Mutational analysis of the human KDEL receptor: distinct structural requirements for Golgi retention, ligand binding and retrograde transport.

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

1985 • 2,456 citations

A C-terminal signal prevents secretion of luminal ER proteins

1987 • 2,189 citations

Microtubule-dependent retrograde transport of proteins into the ER in the presence of brefeldin a suggests an ER recycling pathway

1990 • 972 citations

Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

1990 • 918 citations

Control of Protein Exit from the Endoplasmic Reticulum

1989 • 794 citations

Isolation of Monoclonal Antibodies Specific for Human c-myc Proto-Oncogene Product

1985 • 788 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway

1990 • 548 citations

The retention signal for soluble proteins of the endoplasmic reticulum

1990 • 531 citations

Evidence that luminal ER proteins are sorted from secreted proteins in a post-ER compartment.

1988 • 434 citations

Retrieval of transmembrane proteins to the endoplasmic reticulum.

1993 • 414 citations

Ligand-induced redistribution of a human KDEL receptor from the Golgi complex to the endoplasmic reticulum

1992 • 396 citations

A human homologue of the yeast HDEL receptor

1990 • 336 citations

Sequences within and adjacent to the transmembrane segment of alpha-2,6-sialyltransferase specify Golgi retention.

1991 • 296 citations

The ERD2 gene determines the specificity of the luminal ER protein retention system

1990 • 243 citations

The membrane spanning domain of beta-1,4-galactosyltransferase specifies trans Golgi localization.

1991 • 237 citations

pH-dependent binding of KDEL to its receptor in vitro.

1993 • 232 citations

Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum.

1991 • 215 citations

Differential effects of mutations in three domains on folding, quaternary structure, and intracellular transport of vesicular stomatitis virus G protein.

1988 • 210 citations

Recycling of proteins from the Golgi compartment to the ER in yeast.

1990 • 196 citations

A Golgi retention signal in a membrane-spanning domain of coronavirus E1 protein.

1991 • 185 citations

Molecular cloning, characterization, subcellular localization and dynamics of p23, the mammalian KDEL receptor.

1993 • 154 citations

The signal for Golgi retention of bovine beta 1,4-galactosyltransferase is in the transmembrane domain.

1992 • 148 citations

A brefeldin A-like phenotype is induced by the overexpression of a human ERD-2-like protein, ELP-1

1992 • 148 citations

The 17-residue transmembrane domain of beta-galactoside alpha 2,6-sialyltransferase is sufficient for Golgi retention

1992 • 126 citations

Genes that allow yeast cells to grow in the absence of the HDEL receptor.

1992 • 112 citations

The Saccharomyces cerevisiae SEC20 gene encodes a membrane glycoprotein which is sorted by the HDEL retrieval system.

1992 • 89 citations

Different sorting of Lys-Asp-Glu-Leu proteins in rat liver.

1992 • 89 citations

Sequence of a second human KDEL receptor

1992 • 85 citations

Bos1p, a membrane protein required for ER to Golgi transport in yeast, co-purifies with the carrier vesicles and with Bet1p and the ER membrane.

1992 • 79 citations

Changing the specificity of the sorting receptor for luminal endoplasmic reticulum proteins

1992 • 28 citations