICULUM AND GOLGI

1987 • 985 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

Interaction of Tyrosine-Based Sorting Signals with Clathrin-Associated Proteins

1995 • 955 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Signal-Dependent Membrane Protein Trafficking in the Endocytic Pathway

1993 • 808 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

1994 • 793 citations

Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

1992 • 741 citations

Quality control in the secretory pathway

1995 • 679 citations

Progress in Unraveling Pathways of Golgi Traffic

1985 • 615 citations

Coatomer Interaction with Di-Lysine Endoplasmic Reticulum Retention Motifs

1994 • 574 citations

Intracellular transport of class II MHC molecules directed by invariant chain

1990 • 548 citations

SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.

1991 • 544 citations

The retention signal for soluble proteins of the endoplasmic reticulum

1990 • 531 citations

'Coatomer': a cytosolic protein complex containing subunits of non-clathrin-coated Golgi transport vesicles

1991 • 524 citations

Pre- and post-golgi vacuoles operate in the transport of semliki forest virus membrane glycoproteins to the cell surface

1984 • 523 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Short cytoplasmic sequences serve as retention signals for transmembrane proteins in the endoplasmic reticulum

1989 • 499 citations

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

1992 • 497 citations

β-COP, a 110 kd protein associated with non-clathrin-coated vesicles and the golgi complex, shows homology to β-adaptin

1991 • 489 citations

VESICLE-MEDIATED PROTEIN SORTING

1992 • 472 citations

The Golgi Apparatus: Two Organelles in Tandem

1981 • 438 citations

Regulation of Protein Export From the Endoplasmic Reticulum

1988 • 421 citations

Retrieval of transmembrane proteins to the endoplasmic reticulum.

1993 • 414 citations

Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport.

1995 • 407 citations

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

1992 • 396 citations

Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum

1994 • 392 citations

Perturbation of cellular calcium induces secretion of luminal ER proteins

1989 • 370 citations

The T Cell Antigen Receptor: Insights into Organelle Biology

1990 • 361 citations

The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.

1995 • 341 citations

Characterization of the budding compartment of mouse hepatitis virus: evidence that transport from the RER to the Golgi complex requires only one vesicular transport step

1994 • 339 citations

A human homologue of the yeast HDEL receptor

1990 • 336 citations

β-COP is essential for biosynthetic membrane transport from the endoplasmic reticulum to the Golgi complex in vivo

1993 • 336 citations

Rab GTPases: master regulators of membrane trafficking

1994 • 315 citations

An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum.

1994 • 315 citations

Three-dimensional electron microscopy: structure of the Golgi apparatus.

1990 • 307 citations

Sar1 promotes vesicle budding from the endoplasmic reticulum but not Golgi compartments.

1994 • 304 citations

Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd protein

1992 • 291 citations

Kin recognition between medial Golgi enzymes in HeLa cells.

1994 • 278 citations

COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast

1995 • 278 citations

Rab proteins and the road maps for intracellular transport

1993 • 276 citations

Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast.

1994 • 265 citations

pH-dependent binding of KDEL to its receptor in vitro.

1993 • 232 citations

An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding.

1995 • 229 citations

A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments.

1994 • 226 citations

The endoplasmic reticulum—Golgi intermediate compartment

1992 • 224 citations

Kin recognition

1993 • 223 citations

A Peptide Sequence Confers Retention and Rapid Degradation in the Endoplasmic Reticulum

1990 • 219 citations

The Sec13p complex and reconstitution of vesicle budding from the ER with purified cytosolic proteins.

1993 • 219 citations

Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP.

1991 • 210 citations

Human 3-hydroxy-3-methylglutaryl coenzyme A reductase. Conserved domains responsible for catalytic activity and sterol-regulated degradation.

1985 • 199 citations

Localization of the Lys, Asp, Glu, Leu tetrapeptide receptor to the Golgi complex and the intermediate compartment in mammalian cells.

1994 • 197 citations

Molecular Cloning of a Human Genomic Region Containing the H Blood Group α(1,2)Fucosyltransferase Gene and Two H Locus-related DNA Restriction Fragments

1995 • 191 citations

Beta-COP localizes mainly to the cis-Golgi side in exocrine pancreas.

1993 • 190 citations

Site of addition of N-acetyl-galactosamine to the E1 glycoprotein of mouse hepatitis virus-A59.

1988 • 188 citations

Isolation of a matrix that binds medial Golgi enzymes

1994 • 181 citations

The Golgi-localization of yeast Emp47p depends on its di-lysine motif but is not affected by the ret1-1 mutation in alpha-COP.

1995 • 175 citations

Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins.

1995 • 170 citations

Oligomerization of a membrane protein correlates with its retention in the Golgi complex

1993 • 154 citations

Endoplasmic reticulum: a dynamic patchwork of specialized subregions.

1992 • 154 citations

Transport into and out of the Golgi complex studied by transfecting cells with cDNAs encoding horseradish peroxidase.

1994 • 147 citations

Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

1993 • 144 citations

GPI anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles.

1996 • 139 citations

Disruptions in Golgi structure and membrane traffic in a conditional lethal mammalian cell mutant are corrected by epsilon-COP.

1994 • 139 citations

Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro

1993 • 133 citations

The capacity to retrieve escaped ER proteins extends to the trans-most cisterna of the Golgi stack.

1995 • 129 citations

Palmitylation of Viral Membrane Glycoproteins Takes Place after Exit from the Endoplasmic Reticulum

1989 • 127 citations

Immunocytochemical localization of β-COP to the ER-Golgi boundary and the TGN

1995 • 127 citations

Signals for retention of transmembrane proteins in the endoplasmic reticulum studied with CD4 truncation mutants.

1991 • 122 citations

A soluble secretory protein is first concentrated in the endoplasmic reticulum before transfer to the Golgi apparatus.

1993 • 121 citations

ERGIC-53, a Membrane Protein of the Endoplasmic Reticulum-Golgi Intermediate Compartment, Is Identical to MR60, an Intracellular Mannose-specific Lectin of Myelomonocytic Cells

1995 • 121 citations

Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway.

1995 • 120 citations

Vma21p is a yeast membrane protein retained in the endoplasmic reticulum by a di-lysine motif and is required for the assembly of the vacuolar H(+)-ATPase complex.

1994 • 116 citations

COPs Regulating Membrane Traffic

1995 • 114 citations

About turn for the COPs?

1994 • 114 citations

In Vitro Assembly and Disassembly of Coatomer

1995 • 106 citations

Isolation and characterization of the methionine aminopeptidase from porcine liver responsible for the co-translational processing of proteins.

1992 • 99 citations

Steric masking of a dilysine endoplasmic reticulum retention motif during assembly of the human high affinity receptor for immunoglobulin E.

1995 • 97 citations

Intracellular protein trafficking defects in human disease

1992 • 96 citations

Sorting and traffic in the central vacuolar system

1989 • 95 citations

Nonclathrin coat protein gamma, a subunit of coatomer, binds to the cytoplasmic dilysine motif of membrane proteins of the early secretory pathway.

1996 • 94 citations

The KKXX signal mediates retrieval of membrane proteins from the Golgi to the ER in yeast.

1994 • 89 citations

The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.

1992 • 89 citations

Biosynthesis and processing of ribophorins in the endoplasmic reticulum.

1984 • 83 citations

Novel N-Terminal Amino Acid Sequence Required for Retention of a Hepatitis B Virus Glycoprotein in the Endoplasmic Reticulum

1989 • 82 citations

Xenopus oocytes can secrete bacterial β-lactamase

1984 • 79 citations

zeta-COP, a subunit of coatomer, is required for COP-coated vesicle assembly.

1993 • 75 citations

Carboxy-terminal SEKDEL sequences retard but do not retain two secretory proteins in the endoplasmic reticulum.

1989 • 68 citations

The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum

1995 • 67 citations

The Transmembrane Region of Microsomal Cytochrome P450 Identified as the Endoplasmic Reticulum Retention Signal1

1994 • 66 citations

A tyrosine-containing motif mediates ER retention of CD3-epsilon and adopts a helix-turn structure.

1995 • 66 citations

Transport of the vesicular stomatitis glycoprotein to trans Golgi membranes in a cell-free system.

1987 • 65 citations

Retention of membrane proteins by the endoplasmic reticulum.

1985 • 64 citations

Retention of p63 in an ER-Golgi intermediate compartment depends on the presence of all three of its domains and on its ability to form oligomers.

1994 • 63 citations

The signal peptide of the rotavirus glycoprotein VP7 is essential for its retention in the ER as an integral membrane protein

1989 • 63 citations

Immunochemical analysis of rough and smooth microsomes from rat liver. Segregation of docking protein in rough membranes

1985 • 57 citations

Targeting of proteins to the Golgi apparatus

1994 • 52 citations

Coatomer-rich endoplasmic reticulum.

1994 • 48 citations

gp74 a membrane glycoprotein of the cis-Golgi network that cycles through the endoplasmic reticulum and intermediate compartment

1994 • 44 citations

Different Fate of a Single Reporter Protein Containing KDEL or KKXX Targeting Signals Stably Expressed in Mammalian Cells

1996 • 37 citations

The surf-4 gene encodes a novel 30 kDa integral membrane protein

1995 • 36 citations

The endoplasmic reticulum retention signal of the E3/19K protein of adenovirus-2 is microtubule binding

1991 • 35 citations

Retention of a type II surface membrane protein in the endoplasmic reticulum by the Lys-Asp-Glu-Leu sequence.

1992 • 35 citations

Novel N-terminal amino acid sequence required for retention of a hepatitis B virus glycoprotein in the endoplasmic reticulum.

1989 • 32 citations

Restriction of docking protein to the rough endoplasmic reticulum: immunocytochemical localization in rat liver.

1985 • 31 citations

Retention by the endoplasmic reticulum of rotavirus VP7 is controlled by three adjacent amino-terminal residues

1994 • 29 citations

Drug metabolizing enzymes related to laboratory medicine: Cytochromes P-450 and UDP-glcuronosyltransferases

1994 • 27 citations

Cited By (0)

No citing papers found in database